Ludmerer, S W, Benincasa, D, Mark, G E
Characterization of virus binding by neutralizing antibodies is important both in understanding early events in viral infectivity and in development of vaccines. Neutralizing monoclonal antibodies...
Conley, A J, Kessler JA, I I, Boots, L J, McKenna, P M, Schleif, W A, Emini, E A, ...
The anti-gp41 virus neutralizing monoclonal antibody 2F5 was infused into chimpanzees, which were then given an intravenous challenge with a primary human immunodeficiency virus type I (HIV-1)...
Ludmerer, S W, Benincasa, D, Mark, G E, Christensen, N D
A panel of monoclonal antibodies (MAbs) which neutralize human papillomavirus type 11 (HPV11) in the athymic mouse xenograph neutralization assay and bind HPV11 virus-like particles (VLPs) has been...
The mink cell focus-forming (MCF) class of recombinant murine leukemia viruses (CI-1 to 4) were isolated from iododeoxyuridine-induced C3H/MCA 5 cells in culture and molecularly cloned. These genomes...
Molecular cloning of a family of retroviral sequences found in chimpanzee but not human DNA.
Bonner, T I, Birkenmeier, E H, Gonda, M A, Mark, G E, Searfoss, G H, Todaro, G J
A number of retrovirus-like sequences have been cloned from chimpanzee DNA which constitute the chimpanzee homologs of the endogenous colobus type C virus CPC-1. One of the clones contains a nearly...
Bassuk, J A, Kao, W W, Herzer, P, Kedersha, N L, Seyer, J, DeMartino, J A, ...
Prolyl 4-hydroxylase (EC 1.14.11.2) is a key enzyme required for the posttranslational hydroxylation of proline residues in collagen. The enzyme is a tetramer composed of two pairs of nonidentical...
Pfeifer, A M, Mark, G E, Malan-Shibley, L, Graziano, S, Amstad, P, Harris, C C
Overexpression of c-raf-1 and the myc family of protooncogenes is primarily associated with small cell carcinoma, which accounts for approximately 25% of human lung cancer. To determine the...
Daugherty, B L, DeMartino, J A, Law, M F, Kawka, D W, Singer, I I, Mark, G E
Two novel approaches of recombinant PCR technology were employed to graft the complementarity determining regions from a murine monoclonal antibody (mAb) onto human antibody frameworks. One approach...
Kan, N C, Flordellis, C S, Mark, G E, Duesberg, P H, Papas, T S
The 5.2-kilobase (kb) RNA genome of avian carcinoma virus MH2 has the genetic structure 5'-delta gag (0.2 kb)- mht (1.2 kb)-myc (1.4 kb)-c (0.4 kb)-poly(A) (0.2 kb)-3'. delta gag is a partial...
Avian sarcoma virus-transformed quail clones defective in the production of focus-forming virus.
Mason, W S, Hsu, T W, Yeater, C, Sabran, J L, Mark, G E, Kaji, A, ...
Quail embryo fibroblasts were infected at low multiplicity with avian sarcoma virus, and transformed cells were selected by their ability to form colonies in agar. Five clones that failed to produce...
Drosophila melanogaster homologs of the raf oncogene.
Mark, G E, MacIntyre, R J, Digan, M E, Ambrosio, L, Perrimon, N
A murine v-raf probe, representing the kinase domain, was used to identify two unique loci in Drosophila melanogaster DNA. The most closely related to v-raf was mapped by in situ hybridization to...
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus.
Rapp, U R, Goldsborough, M D, Mark, G E, Bonner, T I, Groffen, J, Reynolds, F H, ...
We have molecularly cloned a unique acutely transforming replication-defective mouse type C virus (3611-MSV) and characterized its acquired oncogene. The viral genome closely resembles Moloney (M)...
Pks, a raf-related sequence in humans.
Mark, G E, Seeley, T W, Shows, T B, Mountz, J D
A human fetal liver cDNA library was screened at reduced hybridization stringency for v-raf-related sequences. In addition to the expected c-raf-1 cDNA, a second sequence was isolated. Comparison of...
Analysis of unintegrated avian RNA tumor virus double-stranded DNA intermediates.
Hsu, T W, Sabran, J L, Mark, G E, Guntaka, R V, Taylor, J M
Previous studies by Guntaka et al. have shown that the unintegrated DNA intermediates of avian RNA tumor virus replication can be readily isolated from cultures of the quail tumor line QT-6 at 1 day...
Pfeifer, A M, Lechner, J F, Masui, T, Reddel, R R, Mark, G E, Harris, C C
The majority of human lung cancers arise from bronchial epithelial cells. The normal pseudostratified bronchial epithelium is composed of basal, mucous, and ciliated cells. This multi-differentiated...
