G. M. Hirschfield

Publication List Details

Period

2003 - 2008

Number

11

Co-Authors

Transgenic human CRP is not pro-atherogenic, pro-atherothrombotic or pro-inflammatory in apoE−/− mice (2008)

Tennent, G.A., Hutchinson, W.L., Kahan, M.C., Hirschfield, G.M., Gallimore, J.R., Lewin, J., ...

The pathogenic significance, if any, of the epidemiological association between baseline C-reactive protein (CRP) values and future atherothrombotic events is not known. We therefore investigated...

Targeting C-reactive protein for the treatment of cardiovascular disease (2006)

Pepys, M.B., Hirschfield, G.M., Tennent, G.A., Gallimore, J.R., Kahan, M.C., Bellotti, V., ...

Complement-mediated inflammation exacerbates the tissue injury of ischaemic necrosis in heart attacks and strokes, the most common causes of death in developed countries. Large infarct size increases...

Targeting C-reactive protein for the treatment of cardiovascular disease (2006)

Pepys, M.B., Hirschfield, G.M., Tennent, G.A., Gallimore, J.R., Kahan, M.C., Bellotti, V., ...

Complement-mediated inflammation exacerbates the tissue injury of ischaemic necrosis in heart attacks and strokes, the most common causes of death in developed countries. Large infarct size increases...

Letter. Targeting C-reactive protein for the treatment of cardiovascular disease (2006)

Pepys, M.B., Hirschfield, G.M., Tennent, G.A., Gallimore, J.R., Kahan, M.C., Bellotti, V., ...

Complement-mediated inflammation exacerbates the tissue injury of ischaemic necrosis in heart attacks and strokes, the most common causes of death in developed countries. Large infarct size increases...

Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice (2005)

Hirschfield, G.M., Gallimore, J.R., Kahan, M.C., Hutchinson, W.L., Sabin, C.A., Benson, G.M., ...

The association between circulating concentrations of C-reactive protein (CRP) and future atherothrombotic events has provoked speculation about a possible pathogenetic role of CRP. However, we show...

Transgenic human C-reactive protein is not proatherogenic in apolipoprotein E-deficient mice (2005)

Hirschfield, G.M., Gallimore, J.R., Kahan, M.C., Hutchinson, W.L., Sabin, C.A., Benson, G.M., ...

The association between circulating concentrations of C-reactive protein (CRP) and future atherothrombotic events has provoked speculation about a possible pathogenetic role of CRP. However, we show...

Inflammation and endothelial function: direct vascular effects of human C-reactive protein on nitric oxide bioavailability (2005)

Clapp, B.R., Hirschfield, G.M., Storry, C., Gallimore, J.R., Stidwill, R.P., Singer, M., ...

Background: Circulating concentrations of the sensitive inflammatory marker C-reactive protein (CRP) predict future cardiovascular events, and CRP is elevated during sepsis and inflammation, when...

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease (2004)

Danesh, J., Wheeler, J.G., Hirschfield, G.M., Eda, S., Eiriksdottir, G., Rumley, A., ...

BACKGROUND: C-reactive protein is an inflammatory marker believed to be of value in the prediction of coronary events. We report data from a large study of C-reactive protein and other circulating...

C-reactive protein and cardiovascular disease: new insights from an old molecule (2003)

Hirschfield, G.M., Pepys, M.B.

The classical acute-phase protein, C-reactive protein (CRP), is an exquisitely sensitive systemic marker of disease with broad clinical utility for monitoring and differential diagnosis....

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

Danesh, J., Wheeler, J.G., Hirschfield, G.M., Eda, S., Eiriksdottir, G., Rumley, A., ...

BACKGROUND: C-reactive protein is an inflammatory marker believed to be of value in the prediction of coronary events. We report data from a large study of C-reactive protein and other circulating...

C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease

Danesh, J., Wheeler, J.G., Hirschfield, G.M., Eda, S., Eiriksdottir, G., Rumley, A., ...

BACKGROUND: C-reactive protein is an inflammatory marker believed to be of value in the prediction of coronary events. We report data from a large study of C-reactive protein and other circulating...