Mitral regurgitation in patients with aortic stenosis undergoing valve replacement. (2009)
Unger, P, Dedobbeleer, C, Van Camp, G, Plein, D, Cosyns, B, Lancellotti, Patrizio
Service de Cardiologie CHU Sart Tilaman
Hilgert, Nele, Huentelman, Matthew, Thorburn, AQ, Fransen, Erik, Dieltjens, Nele, Meuller-Malesinska, M, ...
Hereditary hearing loss (HL) is a very heterogeneous trait, with 46 gene identifications for non-syndromic HL. Mutations in GJB2 cause up to half of all cases of severe-to-profound congenital...
Droogmans, S, Cosyns, B, Lahoutte, T, ...
In small animals studies, sick animals often have a significant reduction in heart rate while under anesthesia. The influence of heart rate reduction on Doppler myocardial imaging (DMI) parameters is...
Familial aggregation of tinnitus: a European multicentre study (2007)
Huyghe, J. R., Demeester, K., Topsakal, V., Van Eyken, E., Fransen, E., ...
Introduction and aim: Tinnitus is a common condition affecting approximately 20% of the older population. There is increasing evidence that changes in the central auditory system following cochlear...
KCNQ4: a gene for age-related hearing impairment? (2006)
Van Eyken, E, Van Laer, L, Fransen, E, Topsakal, V, Lemkens, N, Laureys, W, ...
Age-related hearing impairment (ARHI) is the most common sensory impairment among the elderly. It is a complex disorder influenced by genetic as well as environmental factors. SNPs in a candidate...
Ozzy, a Jag1 vestibular mouse mutant, displays characteristics of Alagille syndrome (2006)
Vrijens, Karen, Thys, Sofie, De Jeu, Marcel T, Postnov, Andrei A, Pfister, Markus, Cox, Luk; U0042467, ...
The mouse mutant Ozzy, originating from an ENU-mutagenesis programme, displays a head bobbing phenotype. We report here that Ozzy mice show a clear deficit in vestibulo-ocular reflex (VOR). Micro-CT...
438 Valvular heart disease associated with ecstasy abuse (2006)
Droogmans, S., Cosyns, B., Kemdem, A., Close, L., Franken, P.R., D'haenen, H., ...
Mice lacking Dfna5 show a diverging number of cochlear fourth row outer hair cells (2005)
Van Laer, Lut, Pfister, Markus, Thys, Sofie, Vrijens, Karen, Mueller, Marcus, Umans, Lieve, ...
A complex mutation in DFNA5, resulting in exon 8 skipping, causes autosomal dominant hearing impairment, which starts in the high frequencies between 5 and 15 years of age and progressively affects...
Del Castillo, F J, Rodríguez-Ballesteros, M, Alvarez, A, Hutchin, T, Leonardi, E, De Oliveira, C A, ...
Global and regional parameters of dyssynchrony in ischemic and nonischemic cardiomyopathy (2005)
Van De Veire, Nico, De Sutter, Johan, VAN CAMP, G, VANDERVOORT, P, LANCELLOTTI, P, COSYNS, B, ...
De Sutter, Johan, Van De Veire, Nico, VAN CAMP, G, LANCELLOTTI, P, VANDERVOORT, P, MUYLDERMANS, L, ...
270 How interpret exercise induced changes in E/Ea in patients with systolic heart failure (2005)
Lancellotti, P, Defrance, A., Lempereur, M., Cosyns, B., Van Camp, G., Pierard, L.A.
598 Normal values and reproducibility of Doppler myocardial imaging in adult male rats (2005)
Weytjens, C., Cosijns, B., Gallez, C., Lahoute, T., D'hooge, J., Van Camp, G.
Cosyns, B, El Haddad, P, Lignian, H, Daniels, C, Weytjens, C, Schoors, D, ...
Aims: The study examined the value of contrast echocardiography (CE) in the assessment of left ventricular (LV) wall motion in ventilated patients in comparison with transesophageal (TOE) and...
Huygen, Patrick L M, Fransen, Erik, Van Camp, G, ...
OBJECTIVE: To evaluate audiometric and vestibular signs and symptoms in a new DFNA9 family. SETTING: Tertiary referral centers. METHODS: A multigeneration Belgian family with late-onset progressive...
Native Valve Endocarditis with Aorta-to-Left Atrial Fistula Due to Corynebacterium amycolatum (2003)
Daniëls, C, Schoors, D, Van Camp, G
Infective endocarditis remains a pathology with a high rate of complications and mortality. One of the most dramatic complications is abscess formation. A rare evolution of abscess formation is the...
