G. Cole

The Application of Life Cycle Assessment Technique in the Investigation of Brick Arch Highway Bridges by (2009)

G. Cole, Dr. G. Parke, B. Clarke, Prof J. Harding

Surrey County Council is the principal owner of highway infrastructure within its boundaries and is directly responsible for over 2,000 bridges across the County highway network. Historically the...

Remote diagnosis of leakage in residential households (2008)

Britton, Tracy Clare, Cole, G, Stewart, Rodney Anthony, Wiskar, D

Wide Bay Water Corporation is in the process of implementing automated meter reading technology in their water network. This technology allows the remote measurement and evaluation of water...

Remote diagnosis of leakage in residential households (2008)

Britton, Tracy Clare, Cole, G, Stewart, Rodney Anthony, Wiskar, D

Wide Bay Water Corporation is in the process of implementing automated meter reading technology in their water network. This technology allows the remote measurement and evaluation of water...

Remote diagnosis of leakage in residential households (2008)

Britton, Tracy Clare, Cole, G, Stewart, Rodney Anthony, Wiskar, D

Wide Bay Water Corporation is in the process of implementing automated meter reading technology in their water network. This technology allows the remote measurement and evaluation of water...

Sustainable water use in Europe Part 1: Sectoral use of water Prepared by: (2007)

W. Krinner, C. Lallana, T. Estrela, S. Nixon, T. Zabel, L. Laffon, ...

The contents of this report do not necessarily reflect the official opinion of the European Communities or other European Communities institutions. Neither the European Environment Agency nor any...

Evolution of the mating type locus: Insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii (2007)

Fraser, J., Stajich, J., Tarcha, E., Cole, G., Inglis, D., Sil, A., ...

Sexual reproduction of fungi is governed by the mating type (MAT) locus, a specialized region of the genome encoding key transcriptional regulators that direct regulatory networks to specify cell...

Evolution of the mating type locus: Insights gained from the dimorphic primary fungal pathogens Histoplasma capsulatum, Coccidioides immitis, and Coccidioides posadasii (2007)

Fraser, J., Stajich, J., Tarcha, E., Cole, G., Inglis, D., Sil, A., ...

Sexual reproduction of fungi is governed by the mating type (MAT) locus, a specialized region of the genome encoding key transcriptional regulators that direct regulatory networks to specify cell...

STUDY OF PILOT-CONTROLLER INTEGRATION FOR EMERGENCY CONDITIONS, (2005)

Cole,G., Bender,M., Shoquist,R., Santella,R., Lovinger,D.

The objective of this program was to develop a design concept which will minimize catastropic flight control failures through appropriate pilotcontroller integration. This report describes a...

Attentional capture by colour and motion in cerebral achromatopsia. (2003)

Cole, G., Heywood, C A. A., Kentridge, R. W., Fairholm, I., Cowey, A.

Cerebral achromatopsia is a rare condition in which damage to the ventromedial occipital area of the cortex results in the loss of previous termcolournext term experience. Nevertheless, cortically...

CEREBELLAR HAEMANGIOBLASTOMA AND VON HIPPEL-LINDAU DISEASE (1986)

HUSON, S. M., HARPER, P. S., HOURIHAN, M. D., COLE, G., WEEKS, R. D., COMPSTON, D. A. S.

Von Hippel-Lindau disease is an autosomal dominant multisystem disorder, the commonest presenting manifestations of which are haemangioblastomas of the cerebellum and retina. Affected individuals are...

NEUROLOGICAL TOXICITY OF THE SUBARACHNOID INFUSION OF BUPIVACAINE, LIGNOCAINE OR 2-CHLOROPROCAINE IN THE RAT (1985)

LI, DOMINIC F., BAHAR, M., COLE, G., ROSEN, M.

Neurotoxicity after subarachnoid infusion of bupivacaine, lignocaine and 2-chloroprocaine was studied in a chronic rat model. Hartmann's solution 100 μl h−1 was infused as a control, and...

In vitro activity of A-86719.1, a novel 2-pyridone antimicrobial agent.

