G. D. Perkin

Neurological manifestations of the hyperventilation syndrome.

Perkin, G D, Joseph, R

Seventy-eight patients with the hyperventilation syndrome are described, none of whom had been diagnosed prior to referral for neurological assessment. There is a constellation of symptoms associated...

Pattern of neurological outpatient practice: implications for undergraduate and postgraduate training.

Perkin, G D

A case analysis has been performed on 4000 successive outpatient referrals to one consultant neurologist, representing 72% of all referrals to Charing Cross Hospital and 82% to Hillingdon Hospital. A...

Posture and lumbar puncture headache: a controlled trial in 50 patients.

Handler, C E, Smith, F R, Perkin, G D, Rose, F C

A prospective single blind trial in 50 patients was performed to investigate the effect of posture on post lumbar puncture headache (LPH). A difference between the frequency of headache at five hours...

Necessity for inpatient services in neurological practice.

Perkin, G D

An analysis has been performed of the case material referred to a single neurologist in one year, including outpatient referrals, ward referrals and those patients admitted directly from other...

Neurological manifestations of the hyperventilation syndrome.

Perkin, G D, Joseph, R

Seventy-eight patients with the hyperventilation syndrome are described, none of whom had been diagnosed prior to referral for neurological assessment. There is a constellation of symptoms associated...

Pattern of neurological outpatient practice: implications for undergraduate and postgraduate training.

Perkin, G D

A case analysis has been performed on 4000 successive outpatient referrals to one consultant neurologist, representing 72% of all referrals to Charing Cross Hospital and 82% to Hillingdon Hospital. A...

Posture and lumbar puncture headache: a controlled trial in 50 patients.

Handler, C E, Smith, F R, Perkin, G D, Rose, F C

A prospective single blind trial in 50 patients was performed to investigate the effect of posture on post lumbar puncture headache (LPH). A difference between the frequency of headache at five hours...

Necessity for inpatient services in neurological practice.

Perkin, G D

An analysis has been performed of the case material referred to a single neurologist in one year, including outpatient referrals, ward referrals and those patients admitted directly from other...

Uhthoff's syndrome.

Perkin, G. D., Rose, F. C.

A total of 125 patients with a previous episode of optic neuritis was followed to assess the subsequent prevalence of transient visual blurring. 32.8 per cent developed this symptom and the...

A trial of brolitene in the treatment of spasticity.

Perkin, G D, Aminoff, M J

A new anti-spasticity agent, brolitene, has been assessed in patients with spasticity of spinal or cerebral origin. Twenty-seven patients were entered in a double-blind cross-over trial lasting 6...

Enhanced binding of lymphocytes from patients with multiple sclerosis to tumour necrosis factor-alpha (TNF-α)-treated endothelial monolayers: associations with clinical relapse and adhesion molecule expression

VORA, A J, PERKIN, G D, McCOY, T, DUMONDE, D C, BROWN, K A

This study investigated the adherent properties and adhesion molecule expression of blood mononuclear cells (MNC) from a total of 84 patients with multiple sclerosis (MS). The MNC from MS patients...

A trial of corticotrophin gelatin injection in acute optic neuritis

Bowden, A. N., Bowden, P. M. A., Friedmann, A. I., Perkin, G. D., Rose, F. C.

The effect of a 30 day course of corticotrophin gelatin injections on the natural history of acute unilateral optic neuritis in 27 patients is reported. A further 27 patients received inert...

A relationship between claudication of the cauda equina and the small aorta syndrome.

Poskitt, K R, Perkin, G D, Greenhalgh, R M

Two cases of claudication of the cauda equina due to ischaemia secondary to distal aortic disease in the Small Aorta syndrome are reported. The association has not been previously reported and the...

T lymphocyte-derived demyelinating activity in multiple sclerosis patients in relapse.

Selmaj, K, Alam, R, Perkin, G D, Rose, F C

Supernatants of cultured T lymphocytes of multiple sclerosis patients were tested for a demyelinating activity in rat cerebellum explant cultures. Supernatants of unstimulated T lymphocytes in seven...

The association of hemifacial spasm and facial pain.

Perkin, G D, Illingworth, R D

The recognition of an association between trigeminal neuralgia and ipsilateral hemifacial spasm has been delayed by confusion over the nomenclature of the two conditions. Three patients are presented...

An analysis of 7836 successive new outpatient referrals.

Perkin, G D

An analysis has been performed of 7836 successive new outpatient referrals seen by one consultant neurologist. In approximately a quarter of the patients, a specific diagnosis was not possible. A...

Ischaemic lateral popliteal nerve palsy due to ergot intoxication

Perkin, G. D.

A patient with ergot intoxication due to medication for migraine developed lateral popliteal nerve palsy. This is attributed to recurrent ischaemia caused by ergotamine.