Cosyns, B., Menassel, M., Mantia, M., Schoors, D., ...
DFNA10/EYA4 - the clinical picture. (2002)
DE LEENHEER, EM, HUYGEN, PL, WAYNE, S, VERSTREKEN, M, DECLAU, F, VAN CAMP, G, ...
Clinical features of DFNA5. (2002)
De Leenheer, Els, VAN ZUYLEN, DA, VAN LAER, L, VAN CAMP, G, HUYGEN, PL, HUIZING, EH, ...
DFNA2/KCNQ4 and its manifestations. (2002)
De Leenheer, Els, ENSINK, RJ, KUNST, HP, MARRES, HA, TALEBIZADEH, Z, DECLAU, F, ...
Further delineation of the DFNA5 phenotype: Results of speech recognition tests. (2002)
De Leenheer, Els, VAN ZUIJLEN, DA, VAN LAER, L, VAN CAMP, G, HUYGEN, P, HUIZING, EH, ...
Longitudinal and cross-sectional phenotype analysis in a new, large dutch DFNA2/KCNQ4 family. (2002)
DE LEENHEER, EMR, HUYGEN, P, Coucke, Paul, ADMIRAAL, R, VAN CAMP, G, CREMERS, C
Van Camp, G., Franken, P.R., Schoors, D., Hagers, Y., Koole, M., Demoor, D., ...
Aims: To evaluate the impact of second harmonic (SH) imaging compared to fundamental mode (FM) on the echocardiographic determination of ejection fraction (EF) and wall motion score index (WMSI),...
Van Camp, G, De Mey, J, Daenen, Willem; U0018285, Budts, Werner; U0037749, Schoors, D
Pulmonic stenosis and stenosis of the right ventricular outflow tract related to extrinsic compression have been described in patients with tumors, in a patient with a pericardial cyst, and in...
VAN CAMP, G, CARLIER, S, COSYNS, B, PLEIN, D, MENASSEL, M, JOSSE, T, ...
L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns (1998)
Two frequent missense mutations in Pendred syndrome (1998)
Van Hauwe, P, Everett, LA, Coucke, P, Scott, DA, Kraft, ML, Ris-Stalpers, C, ...
L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns (1998)
Fransen, E, D'Hooge, R, Van Camp, G, Verhoye, M, Sijbers, J, Reyniers, E, ...
Localization of a gene for otosclerosis to chromosome 15q25-q26 (1998)
Tomek, MS, Brown, MR, Mani, SR, Ramesh, A, Srisailapathy, CR, Coucke, P, ...
An autosomal recessive nonsyndromic form of sensorineural hearing loss maps to 3p-DFNB6 (1995)
Fukushima, K, Ramesh, A, Srisailapathy, CR, Ni, L, Wayne, S, O'Neill, ME, ...
Van Hul, W., Backhovens, H., Van Camp, G., STINISSEN, Piet, Cruts, M., Wehnert, A., ...
We were able to refine the chromosomal position of two existing marker loci, using an extended chromosome 21 somatic cell hybrid panel. The locus D21S26 mapped in the region 21q11.2–q21.1, and the...
Construction of a physical map of chromosome 21q in relation to Alzheimer's disease (1991)
STINISSEN, Piet, Van Hul, W., Van Camp, G., Backhovens, H., Wehnert, A., Vandenberghe, A., ...
Van Hul, W., Backhovens, H., Van Camp, G., STINISSEN, Piet, Cruts, M., Wehnert, A., ...
We were able to refine the chromosomal position of two existing marker loci, using an extended chromosome 21 somatic cell hybrid panel. The locus D21S26 mapped in the region 21q11.2–q21.1, and the...
Van Camp, G., Backhovens, H., Cruts, M., Wehnert, A., Van Hul, W., STINISSEN, Piet, ...
Linkage studies in families with presenile onset of Alzheimer's disease (AD) indicated the presence of a predisposing gene on the proximal long arm of chromosome 21. We mapped four new loci in the...
Construction of a physical map of chromosome 21q in relation to Alzheimer's disease (1991)
STINISSEN, Piet, Van Hul, W., Van Camp, G., Backhovens, H., Wehnert, A., Vandenberghe, A., ...
Molecular genetics of familial Alzheimer's disease (1990)
STINISSEN, Piet, MARTIN, Jan, Van Broeckhoven, C., Backhovens, H., Van Camp, G., Van Hul, W., ...