Eliopoulos, G M, Wennersten, C B, Cole, G, Chu, D, Pizzuti, D, Moellering, R C

This study evaluated the in vitro activity of A-86719.1, a novel 2-pyridone antimicrobial agent. The drug inhibited all tested members of the family Enterobacteriaceae at < or = 0.5 microgram/ml and...

Detection of Mycobacterium tuberculosis in respiratory specimens by strand displacement amplification of DNA.

Down, J A, O'Connell, M A, Dey, M S, Walters, A H, Howard, D R, Little, M C, ...

A total of 294 clinical respiratory specimens, including 75 with culture-positive results, were tested for the presence of Mycobacterium tuberculosis by strand displacement amplification (SDA) of...

In vitro activities of two glycylcyclines against gram-positive bacteria.

Eliopoulos, G M, Wennersten, C B, Cole, G, Moellering, R C

The glycylcyclines designated CL 329,998 and CL 331,002 are N,N-dimethylglycylamido derivatives of minocycline and 6-demethyl-6-deoxytetracycline, respectively. In vitro activities of these two...

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.

Schubert, D, LaCorbiere, M, Saitoh, T, Cole, G

A secreted form of the amyloid beta protein precursor was isolated from the growth conditioned medium of the PC12 sympathetic nerve-like cell line. This protein is recognized by an antiserum that...

Molecular cloning and characterization of the glucoamylase gene of Aspergillus awamori.

Nunberg, J H, Meade, J H, Cole, G, Lawyer, F C, McCabe, P, Schweickart, V, ...

The filamentous ascomycete Aspergillus awamori secretes large amounts of glucoamylase upon growth in medium containing starch, glucose, or a variety of hexose sugars and sugar polymers. We examined...

Histogenesis of haemangioblastomas: an immunocytochemical and ultrastructural study in a case of von Hippel-Lindau syndrome.

Ismail, S M, Jasani, B, Cole, G

The cerebellar, retinal, and one of the spinal haemangioblastomas in a case of von Hippel-Lindau syndrome were studied by immunocytochemistry and electron microscopy. The tumours were positive for...

Differential methylation of the c-H-ras gene in normal mouse cells and during skin tumour progression.

Ramsden, M, Cole, G, Smith, J, Balmain, A

We have previously shown that the mouse c-H-ras gene acquires transforming activity in chemically induced skin tumours. We have now investigated the pattern of DNA methylation at HpaII and XhoI sites...

In vitro activity of A-86719.1, a novel 2-pyridone antimicrobial agent.

Eliopoulos, G M, Wennersten, C B, Cole, G, Chu, D, Pizzuti, D, Moellering, R C

This study evaluated the in vitro activity of A-86719.1, a novel 2-pyridone antimicrobial agent. The drug inhibited all tested members of the family Enterobacteriaceae at < or = 0.5 microgram/ml and...

Detection of Mycobacterium tuberculosis in respiratory specimens by strand displacement amplification of DNA.

Down, J A, O'Connell, M A, Dey, M S, Walters, A H, Howard, D R, Little, M C, ...

A total of 294 clinical respiratory specimens, including 75 with culture-positive results, were tested for the presence of Mycobacterium tuberculosis by strand displacement amplification (SDA) of...

In vitro activities of two glycylcyclines against gram-positive bacteria.

Eliopoulos, G M, Wennersten, C B, Cole, G, Moellering, R C

The glycylcyclines designated CL 329,998 and CL 331,002 are N,N-dimethylglycylamido derivatives of minocycline and 6-demethyl-6-deoxytetracycline, respectively. In vitro activities of these two...

Characterization of an amyloid beta precursor protein that binds heparin and contains tyrosine sulfate.

Schubert, D, LaCorbiere, M, Saitoh, T, Cole, G

A secreted form of the amyloid beta protein precursor was isolated from the growth conditioned medium of the PC12 sympathetic nerve-like cell line. This protein is recognized by an antiserum that...

Molecular cloning and characterization of the glucoamylase gene of Aspergillus awamori.

Nunberg, J H, Meade, J H, Cole, G, Lawyer, F C, McCabe, P, Schweickart, V, ...

The filamentous ascomycete Aspergillus awamori secretes large amounts of glucoamylase upon growth in medium containing starch, glucose, or a variety of hexose sugars and sugar polymers. We examined...

