G. Opdenakker

Publication List Details

Period

1987 - 2007

Number

34

Co-Authors

Peptidoglycan from sterile human spleen induces T-cell proliferation and inflammatory mediators in rheumatoid arthritis patients and healthy subjects (2001)

Schrijver, I.A., Melief, M.J., Markusse, H.M., Aelst, I. Van, Opdenakker, G., Hazenberg, M.P., ...

OBJECTIVES: Peptidoglycan (PG), a component of Gram-positive bacteria, may be involved in rheumatoid arthritis (RA) because of its ability to induce production of proinflammatory cytokines, to induce...

Peptidoglycan from sterile human spleen induces T-cell proliferation and inflammatory mediators in rheumatoid arthritis patients and healthy subjects (2001)

Schrijver, I. A., Markusse, H. M., Van Aelst, I., Opdenakker, G., Hazenberg, M. P., ...

Objectives. Peptidoglycan (PG), a component of Gram‐positive bacteria, may be involved in rheumatoid arthritis (RA) because of its ability to induce production of...

The cytokine-protease connection: identification of a 96-kD THP-1 gelatinase and regulation by interleukin-1 and cytokine inducers. (1991)

Van Ranst, M, Norga, K, Masure, S, Proost, P, Vandekerckhove, F, Auwerx, J, ...

The induction of proteolytic enzymes is an important mechanism in the migration of monocytes into tissues and body fluids. The monocytic cell line THP-1 was used as a model system to study the...

Determination of tissue-type plasminogen-activator mRNA in human and non-human cell lines by dot-blot hybridization.

Opdenakker, G, Billiau, A, Volckaert, G, De Somer, P

A labelled cDNA clone was used in DNA-RNA hybridization on nitrocellulose filter paper (dot-blot technique) to detect and quantify mRNA for endogenous tissue plasminogen activator (PA) in cell...

The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans.

Jaques, A J, Opdenakker, G, Rademacher, T W, Dwek, R A, Zamze, S E

The glycosylation of tissue plasminogen activator (t-PA) obtained from the Bowes melanoma cell line was re-examined using methods of serial lectin affinity chromatography coupled with Bio-Gel P-4 gel...

Human tissue-type plasminogen activator gene located near chromosomal breakpoint in myeloproliferative disorder.

Yang-Feng, T L, Opdenakker, G, Volckaert, G, Francke, U

Plasminogen activators (PA) convert the inactive proenzyme plasminogen into plasmin, which is involved in the process of fibrinolysis, tissue remodeling, and cell migration. There are two distinct...

Determination of tissue-type plasminogen-activator mRNA in human and non-human cell lines by dot-blot hybridization.

Opdenakker, G, Billiau, A, Volckaert, G, De Somer, P

A labelled cDNA clone was used in DNA-RNA hybridization on nitrocellulose filter paper (dot-blot technique) to detect and quantify mRNA for endogenous tissue plasminogen activator (PA) in cell...

The glycosylation of Bowes melanoma tissue plasminogen activator: lectin mapping, reaction with anti-L2/HNK-1 antibodies and the presence of sulphated/glucuronic acid containing glycans.

Jaques, A J, Opdenakker, G, Rademacher, T W, Dwek, R A, Zamze, S E

The glycosylation of tissue plasminogen activator (t-PA) obtained from the Bowes melanoma cell line was re-examined using methods of serial lectin affinity chromatography coupled with Bio-Gel P-4 gel...

Human tissue-type plasminogen activator gene located near chromosomal breakpoint in myeloproliferative disorder.

Yang-Feng, T L, Opdenakker, G, Volckaert, G, Francke, U

Plasminogen activators (PA) convert the inactive proenzyme plasminogen into plasmin, which is involved in the process of fibrinolysis, tissue remodeling, and cell migration. There are two distinct...

Expression of gelatinase B and the extracellular matrix metalloproteinase inducer EMMPRIN in benign and malignant pigment cell lesions of the skin.

Van Den Oord, J. J., Paemen, L., Opdenakker, G.

By the degradative effect on basement membrane collagen type IV, matrix metalloproteinases (MMPs) or gelatinases are important in the early invasion of malignant tumors. These enzymes may be released...

Expression of gelatinase B in trachomatous conjunctivitis

El-Asrar, A., Geboes, K., Al-Kharashi, S., Al-Mosallam, A., Missotten, L., Paemen, L., ...

BACKGROUND/AIMS—Gelatinase B is a matrix metalloproteinase involved in extracellular matrix (ECM) breakdown often associated with scarring and other pathological disorders. It was investigated...

Pyrogenic and haematological effects of the interferon-inducing 22K factor (interleukin 1 beta) from human leukocytes.

Van Damme, J, Opdenakker, G, De Ley, M, Heremans, H, Billiau, A

Human 22K factor is a cytokine released by mitogen-stimulated peripheral blood leukocytes. The factor stimulates fibroblasts to produce interferon-beta (IFN-beta) and thereby exerts antiviral...