Ludmerer, S W, Benincasa, D, Mark, G E
Characterization of virus binding by neutralizing antibodies is important both in understanding early events in viral infectivity and in development of vaccines. Neutralizing monoclonal antibodies...
Conley, A J, Kessler JA, I I, Boots, L J, McKenna, P M, Schleif, W A, Emini, E A, ...
The anti-gp41 virus neutralizing monoclonal antibody 2F5 was infused into chimpanzees, which were then given an intravenous challenge with a primary human immunodeficiency virus type I (HIV-1)...
Ludmerer, S W, Benincasa, D, Mark, G E, Christensen, N D
A panel of monoclonal antibodies (MAbs) which neutralize human papillomavirus type 11 (HPV11) in the athymic mouse xenograph neutralization assay and bind HPV11 virus-like particles (VLPs) has been...
The mink cell focus-forming (MCF) class of recombinant murine leukemia viruses (CI-1 to 4) were isolated from iododeoxyuridine-induced C3H/MCA 5 cells in culture and molecularly cloned. These genomes...
Molecular cloning of a family of retroviral sequences found in chimpanzee but not human DNA.
Bonner, T I, Birkenmeier, E H, Gonda, M A, Mark, G E, Searfoss, G H, Todaro, G J
A number of retrovirus-like sequences have been cloned from chimpanzee DNA which constitute the chimpanzee homologs of the endogenous colobus type C virus CPC-1. One of the clones contains a nearly...
Bassuk, J A, Kao, W W, Herzer, P, Kedersha, N L, Seyer, J, DeMartino, J A, ...
Prolyl 4-hydroxylase (EC 1.14.11.2) is a key enzyme required for the posttranslational hydroxylation of proline residues in collagen. The enzyme is a tetramer composed of two pairs of nonidentical...
Pfeifer, A M, Mark, G E, Malan-Shibley, L, Graziano, S, Amstad, P, Harris, C C
Overexpression of c-raf-1 and the myc family of protooncogenes is primarily associated with small cell carcinoma, which accounts for approximately 25% of human lung cancer. To determine the...
Daugherty, B L, DeMartino, J A, Law, M F, Kawka, D W, Singer, I I, Mark, G E
Two novel approaches of recombinant PCR technology were employed to graft the complementarity determining regions from a murine monoclonal antibody (mAb) onto human antibody frameworks. One approach...
Kan, N C, Flordellis, C S, Mark, G E, Duesberg, P H, Papas, T S
The 5.2-kilobase (kb) RNA genome of avian carcinoma virus MH2 has the genetic structure 5'-delta gag (0.2 kb)- mht (1.2 kb)-myc (1.4 kb)-c (0.4 kb)-poly(A) (0.2 kb)-3'. delta gag is a partial...
Avian sarcoma virus-transformed quail clones defective in the production of focus-forming virus.
Mason, W S, Hsu, T W, Yeater, C, Sabran, J L, Mark, G E, Kaji, A, ...
Quail embryo fibroblasts were infected at low multiplicity with avian sarcoma virus, and transformed cells were selected by their ability to form colonies in agar. Five clones that failed to produce...
Drosophila melanogaster homologs of the raf oncogene.
Mark, G E, MacIntyre, R J, Digan, M E, Ambrosio, L, Perrimon, N
A murine v-raf probe, representing the kinase domain, was used to identify two unique loci in Drosophila melanogaster DNA. The most closely related to v-raf was mapped by in situ hybridization to...
Structure and biological activity of v-raf, a unique oncogene transduced by a retrovirus.
Rapp, U R, Goldsborough, M D, Mark, G E, Bonner, T I, Groffen, J, Reynolds, F H, ...
We have molecularly cloned a unique acutely transforming replication-defective mouse type C virus (3611-MSV) and characterized its acquired oncogene. The viral genome closely resembles Moloney (M)...
Pks, a raf-related sequence in humans.
Mark, G E, Seeley, T W, Shows, T B, Mountz, J D
A human fetal liver cDNA library was screened at reduced hybridization stringency for v-raf-related sequences. In addition to the expected c-raf-1 cDNA, a second sequence was isolated. Comparison of...
Analysis of unintegrated avian RNA tumor virus double-stranded DNA intermediates.
Hsu, T W, Sabran, J L, Mark, G E, Guntaka, R V, Taylor, J M
Previous studies by Guntaka et al. have shown that the unintegrated DNA intermediates of avian RNA tumor virus replication can be readily isolated from cultures of the quail tumor line QT-6 at 1 day...
Pfeifer, A M, Lechner, J F, Masui, T, Reddel, R R, Mark, G E, Harris, C C
The majority of human lung cancers arise from bronchial epithelial cells. The normal pseudostratified bronchial epithelium is composed of basal, mucous, and ciliated cells. This multi-differentiated...