An update on the mouse liver proteome (2009)
Background: Decoding of the liver proteome is subject of intense research, but hampered by methodological constraints. We recently developed an improved protocol for studying rat liver proteins based...
An update on the mouse liver proteome (2009)
Background: Decoding of the liver proteome is subject of intense research, but hampered by methodological constraints. We recently developed an improved protocol for studying rat liver proteins based...
Epidermal growth factor (EGF) is an important mitogen for hepatocytes. Its targeted overexpression induced hepatocellular carcinomas (HCC), as recently reported by us (Borlak et al. 2005). Early...
Improved method for proteome mapping of the liver by 2-DE MALDI-TOF MS (2007)
Identifying the liver proteome has been the subject of intensified research. Notably, due to their strong heterogeneity in size, charge, solubility, and relative abundance, different strategies of...
Onkoproteomics von Lungentumoren (2006)
Chatterji, B., Ritorto, M.S., Garaguso, I., Belau, E., Gazzana, G., Borlak, J.
A map of the rat liver proteome: Abstract 35.4 (2005)
The number of proteins expressed in eukaryotic cells may vary between several thousands to half a million. Single hepatic cells express on average about 10,000 different proteins. Due to their strong...