Scientific Commons: G. M.

G.M.

Portrait bust of Abraham Lincoln in plaster.

Targeting C-reactive protein for treatment of cardiovascular disease (2006)

Pepys,
M.B.,
Hirschfield,
G.M.,
Tennent,
G.A.,
...

Polyunsaturated fatty acids and neurotransmission in Caenorhabditis elegans (2006)

Marza,
E.,
Lesa,
G.M.

Changes in polyunsaturated fatty acid (PUFA) metabolism can cause mental retardation and cognitive impairment. However, it is still unclear why altered levels of PUFAs result in neuronal dysfunction....

The impact of HBV-DNA fluctuations on virus-specific CD8+ T cells in HBeAg+ Chronic Hepatitis B patients treated with a steroid and lamivudine (2006)

Gotto,
J.,
Webster,
G.J.M.,
Brown,
D.,
...

Teaching Film History through Film Production (2005)

PALETZ,
G.M

Trabalho apresentado no II Colóquio Brasil-Estados Unidos de Ciências da Comunicação, evento componente do XXVIII Congresso Brasileiro de Ciências da...

Teorias da comunicação: técnica, novas sociabilidades e mudanças culturais (2005)

FERREIRA,
G.M

Trabalho apresentado nas Mesas Temáticas do XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005 Nos estudos no...

DA IMAGEM À FOTOGRAFIA NO SUPORTE DE IMPRENSA: UM PERCURSO EM BUSCA DA DISCURSIVIDADE (2005)

FERREIRA,
G.M

Trabalho apresentado no NP01 - Teorias da Comunicação no XXVII Congresso Brasileiro de Ciências da Comunicação, Porto Alegre RS, 2004. Nosso objetivo neste...

Uma leitura dos estudos dos efeitos: da era das certezas às incertezas e mistérios da recepção (2005)

FERREIRA,
G.M

Trabalho apresentado no NP01 - Teorias da Comunicação no XXVIII Congresso Brasileiro de Ciências da Comunicação, Rio de Janeiro, RJ, 05-09,setembro,2005 Este...

E-jovens: potencialidades da escrita de si (2005)

NUSSBAUMER,
G.M

Trabalho apresentado no NP 13 - Comunicação e Cultura das Minorias no XXVII Congresso Brasileiro de Ciências da Comunicação, Porto Alegre RS, 2004. Neste texto...

O POSICIONAMENTO DISCURSIVO DA IMPRENSA: EM BUSCA DE UMA PROPOSTA METODOLÓGICA. (2005)

FERREIRA,
G.M

Trabalho apresentado no VII Colóquio Brasil-França de Ciências da ComunicaÃ§ão, evento componente do XXVII Congresso Brasileiro de Ciências da...

The constitutive secretion of serum albumin requires reversible protein tyrosine phosphorylation events in the trans-Golgi (2005)

Webb,
R.J.,
Judah,
J.D.,
Lo,
L.C.,
...

Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice (2005)

Hirschfield,
G.M.,
Gallimore,
J.R.,
Kahan,
M.C.,
...

Surfactant disaturated phosphatidylcholine kinetics in infants with bronchopulmonary dysplasia measured with stable isotopes and a two-compartment model (2005)

Cogo,
P.E.,
Toffolo,
G.M.,
Gucciardi,
A.,
...

We previously found a shorter surfactant disaturated phosphatidylcholine palmitate (DSPC-PA) half-life in infants with bronchopulmonary dysplasia (BPD) by using a single stable isotope tracer and...

Three or more copies of the proteolipid protein gene PLP1 cause severe Pelizaeus-Merzbacher disease (2005)

Wolf,
N.I.,
Sistermans,
E.A.,
Cundall,
M.,
...

Three or more copies of the proteolipid protein gene PLP1 is associated with a severe form of Pelizaeus-Merzbacher disease. (2005)

Wolf,
N.,
Sistermans,
E.A.,
Cundall,
M.,
...

