Essafi, A., Mattos, S.F. De, Hassen, Y.A.M., Soeiro, I., Mufti, G.J., Thomas, N.S.B., ...
In this study, we have used the human BV173 and the mouse BaF3/Bcr-Abl-expressing cell lines as model systems to investigate the molecular mechanisms whereby STI571 and FoxO3a regulate Bim expression...
Frequent expression of HAGE in presentation chronic myeloid leukaemias (2002)
Adams, S.P., Sahota, S.S., Mijovic, A., Czepulkowski, B., Padua, R.A., Mufti, G.J., ...
Cancer testis (CT) antigens provide attractive targets for cancer-specific immunotherapy. Although CT genes are expressed in some normal tissues, such as the testis and in some cases placenta, these...
Philpott-Howard, J. N., Wade, J. J., Mufti, G. J., Brammer, K. W., Ehniniger, G.
An open, randomized study was performed at 18 European centres to compare the efficacy, safety and tolerance of oral fluconazole with oral polyenes for the prophylaxis of fungal colonization and...
Philpott-Howard, J. N., Barker, K. F., Wade, J. J., Kaczmarski, R. S., Smedley, J. C., Mufti, G. J.
In a randomized multicentre study ciprofioxacin combined with aziocillin was compared with gentamicin and aziocillin for the treatment of febrile episodes in neutropenic patients. In 147 evaluable...
PAGLIUCA, A., MUFTI, G. J., JANOSSA-TAHERNIA, M., ERIDANI, S., WESTWOOD, N. B., THUMPSTON, J., ...
We have studied the prevalence of an underlying myeloproliferative state in 20 patients with either hepatic or portal vein thrombosis. Using conventional clinical and laboratory criteria, an...
Chronic Dialysis in Patients with Multiple Myeloma and Renal Failure: A Worthwhile Treatment (1989)
IGGO, N., PALMER, A.B.D., SEVERN, A., TRAFFORD, J.A.P., MUFTI, G.J., TAUBE, D., ...
Severe renal failure is a life-threatening complication of multiple myeloma. Aggressive treatment can reverse acute renal failure in many cases but the prognosis for those who require chronic renal...
Davison, F D, Kaczmarski, R S, Pozniak, A, Mufti, G J, Sutherland, S
Neutropenia induced by antiviral treatment, in particular AZT, can be improved with recombinant human granulocyte macrophage colony stimulating factor (RHGMCSF) in HIV positive patients. However,...
CD4+ lymphocytopenia due to common variable immunodeficiency mimicking AIDS.
Kaczmarski, R S, Webster, A D, Moxham, J, Davison, F, Sutherland, S, Mufti, G J
There are an increasing number of published reports of patients with acquired immunodeficiency without evidence of HIV infection, who have been labelled as having "idiopathic CD4+ lymphocytopenia"....
Lead poisoning: clinical, biochemical, and haematological aspects of a recent outbreak.
Pagliuca, A, Mufti, G J, Baldwin, D, Lestas, A N, Wallis, R M, Bellingham, A J
The clinical, biochemical, and haematological aspects of a recent outbreak of lead poisoning, in which exposure was related to the oxyacetylene cutting of red lead painted ironwork, were...
Cutaneous presentation of Fusarium solani infection in a bone marrow transplant recipient.
Child, F J, Fuller, L C, Higgins, E M, Du Vivier, A W, Mufti, G J
Davison, F D, Kaczmarski, R S, Pozniak, A, Mufti, G J, Sutherland, S
Neutropenia induced by antiviral treatment, in particular AZT, can be improved with recombinant human granulocyte macrophage colony stimulating factor (RHGMCSF) in HIV positive patients. However,...
CD4+ lymphocytopenia due to common variable immunodeficiency mimicking AIDS.
Kaczmarski, R S, Webster, A D, Moxham, J, Davison, F, Sutherland, S, Mufti, G J
There are an increasing number of published reports of patients with acquired immunodeficiency without evidence of HIV infection, who have been labelled as having "idiopathic CD4+ lymphocytopenia"....
Lead poisoning: clinical, biochemical, and haematological aspects of a recent outbreak.
Pagliuca, A, Mufti, G J, Baldwin, D, Lestas, A N, Wallis, R M, Bellingham, A J
The clinical, biochemical, and haematological aspects of a recent outbreak of lead poisoning, in which exposure was related to the oxyacetylene cutting of red lead painted ironwork, were...
Cutaneous presentation of Fusarium solani infection in a bone marrow transplant recipient.
Child, F J, Fuller, L C, Higgins, E M, Du Vivier, A W, Mufti, G J
Pyogenic abscesses in the myelodysplastic syndrome.
Williamson, P. J., Oscier, D. G., Mufti, G. J., Hamblin, T. J.
Acute transformation of a myeloproliferative state in sideroblastic anaemia with abnormal karyotype.
Reciprocal translocation between chromosomes 8 and 9 in atypical chronic myeloid leukaemia.
Oscier, D G, Mufti, G J, Gardiner, A, Hamblin, T J
A balanced translocation t(8;9) (p11;q34) was present in the peripheral blood, bone marrow, and spleen cells of a patient with Ph negative chronic myeloid leukaemia. Subsequent transformation into...
Abidi, S M, Griffiths, M, Oscier, D G, Mufti, G J, Hamblin, T J
A patient with Klinefelter's syndrome and diabetes mellitus was diagnosed as having myelodysplasia. Cytogenetic analysis of the peripheral blood and the bone marrow cells confirmed the presence of a...
Toxic shock syndrome complicated by laryngeal oedema.
Gatling, W., Mufti, G. J., McDonald, S. J.
A 50-year-old woman was admitted as an acute medical emergency and was diagnosed as having toxic shock syndrome. Thirty-six hours after admission she went into hepato-renal failure and had...
Exercise-induced urticaria and angio-oedema with relief from cromoglycate insufflation.
Hatty, S., Mufti, G. J., Hamblin, T. J.
The pathogenesis of physical urticarias is unknown and the treatment is often difficult and unsatisfactory. A patient with severe exercise-induced angio-oedema and urticaria is reported who responded...
Relapse of lymphoma in the heart after a 10-year remission.
Bell, A. J., Mufti, G. J., Hamblin, T. J.
A 71-year-old woman presented with intractable cardiac failure 10 years after receiving treatment for lymphoma. Extensive investigations failed to demonstrate a recurrence of her disease, but...
Bilateral adrenal lymphoma presenting as Addison's disease.
Pagliuca, A., Gillett, D. S., Salisbury, J. R., Basu, R. N., Mufti, G. J.
We describe an unusual case of non-Hodgkin's lymphoma of the adrenals which presented as Addison's disease. Examination of tissue taken by computed tomography guided biopsy revealed a high grade B...
Palmar-plantar erythema associated with combination chemotherapy.
Pagliuca, A., Kaczmarski, R., Mufti, G. J.
We report three cases of a distinctive palmar-plantar erythema associated with the treatment of non-Hodgkin's lymphoma and acute myeloid leukaemia. The rash is characterized by a painful, sharply...
Hollingsworth, S. J., Darling, D., Gäken, J., Hirst, W., Patel, P., Kuiper, M., ...
The recent use of interleukin 2 (IL-2) and interleukin 4 (IL-4) single cytokine modified tumour cells in rodent models has demonstrated a potential use of these cytokines to produce autologous cancer...