Molecular genetics of familial Alzheimer's disease (1990)
STINISSEN, Piet, MARTIN, Jan, Van Broeckhoven, C., Backhovens, H., Van Camp, G., Van Hul, W., ...
Eyers, M, Chapelle, S, Van Camp, G, Goossens, H, De Wachter, R
By comparing nucleic acid sequences determined for one of the most variable areas of 23S rRNA genes of 23 Campylobacter strains, we were able to identify regions specific for thermophilic...
A polymorphic locus [D21S144] is detected by probe pVC12 on chromosome 21.
Van Camp, G, Stinissen, P, Vandenberghe, A, Van Broeckhoven, C
A novel locus for autosomal dominant nonsyndromic hearing loss, DFNA13, maps to chromosome 6p.
Brown, M R, Tomek, M S, Van Laer, L, Smith, S, Kenyon, J B, Van Camp, G, ...
Nonsyndromic hearing loss (NSHL) is the most common type of hearing impairment in the elderly. Environmental and hereditary factors play an etiologic role, although the relative contribution of each...
Van Buchem disease (hyperostosis corticalis generalisata) maps to chromosome 17q12-q21.
Van Hul, W, Balemans, W, Van Hul, E, Dikkers, F G, Obee, H, Stokroos, R J, ...
Van Buchem disease (hyperostosis corticalis generalisata; OMIM 239100 [http://www3.ncbi.nlm.nih. gov:80/htbin-post/Omim/dispmim?239100]) is an autosomal recessive disorder characterized by...
Fukushima, K, Kasai, N, Ueki, Y, Nishizaki, K, Sugata, K, Hirakawa, S, ...
The sixteenth gene to cause autosomal dominant nonsyndromic hearing loss (ADNSHL), DFNA16, maps to chromosome 2q23-24.3 and is tightly linked to markers in the D2S2380-D2S335 interval. DFNA16 is...
Eyers, M, Chapelle, S, Van Camp, G, Goossens, H, De Wachter, R
By comparing nucleic acid sequences determined for one of the most variable areas of 23S rRNA genes of 23 Campylobacter strains, we were able to identify regions specific for thermophilic...
A polymorphic locus [D21S144] is detected by probe pVC12 on chromosome 21.
Van Camp, G, Stinissen, P, Vandenberghe, A, Van Broeckhoven, C
Van Buchem disease (hyperostosis corticalis generalisata) maps to chromosome 17q12-q21.
Van Hul, W, Balemans, W, Van Hul, E, Dikkers, F G, Obee, H, Stokroos, R J, ...
Van Buchem disease (hyperostosis corticalis generalisata; OMIM 239100 [http://www3.ncbi.nlm.nih. gov:80/htbin-post/Omim/dispmim?239100]) is an autosomal recessive disorder characterized by...
Fukushima, K, Kasai, N, Ueki, Y, Nishizaki, K, Sugata, K, Hirakawa, S, ...
The sixteenth gene to cause autosomal dominant nonsyndromic hearing loss (ADNSHL), DFNA16, maps to chromosome 2q23-24.3 and is tightly linked to markers in the D2S2380-D2S335 interval. DFNA16 is...
A gene for autosomal dominant nonsyndromic hearing loss (DFNA12) maps to chromosome 11q22-24.
Verhoeven, K, Van Camp, G, Govaerts, P J, Balemans, W, Schatteman, I, Verstreken, M, ...
We performed linkage analysis in a Belgian family with autosomal dominant midfrequency hearing loss, which has a prelingual onset and a nonprogressive course in most patients. We found LOD scores >6...
A novel locus for autosomal dominant nonsyndromic hearing loss, DFNA13, maps to chromosome 6p.
Brown, M R, Tomek, M S, Van Laer, L, Smith, S, Kenyon, J B, Van Camp, G, ...
Nonsyndromic hearing loss (NSHL) is the most common type of hearing impairment in the elderly. Environmental and hereditary factors play an etiologic role, although the relative contribution of each...
Recognition of pacemaker lead infection by transoesophageal echocardiography
Van Camp, G, Vandenbossche, J L
Transoesophageal echocardiography identified a pacemaker lead infection in a patient in whom transthoracic echocardiography was negative and there were no specific signs of skin inflammation over the...
Van Camp, G, Liebens, I, Silance, P G, Cham, B, Vandenbossche, J L
A 72 year old man was admitted with severe dyspnoea. Ten days before he had had intense thoracic pain with loss of consciousness that was followed by increased dyspnoea. A continuous murmur was heard...
