Buruli ulcer disease: prospects for a vaccine (2009)
Huygen, K., Adjei, O., Affolabi, D., Bretzel, G., Demangel, C., Fleisher, B., ...
Buruli ulcer disease (BUD), caused by Mycobacterium ulcerans, is a neglected bacterial infection of the poor in remote rural areas, mostly affecting children. BUD is a mutilating disease leading to...
Ongoing genome reduction in Mycobacterium ulcerans (2007)
Rondini, S., Käser, M., Stinear, T., Tessier, M., Mangold, C., Dernick, G., ...
Elucidation of the transmission, epidemiology, and evolution of Mycobacterium ulcerans, the causative agent of Buruli ulcer, is hampered by the striking lack of genetic diversity of this emerging...
Hilty, M., Yeboah-Manu, D., Boakye, D., Mensah-Quainoo, E., Rondini, S., Schelling, E., ...
The molecular typing methods used so far for Mycobacterium ulcerans isolates have not been able to identify genetic differences among isolates from Africa. This apparent lack of genetic diversity...
Buruli ulcer (M. ulcerans infection): new insights, new hope for disease control (2005)
Johnson, P. D. R., Stinear, T., Small, P. L. C., Pluschke, G., Merritt, R. W., Portaels, F., ...
Buruli ulcer is now emerging from long years of neglect: interest and momentum are growing. However, there is much to do if we are to understand why the disease is becoming more common and how this...
Buruli ulcer disease in Cameroon rediscovered (2004)
Noeske, J., Kuaban, C., Rondini, S., Sorlin, P., Ciaffi, L., Mbuagbaw, J., ...
To assess the magnitude of the Buruli ulcer (BU) problem in Cameroon, we conducted a cross-sectional survey in the Nyong River basin and identified on clinical grounds a total of 436 cases of active...
Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan.
Pluschke, G, Vanek, M, Evans, A, Dittmar, T, Schmid, P, Itin, P, ...
A human melanoma-associated chondroitin sulfate proteoglycan (MCSP), recognized by mAb 9.2.27, plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading...
Development and Application of Real-Time PCR Assay for Quantification of Mycobacterium ulcerans DNA
Rondini, S., Mensah-Quainoo, E., Troll, H., Bodmer, T., Pluschke, G.
Buruli ulcer, an infection caused by Mycobacterium ulcerans, is, after tuberculosis and leprosy, the third most common mycobacterial disease. The mode of transmission of M. ulcerans is not exactly...
Humoral and cellular defense against intestinal murine infection with Yersinia enterocolitica.
Hanski, C, Naumann, M, Grützkau, A, Pluschke, G, Friedrich, B, Hahn, H, ...
The role of phagocytes and the complement system as potential host defense mechanisms against bacterial infection were studied in mice with two isogenic strains of Yersinia enterocolitica serotype O8...
A reexamination of the O1 lipopolysaccharide antigen group of Escherichia coli.
Moll, A, Kusecek, B, Pluschke, G, Morelli, G, Kamke, M, Jann, B, ...
A total of 64 Escherichia coli strains of the O1 serogroup were tested for the migration pattern of their lipopolysaccharides (LPS) on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. O1:K1...
Pluschke, G, Moll, A, Kusecek, B, Achtman, M
The lipopolysaccharide (LPS) of Escherichia coli O18 isolated from a wide variety of sources was analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Four different LPS...
Monoclonal IgM specific for the O18 antigen conferred passive protection to 1-week-old rats against bacteremia and killing after oral challenge with O18:K1 Escherichia coli. Specific protection of...
Kusecek, B, Wloch, H, Mercer, A, Vaisänen, V, Pluschke, G, Korhonen, T, ...
K1, K5, and K100 Escherichia coli isolates of the lipopolysaccharide antigen types O1, O7, O16, O18, or O75, which had formerly been assigned to clonal groupings were compared with K? E. coli...
A total of 95 K1 Escherichia coli strains of the O (lipopolysaccharide) serotypes O1, O7, or O18 had been analyzed previously for the ability to cause bacteremia after colonizing the gut of newborn...
Pluschke, G, Mayden, J, Achtman, M, Levine, R P
Epidemiological data show that O18:K1 Escherichia coli is a common cause of neonatal bacteremia and meningitis. These bacteria were capable of multiplying in the bloodstream of newborn rats and were...
Pluschke, G, Mercer, A, Kusećek, B, Pohl, A, Achtman, M
A total of 95 Escherichia coli strains (O1:K1, O7:K1, or O18:K1), obtained from different sources of human infections and from healthy individuals, were analyzed for the ability to cause bacteremia...
Molecular cloning of a human melanoma-associated chondroitin sulfate proteoglycan.
Pluschke, G, Vanek, M, Evans, A, Dittmar, T, Schmid, P, Itin, P, ...
A human melanoma-associated chondroitin sulfate proteoglycan (MCSP), recognized by mAb 9.2.27, plays a role in stabilizing cell-substratum interactions during early events of melanoma cell spreading...
Development and Application of Real-Time PCR Assay for Quantification of Mycobacterium ulcerans DNA
Rondini, S., Mensah-Quainoo, E., Troll, H., Bodmer, T., Pluschke, G.
Buruli ulcer, an infection caused by Mycobacterium ulcerans, is, after tuberculosis and leprosy, the third most common mycobacterial disease. The mode of transmission of M. ulcerans is not exactly...
Humoral and cellular defense against intestinal murine infection with Yersinia enterocolitica.
Hanski, C, Naumann, M, Grützkau, A, Pluschke, G, Friedrich, B, Hahn, H, ...
The role of phagocytes and the complement system as potential host defense mechanisms against bacterial infection were studied in mice with two isogenic strains of Yersinia enterocolitica serotype O8...
A reexamination of the O1 lipopolysaccharide antigen group of Escherichia coli.
Moll, A, Kusecek, B, Pluschke, G, Morelli, G, Kamke, M, Jann, B, ...
A total of 64 Escherichia coli strains of the O1 serogroup were tested for the migration pattern of their lipopolysaccharides (LPS) on sodium dodecyl sulfate-polyacrylamide gel electrophoresis. O1:K1...
Pluschke, G, Moll, A, Kusecek, B, Achtman, M
The lipopolysaccharide (LPS) of Escherichia coli O18 isolated from a wide variety of sources was analyzed by sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE). Four different LPS...
Monoclonal IgM specific for the O18 antigen conferred passive protection to 1-week-old rats against bacteremia and killing after oral challenge with O18:K1 Escherichia coli. Specific protection of...
Kusecek, B, Wloch, H, Mercer, A, Vaisänen, V, Pluschke, G, Korhonen, T, ...
K1, K5, and K100 Escherichia coli isolates of the lipopolysaccharide antigen types O1, O7, O16, O18, or O75, which had formerly been assigned to clonal groupings were compared with K? E. coli...
A total of 95 K1 Escherichia coli strains of the O (lipopolysaccharide) serotypes O1, O7, or O18 had been analyzed previously for the ability to cause bacteremia after colonizing the gut of newborn...
Pluschke, G, Mayden, J, Achtman, M, Levine, R P
Epidemiological data show that O18:K1 Escherichia coli is a common cause of neonatal bacteremia and meningitis. These bacteria were capable of multiplying in the bloodstream of newborn rats and were...
Pluschke, G, Mercer, A, Kusećek, B, Pohl, A, Achtman, M
A total of 95 Escherichia coli strains (O1:K1, O7:K1, or O18:K1), obtained from different sources of human infections and from healthy individuals, were analyzed for the ability to cause bacteremia...
Functional properties of rat immunoglobulins obtained from hybridoma isotype switch variants were studied in vivo in a rat model for neonatal bacterial sepsis. Escherichia coli 018:K1, a common cause...
Complete two-dimensional gel electrophoresis pattern of de novo synthesized acute phase reactants.
Pluschke, G, Jenni, L, Van Alphen, L, Lefkovits, I
The early stages of inflammatory responses are characterized by the rapid synthesis of a heterogenous group of plasma proteins known as acute phase reactants. We show that the complex changes in the...
Pöltl-Frank, F, Zurbriggen, R, Helg, A, Stuart, F, Robinson, J, Glück, R, ...
Immunopotentiating reconstituted influenza virosomes (IRIV) were used as a delivery system for the synthetic peptide-based malaria vaccine SPf66. The reduced SPf66 peptide molecules containing...