Gibson, PR, Weston, AR, Shann, A, Florin, THJ, Lawrance, IC, Macrae, FA, ...
Background and Aim: New treatments for Crohn's disease are expensive and place economic strain upon health-care systems, and 'value-for-money' needs to be confirmed. This study aimed to correlate...
Lee, N., Fowler, E., Mason, S., Lincoln, D., Taaffe, D. R., Radford-Smith, G.
Background and aim: There is limited consensus on the major variables that determine bone integrity and bone loss in patients with Crohn's disease. Twin and family studies in the general population...
Lee, N., Fowler, E., Mason, S., Lincoln, D., Taaffe, D. R., Radford-Smith, G.
Background and aim: There is limited consensus on the major variables that determine bone integrity and bone loss in patients with Crohn's disease. Twin and family studies in the general population...
Gibson, PR, Fixa, B, Pekarkova, B, Batovsky, M, Radford-Smith, G, Tibitanzl, J, ...
Background There are no comparative studies of coated mesalazine. Aim To compare the efficacy and tolerability of Eudragit-L- and ethylcellulose-coated mesalazine tablets in patients with mild to...
Hume, G. E., Fowler, E. V., Lincoln, D., Eri, R., Templeton, D., Florin, T. H., ...
Aims: Conduct an Australian-based analysis of the angiotensinogen-6 variant in two independent inflammatory bowel disease (IBD) cohorts, and examine the role of angiotensinogen-6 and TGFß1 codon 25...
Gibson, PR, Fixa, B, Pekarkova, B, Batovsky, M, Radford-Smith, G, Tibitanzl, J, ...
Background There are no comparative studies of coated mesalazine. Aim To compare the efficacy and tolerability of Eudragit-L- and ethylcellulose-coated mesalazine tablets in patients with mild to...
Hume, G. E., Fowler, E. V., Lincoln, D., Eri, R., Templeton, D., Florin, T. H., ...
Aims: Conduct an Australian-based analysis of the angiotensinogen-6 variant in two independent inflammatory bowel disease (IBD) cohorts, and examine the role of angiotensinogen-6 and TGFß1 codon 25...
B. G. Feagan, W. J. Sandborn, G. Lichtenstein, G. Radford-Smith, J. Patel, A. Innes
Background More than 50% of patients with Crohn's disease become either steroid resistant or dependent. Accordingly, development of new treatments for steroid-dependent Crohn's disease is a research...
Bone loss in Crohn's disease: Exercise as a potential countermeasure (2005)
Lee, N, Radford-Smith, G, Taaffe, DR
Crohn's disease (CD) is associated with a number of secondary conditions including osteoporosis, which increases the risk of bone fracture. The cause of metabolic bone disease in this Population is...
Bone loss in Crohn's disease: Exercise as a potential countermeasure (2005)
Lee, N, Radford-Smith, G, Taaffe, DR
Crohn's disease (CD) is associated with a number of secondary conditions including osteoporosis, which increases the risk of bone fracture. The cause of metabolic bone disease in this Population is...
The Role of Cytokines in Inflammatory Bowel Disease (1994)
G. Radford-Smith, D. P. Jewell
Cytokines play an important role in the development and persistence of the inflammatory lesions seen in Crohn's disease and ulcerative colitis. This review discusses the current thinking of the role...
Bone loss in Crohn's disease: Exercise as a potential countermeasure
Lee, N, Radford-Smith, G, Taaffe, DR
Crohn's disease (CD) is associated with a number of secondary conditions including osteoporosis, which increases the risk of bone fracture. The cause of metabolic bone disease in this Population is...
Gibson, PR, Fixa, B, Pekarkova, B, Batovsky, M, Radford-Smith, G, Tibitanzl, J, ...
Background There are no comparative studies of coated mesalazine. Aim To compare the efficacy and tolerability of Eudragit-L- and ethylcellulose-coated mesalazine tablets in patients with mild to...
Morphology of sporadic colorectal cancer with DNA replication errors
Jass, J, Do, K, Simms, L, Iino, H, Wynter, C, Pillay, S, ...
a Department of Pathology, b Department of Surgery, University of Queensland, c Glaxo Conjoint Gastroenterology Laboratory, d Queensland Health Pathology Services, Royal Brisbane Hospital,...
Michael-Robinson, J, Biemer-Huttmann, A, Purdie, D, Walsh, M, Simms, L, Biden, K, ...
BACKGROUND—The presence of high level DNA microsatellite instability (MSI-H) in colorectal cancer is associated with an improved prognosis, as is the presence of tumour infiltrating lymphocytes...
A comparison of 13 guinea pig and human anti-tissue transglutaminase antibody ELISA kits
Wong, R C W, Wilson, R J, Steele, R H, Radford-Smith, G, Adelstein, S
Aims: Tissue transglutaminase (tTG) is a major autoantigen recognised by IgA anti-endomysial antibodies (IgA EMA). Enzyme linked immunosorbent assays (ELISA) for IgA anti-tissue transglutaminase...
Sandborn, W J, Feagan, B G, Radford-Smith, G, Kovacs, A, Enns, R, Innes, A, ...
Background: Targeting tumour necrosis factor α (TNF-α) has demonstrated efficacy in Crohn’s disease.
The Role of Cytokines in Inflammatory Bowel Disease
Radford-Smith, G., Jewell, D. P.
Cytokines play an important role in the development and persistence of the inflammatory lesions seen in Crohn's disease and ulcerative colitis. This review discusses the current thinking of the role...
TNFα and IL10 SNPs act together to predict disease behaviour in Crohn's disease
Fowler, E, Eri, R, Hume, G, Johnstone, S, Pandeya, N, Lincoln, D, ...
Background: The cytokines tumour necrosis factor (TNF)α and interleukin (IL)10 have been implicated in the pathogenesis of Crohn's disease (CD), with increased concentrations reported in patients...