G. M. Briggs

Publication List Details

Period

1991 - 1998

Number

12

Co-Authors

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium.

Gwathmey, J K, Slawsky, M T, Hajjar, R J, Briggs, G M, Morgan, J P

Experiments were performed in human working myocardium to investigate the relationship of intracellular calcium handling and availability to alterations in the strength of contraction produced by...

Diastolic dysfunction in hypertrophic cardiomyopathy. Effect on active force generation during systole.

Gwathmey, J K, Warren, S E, Briggs, G M, Copelas, L, Feldman, M D, Phillips, P J, ...

We tested the hypothesis that intracellular Ca++ [( Ca++]i) overload underlies the diastolic dysfunction of patients with hypertrophic cardiomyopathy. Myocardial tissue was obtained at the time of...

Differential effect of DPI 201-106 on the sensitivity of the myofilaments to Ca2+ in intact and skinned trabeculae from control and myopathic human hearts.

Hajjar, R J, Gwathmey, J K, Briggs, G M, Morgan, J P

The effects of DPI, a new inotropic agent, were compared in trabeculae carneae from control and myopathic human hearts loaded with aequorin, a bioluminescent calcium indicator that emits light when...

Role of intracellular sodium in the regulation of intracellular calcium and contractility. Effects of DPI 201-106 on excitation-contraction coupling in human ventricular myocardium.

Gwathmey, J K, Slawsky, M T, Briggs, G M, Morgan, J P

Experiments were performed to investigate the mechanism of action of DPI 201-106 on human heart muscle. In both control and myopathic muscles, DPI produced concentration-dependent increases in action...

Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium.

Gwathmey, J K, Slawsky, M T, Hajjar, R J, Briggs, G M, Morgan, J P

Experiments were performed in human working myocardium to investigate the relationship of intracellular calcium handling and availability to alterations in the strength of contraction produced by...

Diastolic dysfunction in hypertrophic cardiomyopathy. Effect on active force generation during systole.

Gwathmey, J K, Warren, S E, Briggs, G M, Copelas, L, Feldman, M D, Phillips, P J, ...

We tested the hypothesis that intracellular Ca++ [( Ca++]i) overload underlies the diastolic dysfunction of patients with hypertrophic cardiomyopathy. Myocardial tissue was obtained at the time of...

Differential effect of DPI 201-106 on the sensitivity of the myofilaments to Ca2+ in intact and skinned trabeculae from control and myopathic human hearts.

Hajjar, R J, Gwathmey, J K, Briggs, G M, Morgan, J P

The effects of DPI, a new inotropic agent, were compared in trabeculae carneae from control and myopathic human hearts loaded with aequorin, a bioluminescent calcium indicator that emits light when...

Role of intracellular sodium in the regulation of intracellular calcium and contractility. Effects of DPI 201-106 on excitation-contraction coupling in human ventricular myocardium.

Gwathmey, J K, Slawsky, M T, Briggs, G M, Morgan, J P

Experiments were performed to investigate the mechanism of action of DPI 201-106 on human heart muscle. In both control and myopathic muscles, DPI produced concentration-dependent increases in action...