G. Christian Overton

SORTEZ: A Relational Translator for NCBI's ASN.1 Database (2007)

Kyle W. Hart, David B. Searls, G. Christian Overton, Keywords Asn, Schema Translation, Relational Databases

The National Center for Biotechnology Information (NCBI) has created a database collection that includes several protein and nucleic acid sequence databases, a biosequencespecific subset of MEDLINE,...

In Memoriam- (2005)

Jonathan Schug, C. Pierce, Jonathan Schug, G. Christian Overton

Though his name does not appear on the title page as my advisor, without Chris Overton, who sadly passed away June 1, 2000, this dissertation would not be what it is. My interest in transcription...

Generation of patterns from gene expression data by assigning confidence to differentially expressed genes (2000)

Manduchi, Elisabetta, Grant, Gregory R., McKenzie, Steven E., Overton, G. Christian, Surrey, Saul, Stoeckert, Christian J.

Motivation: A protocol is described to attach expression patterns to genes represented in a collection of hybridization array experiments. Discrete values are used to provide an easily interpretable...

EpoDB: a database of genes expressed during vertebrate erythropoiesis (1998)

Fidel Salas, Juergen Haas, Brian Brunk, Christian J. Stoeckert, G. Christian Overton

EpoDB is a database designed for the study of gene regulation during differentiation and development of vertebrate red blood cells. In building EpoDB, we have taken the in advance approach to the...

EpoDB: a database of genes expressed during vertebrate erythropoiesis (1998)

Fidel Salas, Juergen Haas, Brian Brunk, Christian J. Stoeckert, G. Christian Overton

EpoDB is a database designed for the study of gene regulation during differentiation and development of vertebrate red blood cells. In building EpoDB, we have taken the in advance approach to the...

The GAIA software framework for genome annotation (1998)

G. Christian Overton, Charles Bailey, Jonathan Crabtree, Mark Gibson, Stephen Fischer, Jonathan Schug

We describe a software framework, GAIA, that supports semiautomated annotation of uncharacterized sequence data. The annotation framework incorporates annotation by data source integration, data...

Tess: Transcription element search software on the www (1997)

Jonathan Schug, G. Christian Overton

TESS, Transcription Element Search Software, is a web-based software tool for locating possible transcription factor binding sites in DNA sequence and for browsing the TRANSFAC database. It provides...

Integration of physical, breakpoint and genetic maps of chromosome 22. Localization of 587 yeast artificial chromosomes with 238 mapped markers (1995)

J.Bell, Callum, L.Budarf, Marcia, W.Nieuwenhuijsen, Bart, L.Barnoski, Barry, H.Buetow, Kenneth, Campbell, Keely, ...

Detailed physical maps of the human genome are important resources for the Identification and isolation of disease genes and for studying the structure and function of the genome. We used data from...

Application of Hidden Markov Modeling to the Characterization of Transcription Factor Binding Sites (1994)

Rajasekhar Raman, G. Christian Overton

The regulation of gene transcription in eukaryotes, though not well understood, is known to involve sequence specific recognition and binding of short DNA sequences (transcription elements) by...

QGB: A System for Querying Sequence Database Fields and Features (1994)

G. Christian Overton, Jeffrey S. Aaronson, Juergen Haas, Julie Adams

We have developed a general system, QGB, for performing complex queries on the information in the DDBJ/EMBL/GenBank databases, including queries over the structural features of sequences implied in...

SORTEZ: a relational translator for NCBI's ASN.1 database (1994)

Hart, Kyle W., Searls, David B., Overton, G.Christian

The National Center for Biotechnology Information (NCBI) has created a database collection that includes several protein and nucleic acid sequence databases, abiosequence-specific subset of MEDLINE,...

Knowledge Discovery in GenBank (1993)

Jeffrey S. Aaronson, Juergen Haas, G. Christian Overton

We describe various methods designed to discover knowledge in the GenBank nucleic acid sequence database. Using a grammatical model of gene structure, we create a parse tree of a gene using features...

Analogical Reasoning for Knowledge Discovery in a Molecular Biology Database (1993)

Juergen Haas, Jeffrey S. Aaronson, G. Christian Overton

Genes are highly structured objects. Identifying genetic structure is experimentally costly and in general, is only partially determined in the lab. As such, genomic databases such as GenBank are...