Histogenesis of haemangioblastomas: an immunocytochemical and ultrastructural study in a case of von Hippel-Lindau syndrome.

Ismail, S M, Jasani, B, Cole, G

The cerebellar, retinal, and one of the spinal haemangioblastomas in a case of von Hippel-Lindau syndrome were studied by immunocytochemistry and electron microscopy. The tumours were positive for...

Differential methylation of the c-H-ras gene in normal mouse cells and during skin tumour progression.

Ramsden, M, Cole, G, Smith, J, Balmain, A

We have previously shown that the mouse c-H-ras gene acquires transforming activity in chemically induced skin tumours. We have now investigated the pattern of DNA methylation at HpaII and XhoI sites...

Design of a software tool for PV-system-specific lightning protection

Linhart, F., Calais, M., Cole, G., Hinrichsen, V.

Photovoltaic (PV) systems are often installed on rooftops or as freestanding systems with no higher surrounding structures. This is why they are often exposed to the influences of lightning which can...

Disc oedema in association with Hunter's syndrome: ocular histopathological findings.

Beck, M, Cole, G

The histopathology of the posterior half of one eye and the optic nerves of a man with Hunter's syndrome, who was known to have disc oedema without raised intracranial pressure for 11 years of his...

HCV and HIV binding lectin, DC-SIGNR, is expressed at all stages of HCV induced liver disease

Cole, G, Coleman, N, Soilleux, E

The process by which hepatitis C virus (HCV) enters cells and the reason for its hepatotropism remain obscure. Recently, the human immunodeficiency virus (HIV) binding lectins, DC-SIGN and DC-SIGNR,...

Crural hypertrophy associated with centronuclear myopathy

Bill, P., Cole, G., Proctor, N. S. F., Saffer, D., Botes, A.

A case of centronuclear myopathy of adult onset with striking hypertrophy of lower limb muscles in a black South African man is described with details of the light microscopic, histochemical, and...

Centronuclear myopathy.

Bill, P L, Cole, G, Proctor, N S

Centronuclear myopathy occurring sporadically in two African female children is reported, with details of clinical history and histological, histochemical, and ultrastructural findings, and a review...

Alexander's disease: case report including histopathological and electron microscopic features.

Cole, G, De Villiers, F, Proctor, N S, Freiman, I, Bill, P

We report a case of Alexander's disease in a black South African boy of 9 years. The child presented with a grossly abnormal stooped posture, generalised weakness, and slurred nasal speech....

X linked neonatal centronuclear/myotubular myopathy: evidence for linkage to Xq28 DNA marker loci.

Thomas, N S, Williams, H, Cole, G, Roberts, K, Clarke, A, Liechti-Gallati, S, ...

We have studied the inheritance of several polymorphic Xq27/28 DNA marker loci in two three generation families with the X linked neonatal lethal form of centronuclear/myotubular myopathy (XL MTM)....

Acute cerebral demyelination: clinical and pathological correlation with computed tomography.

Loizou, L A, Cole, G

A 30-year-old woman died eleven weeks after the onset of an acute illness during which she developed quadriplegia, dysphasia, incontinence, confusion, emotional lability and gaze palsies. The CT scan...

Intracranial space-occupying masses in mental hospital patients: necropsy study.

Cole, G

During a three year period 1970--1973 necropsies were performed on 200 patients who died in a mental hospital in the Transvaal, South Africa. There was no selection of cases other than availability...

Fragile X syndrome with FMR1 and FMR2 deletion

Moore, S, Strain, L, Cole, G, Miedzybrodzka, Z, Kelly, K, Dean, J

We report a 13 year old boy with fragile X syndrome resulting from a de novo deletion of the FMR1 and FMR2 genes extending from (and including) DXS7536 proximally to FMR2 distally. The patient has...

The effects of prenatal care utilization and maternal risk factors on pregnancy outcome between Mexican Americans and non-Hispanic whites.

Balcazar, H., Hartner, J., Cole, G.

This study evaluates the effects of prenatal care classification and levels of maternal risk status on pregnancy outcomes in Mexican Americans and non-Hispanic whites in Arizona. All live birth...