Van Camp, G, Cosyns, B, Vandenbossche, J L
OBJECTIVE--To elucidate why different types of contrast appear in the left atrium during transoesophageal echocardiographic contrast studies. This should lead to a more uniform definition of true...
Van Camp, G, Van Thienen, M N, Handig, I, Van Roy, B, Rao, V S, Milunsky, A, ...
Waardenburg syndrome (WS) is an autosomal dominant disorder characterised by pigmentary abnormalities and sensorineural deafness. It is subcategorised into type 1 (WS1) and type 2 (WS2) on the basis...
Lench, N J, Markham, A F, Mueller, R F, Kelsell, D P, Smith, R J, Willems, P J, ...
We report a mutation in the connexin 26 gene (Cx26) in a consanguineous Moroccan family linked to the DFNA3/DFNB1 locus on human chromosome 13q11-q12. Affected subjects display congenital, bilateral,...
Genotype-phenotype correlation in L1 associated diseases.
Fransen, E, Van Camp, G, D'Hooge, R, Vits, L, Willems, P J
The neural cell adhesion molecule L1 (L1CAM) plays a key role during embryonic development of the nervous system and is involved in memory and learning. Mutations in the L1 gene are responsible for...
Identification of two different mutations in the PDS gene in an inbred family with Pendred syndrome
Coucke, P, Van Hauwe, P, Everett, L, Demirhan, O, Kabakkaya, Y, Dietrich, N, ...
Recently the gene responsible for Pendred syndrome (PDS) was isolated and several mutations in the PDS gene have been identified in Pendred patients. Here we report the occurrence of two different...
Van Camp, G., Kunst, H., Flothmann, K., McGuirt, W., Wauters, J., Marres, H., ...
Non-syndromic hearing impairment is one of the most heterogeneous hereditary conditions, with more than 40 reported gene localisations. We have identified a large Dutch family with autosomal...
A common founder for the 35delG GJB2 gene mutation in connexin 26 hearing impairment
Van Laer, L, Coucke, P, Mueller, R, Caethoven, G, Flothmann, K, Prasad, S, ...
Fifty to eighty percent of autosomal recessive congenital severe to profound hearing impairment result from mutations in a single gene, GJB2, that encodes the protein connexin 26. One mutation of...
Linkage of otosclerosis to a third locus (OTSC3) on human chromosome 6p21.3-22.3
Chen, W, Campbell, C, Green, G, Komodikis, C, Manolidis, L, ...
Clinical otosclerosis (OMIM 166800/605727) has a prevalence of 0.2-1% among white adults, making it the single most common cause of hearing impairment in this group. It is caused by abnormal bone...
A genotype-phenotype correlation for GJB2 (connexin 26) deafness
Cryns, K, Orzan, E, Murgia, A, Huygen, P, Moreno, F, Del Castillo, I, ...
Introduction: Mutations in GJB2 are the most common cause of non-syndromic autosomal recessive hearing impairment, ranging from mild to profound. Mutation analysis of this gene is widely available as...
DFNA5: hearing impairment exon instead of hearing impairment gene?
Van Laer, L, Vrijens, K, Thys, S, Smith, R, Van Bockstaele, D R, ...
Methods: We performed transfection experiments in mammalian cell lines (HEK293T and COS-1) with green fluorescent protein (GFP) tagged wildtype and mutant DFNA5 and analysed cell death with flow...
A fifth locus for otosclerosis, OTSC5, maps to chromosome 3q22–24
Chen, W, Lee, Y, Nurnberg, P, Pennings, R, ...
A novel locus for autosomal dominant non-syndromic hearing loss, DFNA31, maps to chromosome 6p21.3
Snoeckx, R, Kremer, H, Ensink, R, Flothmann, K, De Brouwer, A, Smith, R, ...
Objective:To investigate the genes involved in a Dutch family with NSSHL.
Superior vena cava syndrome associated with Nocardia farcinica infection
Abdelkafi, S., Dubail, D., Bosschaerts, T., Brunet, A., Van Camp, G., De Marneffe, M., ...
A case is described of severe Nocardia farcinica infection which mimicked a pulmonary neoplasm with pneumonia, superior vena cava syndrome, pericarditis, and hypertrophic osteoarthropathy. Treatment...
Del Castillo, F J, Rodriguez-Ballest..., M, Alvarez, A, Hutchin, T, Leonardi, E, De Oliveira, C A, ...
Mutation of COL11A2 causes autosomal recessive non-syndromic hearing loss at the DFNB53 locus
Chen, W, Kahrizi, K, Meyer, N, