Chase, A, La Starza, R, Beacci, D, Rosti, V, Galli, A, ...
We investigated genetically affected leukemic cells in FIP1L1-PDGFRA+ chronic eosinophilic leukemia (CEL) and in BCR-ABL1+ chronic myeloid leukemia (CML), two myeloproliferative disorders responsive...
Crescenzi, B., Chase, A., Starza, R.L., Beacci, D., Rosti, V., Galli, A., ...
We investigated genetically affected leukemic cells in FIP1L1-PDGFRA+ chronic eosinophilic leukemia (CEL) and in BCR-ABL1+ chronic myeloid leukemia (CML), two myeloproliferative disorders responsive...
Shakedown analysis for rolling and sliding contact problems (2006)
Ponter, A.R.S., Chen, Haofeng*, Ciavarella, M., Specchia, G.
There is a range of problems where repeated rolling or sliding contact occurs. For such problems shakedown and limit analyses provides significant advantages over other forms of analysis when a...
Shakedown analysis for rolling and sliding contact problems (2006)
Ponter, A.R.S., Chen, Haofeng, Ciavarella, M., Specchia, G.
There is a range of problems where repeated rolling or sliding contact occurs. For such problems shakedown and limit analyses provides significant advantages over other forms of analysis when a...
Shakedown analysis for rolling and sliding contact problems (2006)
Ponter, A.R.S., Chen, Haofeng, Ciavarella, M., Specchia, G.
There is a range of problems where repeated rolling or sliding contact occurs. For such problems shakedown and limit analyses provides significant advantages over other forms of analysis when a...
Shakedown analysis for rolling and sliding contact problems (2006)
Ponter, A.R.S., Chen, H., Ciavarella, M., Specchia, G.
There is a range of problems where repeated rolling and sliding contact occurs over a half space of an elastic–perfectly plastic material. For such problems shakedown and limit analysis provide...
Shakedown analysis for rolling and sliding contact problems (2006)
Ponter, A.R.S., Chen, H., Ciavarella, M., Specchia, G.
There is a range of problems where repeated rolling and sliding contact occurs over a half space of an elastic–perfectly plastic material. For such problems shakedown and limit analysis provide...
Cazzaniga, G, Alberti, F, Dell'Oro, M G, Gottardi, E, Specchia, G, ...
Mutations in exon 12 of the nucleophosmin (NPM1) gene occur in about 60% of adult AML with normal karyotype. By exploiting a specific feature of NPM1 mutants, that is insertion at residue 956 or...
Albano, F, Cambrin, G R, Quarta, G, Fabbiano, F, ...
Six patients with de novo acute myeloid leukemia (AML) and a t(2;3)(p15-21;q26-27) were identified among approximately 1000 cases enrolled in the GIMEMA trial. The t(2;3) was the sole anomaly in...
Martinelli, G., Iacobucci, I., Rosti, G., Pane, F., Amabile, M., Castagnetti, F., ...
Imatinib mesylate (STI571), a specific Bcr-Abl inhibitor, has shown a potent antileukemic activity in clinical studies of chronic myeloid leukemia (CML) patients. Early prediction of response to...
Martinelli, G., Iacobucci, I., Rosti, G., Pane, F., Amabile, M., Castagnetti, F., ...
Imatinib mesylate (STI571), a specific Bcr-Abl inhibitor, has shown a potent antileukemic activity in clinical studies of chronic myeloid leukemia (CML) patients. Early prediction of response to...
Martinelli, G., Iacobucci, I., Rosti, G., Pane, F., Amabile, M., Castagnetti, F., ...
Imatinib mesylate (STI571), a specific Bcr-Abl inhibitor, has shown a potent antileukemic activity in clinical studies of chronic myeloid leukemia (CML) patients. Early prediction of response to...
Aventin, A, Crescenzi, B, Gorello, P, Specchia, G, Cuneo, A, ...
Cimino, G, Izzo, B, Camera, A, Vitale, A, Quintarelli, C, ...
Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has a dismal prognosis. We prospectively evaluated minimal residual disease (MRD) by measuring BCR/ ABL levels with a...
Vegna, M L, Castoldi, G L, Spirito, F, Elia, L, ...
Within 285 adult acute lymphoblastic leukemias (ALL) included in the multicenter GIMEMA 0496 trial and prospectively studied by conventional cytogenetics, 18 cases (6%) with long arm deletion of...
Nanni, M, Sirleto, P, De Cuia, M R, Castoldi, G L, Cilloni, D, ...
INTRODUCTION: One hundred-and-six adult cases of acute lymphoblastic leukemia were prospectively investigated using a highly sensitive interphase fluorescence in situ hybridization assay which...
PREVTTALI, M., LANZARINI, L., MUSSINT, A., FERRARIO, M., ANGOLI, L., SPECCHIA, G.
A case of dobutamine-induced ST-segment elevation in a patient with angina at rest and severe two-vessel disease is described. Coronary angiography performed during the ischaemic episode showed...
POZZOLI, M., FEBO, O., TRAMARIN, R., PlNNA, G., COBELLI, F., SPECCHIA, G.
Haemodynamic studies suggest that the rapid deceleration of left ventricular inflow at the end of early diastole may play an important role in the genesis of the third heart sound (S3). To confirm...
ROVERE, M. T. LA, MORTARA, A., OPASICH, C., SPECCHIA, G.
The acute and chronic haemodynamic effects of nicardipine were studied, at rest and during exercise, in 10 post-myocardial infarction patients with latent cardiac failure and no signs of residual my...
Acute haemodynamic effects of diltiazem in patients with recent Q-wave myocardial infarction (1988)
GHIO, S., DE SERVI, S., FERRARIO, M., POMA, E., BRAMUCCI, E., ANGOLI, L., ...
The effects of diltiazem on left ventricular systolic and diastolic function were studied in 14 patients with a recent (12–20 days) Q-wave myocardial infarction. Left ventriculography with...
Opasich, C., Riccardi, G., Assandri, J., Calsamiglia, G., Forni, R., La Rovere, M., ...
To assess the clinical significance of monitoring during physical training in post-myocardial infarction (MI) patients with asymptomatic exercise-induced ischaemia, we studied 232 patients who were...
DE SERVI, S., BERZUINI, C., GHIO, S., FERRARIO, M., POMA, E., SCIRÈ, A., ...
The effect of surgical versus medical treatment on long-term prognosis in angina at rest was assessed using the Cox regression model for survival analysis in 400 patients complaining of recurrent...
Silent ischaemia in post-myocardial infarction patients submitted to physical training (1988)
Opasich, C., Cobelli, F., Farilla, C., Riccardi, G., Bosco, L., La Rovere, M. T., ...
Recently, more attention has been focused on the detection and treatment of silent myocardial ischaemia. Electrocardiographic signs of exercise-induced asymptomatic myocardial ischaemia are very...
Opasich, C., Cobelli, F., Riccardi, G., Rovere, M. T. LA, Calsamiglia, G., Specchia, G.
The anaerobic threshold (AT) has been proposed as an index to assess the functional status of patients with chronic heart failure. The focus of this report was to evaluate in post-myocardial...
Clinical significance of mitral regurgitation in patients with recent myocardial infarction (1988)
De Servi, S., Vaccari, L., Assandri, J., Poma, E., Cioffi, P., Sciré, A., ...
The prognostic implications of the presence of mitral regurgitation (MR) in patients with recent myocardial infarction has not been clarified yet. In March 1983, we undertook a prospective study in...
OPASICH, C., RICCARDI, G., FEBO, O., TRAMARIN, R., LEPORE, A. M., LUCA, C., ...
The resting and exertional haemodynamic effects of acute and chronic discontinuous (one tablet every 6 h) treatment with 5 mg of buccal nitroglycerin (BN) have been assessed in nine postinfarction...
OPASICH, C., FALCONE, C., COBELLI, F., ASSANDRI, J., LA ROVERE, M. T., RICCARDI, G., ...
In order to determine individual variability of ischaemic threshold on different days, 18 patients with exertional ischaemia at low workload were studied. All patients performed two exercise tests...
TRAMARIN, R., POZZOLI, M., FEBO, O., OPASICH, C., COLOMBO, E., COBELLI, F., ...
This study was designed to assess, by two-dimensional echocardiography, the effects of anticoagulant therapy on left ventricular thrombosis detected after acute myocardial infarction. Thirty-eight...
Clinical and aNgiographic Data in Early Post-Infarction Angina (1986)
De Servi, S., Vaccari, L., Graziano, G., Cornalba, C., Codega, S., Poma, E., ...
The preliminary results of a prospective study undertaken in patients with a first episode of acute myocardial infarction are presented. The clinical, electrocardiographic and angiographic...