We describe five boys from different families with an atypically severe form of Pelizaeus-Merzbacher disease (PMD) who have three, and in one case, five copies of the proteolipid protein (PLP1) gene....

Heterogeneous duplications in patients with Pelizaeus-Merzbacher disease suggest a mechanism of coupled homologous and nonhomologous recombination (2005)

Woodward,
K.J.,
Cundall,
M.,
Sperle,
K.,
...

We describe genomic structures of 59 X-chromosome segmental duplications that include the proteolipid protein 1 gene (PLP1) in patients with Pelizaeus-Merzbacher disease. We provide the first report...

Pediatric liver transplantation using segmental grafts from controlled non-heart beating donors (2005)

Muiesan,
P.,
Jassem,
W.,
Girlanda,
R.,
...

Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability (2005)

Clapp,
B.R.,
Hirschfield,
G.M.,
Storry,
C.,
...

BACKGROUND: Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when...

Issues in the development of cross-cultural assessments of speech and language for children (2005)

Carter,
J.A.,
Lees,
J.A.,
Murira,
G.M.,
...

Background: There is an increasing demand for the assessment of speech and language in clinical and research situations in countries where there are few assessment resources. Due to the nature of...

Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis (2005)

Broderick,
C.A.,
Smith,
A.J.,
Balaggan,
K.S.,
...

Autoimmune posterior uveitis is a chronic, potentially blinding inflammatory disease of the eye. It is commonly treated with immunosuppressive drugs that have adverse long-term effects. Advances in...

Normal lytic granule secretion by cytotoxic T lymphocytes deficient in BLOC-1, -2 and -3 and myosins Va, VIIa and XV (2005)

Bossi,
G.,
Booth,
S.,
Clark,
R.,
...

Melanocytes and cells of the immune system share an unusual secretory mechanism which uses the lysosome as a regulated secretory organelle. Recently, a number of the proteins required for these...

Effect of steroidal and non-steroidal drugs on the microglia activation pattern and the course of degeneration in the retinal degeneration slow mouse (2005)

Sarra,
G.M.,
Sarra,
F.G.,
Schlichtenbrede,
F.C.,
...

BACKGROUND: In hereditary retinal degeneration, microglia cells become activated, migrate through the outer nuclear layer (ONL) and accumulate in the subretinal space. Although this inflammatory...

Local administration of an adeno-associated viral vector expressing IL-10 reduces monocyte infiltration and subsequent photoreceptor damage during experimental autoimmune uveitis (2005)

Broderick,
C.A.,
Smith,
A.J.,
Balaggan,
K.S.,
...

Autoimmune posterior uveitis is a chronic, potentially blinding inflammatory disease of the eye. It is commonly treated with immunosuppressive drugs that have adverse long-term effects. Advances in...

Primordial Density Perturbation in Effective Loop Quantum Cosmology (2005)

Hossain,
G. M.

It is widely believed that a quantum field fluctuation in an inflating background creates the primeval seed perturbation which through subsequent evolution leads to the observed large-scale structure...

Full Length Research Paper - Analysis of genetic structure in Melia volkensii (Gurke.) populations using random amplified polymorphic DNA (2004)

Runo,
M.S.,
Muluvi,
G.M.,
D.W. Odee

Melia volkensii (Gurke.) is a popular fast growing agro forestry tree species in the East Africa's arid and semi arid lands (ASALs). The species is valued for its high quality termite resistant...

Implicit processing of global information in Balint's Syndrome (2004)

Jackson,
G.M.,
Swainson,
R.,
Mort,
D.,
...

Evolution of hepatitis B virus during primary infection in humans: transient generation of cytotoxic T-cell mutants. (2004)

Whalley,
S.A.,
Brown,
D.,
Webster,
G.J.,
...

Preprocedural inflammatory markers do not predict restenosis after successful coronary stenting (2004)

Gomma,
A.H.,
Hirschfield,
G.M.,
Gallimore,
J.R.,
...

Polycystic ovary syndrome, diabetes and cardiovascular disease:risks and risk factors. (2004)

Lakhani,
K.,
Prelevic,
G.M.,
Seifalian,
A.M.,
...

Local area deprivation and urban-rural differences in anxiety and depression among people older than 75 years in Britain (2004)

Walters,
K.,
Breeze,
E.,
Wilkinson,
P.,
...

Infrared spectroscopy of silicate glasses with application to natural systems (2004)

King,
P.L.,
McMillan,
P.F.,
Moore,
G.M.

In ovarian neoplasms, BRAF, but not KRAS, mutations are restricted to low-grade serous tumours. (2004)

Sieben,
N.L.,
Macropoulos,
P.,
Roemen,
G.M.,
...

Hepatitis C and treatment with pegylated interferon and ribavirin. (2004)

Gotto,
J.,
Dusheiko,
G.M.

High resolution analysis of cellular immune responses in resolved and persistent hepatitis C virus infection. (2004)

Lauer,
G.M.,
Barnes,
E.,
Lucas,
M.,
...

HSV shedding. (2004)

Sacks,
S.L.,
Griffiths,
P.D.,
Corey,
L.,
...

HSV-2 transmission. (2004)

Sacks,
S.L.,
Griffiths,
P.D.,
Corey,
L.,
...

Introduction: Is viral shedding a surrogate marker for transmission of genital herpes? (2004)

Sacks,
S.L.,
Griffiths,
P.D.,
Corey,
L.,
...

Lessons from HIV and hepatitis viruses. (2004)

Sacks,
S.L.,
Griffiths,
P.D.,
Corey,
L.,
...

PHOX2B mutations and polyalanine expansions correlate with the severity of the respiratory phenotype and associated symptoms in both congenital and late onset Central Hypoventilation syndrome (2004)

Matera,
I.,
Bachetti,
T.,
Puppo,
F.,
...

KCNQ/M currents in sensory neurons: significance for pain therapy (2003)

Passmore,
G.M.,
Selyanko,
A.A.,
Mistry,
M.,
...

Neuronal hyperexcitability is a feature of epilepsy and both inflammatory and neuropathic pain. M currents [IK(M)] play a key role in regulating neuronal excitability, and mutations in neuronal...

Generation of activated sialoadhesin-positive microglia during retinal degeneration (2003)

Hughes,
E.H.,
Schlichtenbrede,
F.C.,
Murphy,
C.C.,
...

PURPOSE: The retina contains a rich network of myeloid-derived cells (microglia) within the retinal parenchyma and surrounding vessels. Their response and behavior during inflammation and...

Recombinant human elastin polypeptides self-assemble into biomaterials with elastin-like properties. (2003)

Bellingham,
C.M.,
Lillie,
M.A.,
Gosline,
J.M.,
...

3-year prospective multicenter study on one-stage implant surgery and early loading in the edentulous mandible (2003)

Raghoebar,
G.M.,
Friberg,
B.,
Grunert,
I.,
...

The effects of transdermal estradiol alone or with cyclical dydrogesterone on markers of cardiovascular disease risk in postmenopausal women with type 2 diabetes: A pilot study (2003)

Stojanovic,
N.D.,
Kwong,
P.,
Byrne,
D.J.,
...

Tracking the source of the hepatitis B virus-specific CD8 T cells during lamivudine treatment (2003)

Malacarne,
F.,
Webster,
G.J.,
Reignat,
S.,
...

Why parents of children with neurodevelopmental disabilities requiring gastrostomy feeding need more support (2003)

Craig,
G.M.,
Scambler,
G.,
Spitz,
L.

Polyunsaturated fatty acids are required for efficient neurotransmission in C. elegans (2003)

Lesa,
G.M.,
Palfreyman,
M.,
Hall,
D.H.,
...

The complex lipid constituents of the eukaryotic plasma membrane are precisely controlled in a cell-type-specific manner, suggesting an important, but as yet, unknown cellular function. Neuronal...

Executive function profile of children with Attention Deficit Hyperactivity Disorder (2002)

Shallice,
T.,
Marzocchi,
G.M.,
Coser,
S.,
...

Brain anatomy and sensorimotor gating in Asperger's syndrome. (2002)

McAlonan,
G.M.,
Daly,
E.,
Kumari,
V.,
...

Elastic scattering spectroscopy for intraoperative detection of sentinel lymph node metastasis (2002)

Lee,
A.C.,
Pickard,
C.D.O.,
Briggs,
G.M.,
...

Elastic scattering spectroscopy for the diagnosis of breast cancer (2002)

Lee,
A.C.,
Pickard,
C.D.O.,
Keshtgar,
M.R.S.,
...

Intraoperative assessment by optical biopsy for lymph node metastasis in breast cancer (2002)

Lee,
A.C.,
Pickard,
C.D.O.,
Keshtgar,
M.R.S.,
...

Optical biopsy: The technique and experience in determining lymph node status in breast cancer (2002)

Keshtgar,
M.R.S.,
Lee,
A.C.,
Pickard,
C.D.P.,
...

Antibody and radionuclide characteristics and the enhancement of the effectiveness of radioimmunotherapy by selective dose delivery to radiosensitive areas of tumour (2002)

Flynn,
A.A.,
Pedley,
R.B.,
Green,
A.J.,
...

Purpose: Estimating the absorbed dose to tumour relative to normal tissues has often been used in the assessment of the therapeutic efficacy of radiolabelled antibodies for radioimmuno-therapy....

Interferon : biology, pharmacology and therapy for chronic viral hepatitis (2002)

Dusheiko,
G.M.

Equivalence of three or four cycles of bleomycin, etoposide, and cisplatin chemotherapy and of a 3- or 5-day schedule in good-prognosis germ cell cancer: a randomized study of the European Organization for Research and Treatment of Cancer Genitourinary Tr (2001)

De Wit,
R.,
Roberts,
J.T.,
Wilkinson,
P.M.,
...

C-reactive protein and its role in the pathogenesis of myocardial infarction (2001)

Pepys,
M.B.,
Hirschfield,
G.M.

C-reactive protein (CRP), the classical acute phase reactant, has for some time contributed to both the diagnosis and management of a wide range of infective and inflammatory conditions. More...

C-reactive protein and atherothrombosis (2001)

Pepys,
M.B.,
Hirschfield,
G.M.

Circulating concentrations of C-reactive protein (CRP), the classical acute phase protein and sensitive systemic marker of inflammation, significantly predict atherothrombotic events and outcome...

Gene replacement therapy in the retinal degeneration slow (rds) mouse: the effect on retinal degeneration following partial transduction of the retina (2001)

Sarra,
G.M.,
Stephens,
C.,
De Alwis,
M.,
...

The retinal degeneration slow (rds or Prph2(Rd2/Rd2)) mouse, a model of recessive retinitis pigmentosa, lacks a functional gene encoding peripherin 2. This membrane glycoprotein is required for the...

Phosphatidylinositol transfer proteins and protein kinase C make separate but non-interacting contributions to the phosphorylation state necessary for secretory competence in rat mast cells (2001)

Pinxteren,
J.A.,
Gomperts,
B.D.,
Rogers,
D.,
...

Mast cells permeabilized by streptolysin O undergo exocytosis when stimulated with Ca(2+) and guanosine 5'-[gamma-thio]triphosphate but become progressively refractory to this stimulus if it is...

A quantitative assessment of protoporphyrin IX metabolism and phototoxicity in human skin following dose-controlled delivery of the prodrugs 5-aminolaevulinic acid and 5-aminolaevulinic acid-n-pentylester (2001)

Gerscher,
S.,
Connelly,
J.P.,
Beijersbergen Van Henegouwen,
G.M.,
...

The timing, triggers and qualities of recovered memories in therapy. (2000)

Andrews,
B.,
Brewin,
C.R.,
Ochera,
J.,
...

Thin Ta205Films Deposited by Photo-Induced Chemical Vapour Desposition Using and Injection Liquid Source (2000)

Zhang,
J.Y.,
Boyd,
I.W.,
Mooney,
M.B.,
...

Radioimmunoguided surgery in colorectal cancer using a genetically engineered anti-CEA single-chain Fv antibody (2000)

Mayer,
A.,
Tsiompanou,
E.,
O'Malley,
D.,
...

In radioimmunoguided surgery (RIGS), a radiolabeled antibody is given i.v. before surgery and a hand-held gamma-detecting probe is used to locate tumor in the operative field. The rapid blood...

Chronological change in natural killer (NK) cell frequency, during pre-clinical phase of acute hepatitis B infection (2000)

Webster,
G.J.M.,
Rana,
H.,
Whalley,
S.A.,
...

Diagnosis of acute and chronic hepatitis C (2000)

Brown,
D.,
Manalakopoulos,
S.,
Dusheiko,
G.M.

Characteristics, context and consequences of memory recovery among adults in therapy. (1999)

Andrews,
B.,
Brewin,
C.R.,
Ochera,
J.,
...

Prognostic factors in patients progressing after cisplatin based chemotherapy for malignant non-seminomatous germ cell tumours (1999)

Fossa,
S.D.,
Stenning,
S.P.,
Gerl,
A.,
...

The aim of this study was to define prognostic parameters for survival in patients with malignant germ cell tumours progressing after platinum-based induction chemotherapy with or without surgery. A...

Recovered memories in theory and practice (1998)

Davies,
G.M.,
Morton,
J.,
Mollon,
P.,
...

Radioimmunoguided surgery (RIGS) of colorectal cancer with single chain Fv antibody to CEA (1998)

Boxer,
G.M.,
Mayer,
A.,
O'Malley,
D.,
...

Influence of HIV-1 Infection of GBV-C Infection in Multiply Infected Haemophilic Patients (1998)

Devereux,
H.,
Sabin,
C.A.,
Kinson,
Z.,
...

Biodistribution, stability and antiviral efficacy of liposome-entrapped phosphorothiolate antisense oligonucleotide in ducks for the treatment of chronic duck hepatitis B virus infection (1998)

Soni,
P.N.,
Brown,
D.,
Saffie,
R.,
...

Hepatitis C virus (HCV) tends to associate preferentially with high-density lipoproteins by standard ultracentrifugal fractionation of plasma from patients with chronic HCV infection (1998)

Manzini,
P.,
Dusheiko,
G.M.,
Brown,
D.,
...

Radioimmunoguided surgery (RIGS) of colorectal cancer with single chain Fv antibody to CEA (1997)

Boxer,
G.M.,
Mayer,
A.,
OMalley,
D.,
...

Exemplifying guidelines for preparation of recombinant DNA products in phase I trials in cancer: Preparation of a genetically engineered anti-CEa single chain Fv antibody (1997)

Mayer,
A.,
Chester,
K.A.,
Bhatia,
J.,
...

Products of recombinant DNA technology have potential for the diagnosis or treatment of cancer. There is a need to investigate whether they function by the intended mechanism in small phase I...

Lymphocyte and macrophage phenotype in chronic hepatitis C infection - Correlation with disease activity (1997)

Khakoo,
S.I.,
Soni,
P.N.,
Savage,
K.,
...

Oral Mycobacterium avium complex infection in a patient with HIV-related disease - a case-report (1996)

Robinson,
P.,
Farthing,
P.,
Scott,
G.M.,
...

The behavioural treatment of verbal interaction skills following severe head injury: A single case study (1988)

Giles,
G.M.,
Fussey,
I.,
Burgess,
P.W.

Behavioral treatment of attention deficits in mentally impaired subjects (1987)

Burgess,
P.W.,
Mitchelmore,
S.,
Giles,
G.M.

G. M.

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