Adenosine '-monophosphate, Beth Burnside, Michael Evans, R Theodore Fletcher, G J Chader
ABSTRACT In the teleost retina, the photoreceptors and retinal pigment epithelium (RPE) undergo extensive movements (called retinomotor movements) in response tochanges in light conditionsand to an...
Human Y-79 Retinoblastoma Cells Exhibit Specific Insulin Receptors. (2002)
Saviolakis,G. A., Kyritsis,A. P., Chader,G. J.
The presence of insulin receptors was investigated in human Y-79 retinoblastoma cells grown in suspension culture. The binding of 125I insulin to these cells was time-, temperature-, and...
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease. (1994)
Smith, M. A., Kutty, R. K., Richey, P. L., Yan, S. D., Stern, D., Chader, G. J., ...
Heme oxygenase-1 is an important enzyme that degrades heme, a pro-oxidant, leading to the formation of antioxidant molecules. In this study we demonstrate by immunocytochemistry close association of...
Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments
Rhee, S. G., Schoen, T., Chader, G. J., ...
Phototransduction in retinal rods involves a G protein-coupled signaling cascade that leads to cGMP hydrolysis and the closure of cGMP-gated cation channels that are open in darkness, producing a...
Kutty, R K, Kutty, G, Wiggert, B, Chader, G J, Darrow, R M, Organisciak, D T
The effect of intense visible light (light damage) on the expression of heme oxygenase 1 (HO-1), a protein induced by oxidative stress, was investigated in the rat retina. A sensitive reverse...
Steele, F R, Chader, G J, Johnson, L V, Tombran-Tink, J
Cultured pigment epithelial cells of the fetal human retina secrete a protein, pigment epithelium-derived factor (PEDF), that induces a neuronal phenotype in cultured human retinoblastoma cells....
Albini, A, Noonan, D M, Melchiori, A, Fassina, G F, Percario, M, Gentleman, S, ...
Gene and protein expression of Y-79 retinoblastoma cells growing on poly(D-lysine) is switched from a photoreceptor-like to a conventional neuron-like pathway by the basement membrane glycoprotein...
Interphotoreceptor retinoid-binding protein promotes rhodopsin regeneration in toad photoreceptors.
Okajima, T I, Pepperberg, D R, Ripps, H, Wiggert, B, Chader, G J
Interphotoreceptor retinoid-binding protein (IRBP) has been hypothesized to function as an intercellular shuttle in the vertebrate eye, serving to transport retinoids between the retinal pigment...
Jones, G J, Crouch, R K, Wiggert, B, Cornwall, M C, Chader, G J
After visual-pigment bleaching, single isolated rod photoreceptors of Ambystoma tigrinum recover their sensitivity to light when supplied with 11-cis-retinal from liposomes or with 11-cis-retinal...
Albini, A, Toffenetti, J, Zhu, Z, Chader, G J, Noonan, D M
The interphotoreceptor retinoid-binding protein (IRBP) is limited in expression to retinal photoreceptor cells and a subset of pinealocytes. We have obtained a genomic clone containing the entire...
Redmond, T M, Wiggert, B, Robey, F A, Chader, G J
Structural properties of the retinal extracellular-matrix glycolipoprotein interphotoreceptor retinoid-binding protein (IRBP) from human, monkey and bovine retinas have been compared....
Vitamin A receptors. Retinoic acid binding in ocular tissues.
Wiggert, B, Bergsma, D R, Helmsen, R, Chader, G J
Analysis of the sucrose-density-gradient patterns of the 110 000g supernatant fractions of adult and foetal retina and pigment epithelium showed them to contain a limited number of highly specific...
Identification of components of a phosphoinositide signaling pathway in retinal rod outer segments
Rhee, S. G., Schoen, T., Chader, G. J., ...
Phototransduction in retinal rods involves a G protein-coupled signaling cascade that leads to cGMP hydrolysis and the closure of cGMP-gated cation channels that are open in darkness, producing a...
Kutty, R K, Kutty, G, Wiggert, B, Chader, G J, Darrow, R M, Organisciak, D T
The effect of intense visible light (light damage) on the expression of heme oxygenase 1 (HO-1), a protein induced by oxidative stress, was investigated in the rat retina. A sensitive reverse...
Steele, F R, Chader, G J, Johnson, L V, Tombran-Tink, J
Cultured pigment epithelial cells of the fetal human retina secrete a protein, pigment epithelium-derived factor (PEDF), that induces a neuronal phenotype in cultured human retinoblastoma cells....
Albini, A, Noonan, D M, Melchiori, A, Fassina, G F, Percario, M, Gentleman, S, ...
Gene and protein expression of Y-79 retinoblastoma cells growing on poly(D-lysine) is switched from a photoreceptor-like to a conventional neuron-like pathway by the basement membrane glycoprotein...
Interphotoreceptor retinoid-binding protein promotes rhodopsin regeneration in toad photoreceptors.
Okajima, T I, Pepperberg, D R, Ripps, H, Wiggert, B, Chader, G J
Interphotoreceptor retinoid-binding protein (IRBP) has been hypothesized to function as an intercellular shuttle in the vertebrate eye, serving to transport retinoids between the retinal pigment...
Jones, G J, Crouch, R K, Wiggert, B, Cornwall, M C, Chader, G J
After visual-pigment bleaching, single isolated rod photoreceptors of Ambystoma tigrinum recover their sensitivity to light when supplied with 11-cis-retinal from liposomes or with 11-cis-retinal...
Albini, A, Toffenetti, J, Zhu, Z, Chader, G J, Noonan, D M
The interphotoreceptor retinoid-binding protein (IRBP) is limited in expression to retinal photoreceptor cells and a subset of pinealocytes. We have obtained a genomic clone containing the entire...
Redmond, T M, Wiggert, B, Robey, F A, Chader, G J
Structural properties of the retinal extracellular-matrix glycolipoprotein interphotoreceptor retinoid-binding protein (IRBP) from human, monkey and bovine retinas have been compared....
Vitamin A receptors. Retinoic acid binding in ocular tissues.
Wiggert, B, Bergsma, D R, Helmsen, R, Chader, G J
Analysis of the sucrose-density-gradient patterns of the 110 000g supernatant fractions of adult and foetal retina and pigment epithelium showed them to contain a limited number of highly specific...
Heme oxygenase-1 is associated with the neurofibrillary pathology of Alzheimer's disease.
Smith, M. A., Kutty, R. K., Richey, P. L., Yan, S. D., Stern, D., Chader, G. J., ...
Heme oxygenase-1 is an important enzyme that degrades heme, a pro-oxidant, leading to the formation of antioxidant molecules. In this study we demonstrate by immunocytochemistry close association of...
Tsokos, M., Kyritsis, A. P., Chader, G. J., Triche, T. J.
The capacity of a primitive human retinoblastoma cell line (Y-79) to differentiate into several cell types of normal human retina was investigated. Cells were studied in suspension and monolayer...
Newsome, D. A., Fletcher, R. T., Robison, W. G., Kenyon, K. R., Chader, G. J.
The effects of dibutyryl cyclic 3',5'-adenosine monophosphate (BcAMP) and Sephadex G-25 fractions of chick embryo extract on the growth rate, morphology, and pigmentation of normal chick retinal...