DE SERVI, S., MUSSINI, A., ANGOLI, L., FERRARIO, M., BRAMUCCI, E., GAVAZZI, A., ...
To assess if cold-induced vasoconstriction may persist during exercise and contribute to the development myocardial ischaemia, we studied 11 patients with exertional angina and angiographically...
Management of Crescendo Angina (1985)
De Servi, S., Ghio, S., Ardissino, D., Collarini, L., Ferrario, M., Salerno, J., ...
The purpose of this study was to focus on the clinical and angiographical characteristics of patients with crescendo angina (i.e. worsening angina, including rest pain occurring against the...
ARDISSINO, D., SERVI, S. DE, SALERNO, J. A., SPECCHIA, G., PREVITALI, M., MUSSINI, A., ...
The duration of effect of single oral doses of 10 and 20 mg of nifedipine was studied in 10 patients with angiographically proven coronary crtery disease and with stable exercise-induced angina...
Multivessel coronary spasm as a cause of ischemic syncope in angina at rest (1982)
SALERNO, J. A., PREVITALI, M., TAVAZZI, L., CHIMIENTI, M., SERVI, S. DE, MEDICI, A., ...
Two patients with vasospastic angina at rest developed ST segment elevation both in the anterior and inferior leads during spontaneous and ergonovine-induced attacks. In both cases the acute...
De Servi, S., Mussini, A., Specchia, G., Bramucci, E., Gavazzi, A., Falcone, C., ...
Eight patients with coronary artery disease performed a cold pressor test (CPT) and hand-grip isometric exercise (HG) before and 20 min following sublingual administration of nifedipine. CPT...
De Servi, S, Specchia, G, Angoli, L
Chest pain induced by ergometrine was associated with ST depression and subsequent elevation in anterior leads in a 42-year-old man suffering from angina at rest. Coronary arteriography during the...
Marsico, F., Kubica, J., De Servi, S., Angoli, L., Bramucci, E., Costante, A. M., ...
OBJECTIVE--To relate the mechanism of luminal gain after directional atherectomy and balloon angioplasty to the morphological characteristics of the coronary lesions, assessed by intravascular...
Arbustini, E., Grasso, M., Fasani, R., Klersy, C., Diegoli, M., Porcu, E., ...
OBJECTIVE--To investigate the association of the three angiotensin converting enzyme (ACE) genotypes, DD, ID, and II, with the occurrence or absence of coronary atherosclerosis and with myocardial...
De Servi, S., Valentini, P., Angoli, L., Bramucci, E., Barberis, P., Mariani, G., ...
OBJECTIVE--To determine whether the increasing use of percutaneous transluminal angioplasty in patients with unstable angina has reduced the need for bypass surgery and whether this change in the...
Poli, A., Previtali, M., Lanzarini, L., Fetiveau, R., Diotallevi, P., Ferrario, M., ...
OBJECTIVE: To compare the ability of dobutamine and dipyridamole stress echocardiography to detect functional recovery of stunned but viable myocardial regions early after acute myocardial...
Ghio, S, Poli, A, Ferrario, M, Campana, C, Diotallevi, P, Eleuteri, E, ...
OBJECTIVE--To investigate whether the susceptibility to tolerance to glyceryl trinitrate is similar in different vascular beds in patients with chronic heart failure. PATIENTS--Twenty patients with...
De Servi, S, Ferrario, M, Ghio, S, Mussini, A, Angoli, L, Bramucci, E, ...
The effects of short term intravenous administration of gallopamil on coronary haemodynamic variables were studied in 10 patients with stable exertional angina and angiographically confirmed coronary...
Plaque erosion is a major substrate for coronary thrombosis in acute myocardial infarction
Arbustini, E, Dal, B, Morbini, P, Burke, A, Bocciarelli, M, Specchia, G, ...
OBJECTIVE—To evaluate the prevalence of plaque erosion as a substrate for coronary thrombosis. DESIGN—Pathological study in patients with acute myocardial infarction not treated with...
Enteroviral infection causing fatal myocarditis and subclinical myopathy
Arbustini, E, Porcu, E, Bellini, O, Grasso, M, Pilotto, A, Dal, B, ...
Enteroviral RNA detection in myocarditis and dilated cardiomyopathy is rare. Enteroviral particles and RNA have recently been identified in patient's skeletal muscle, suggesting that skeletal more...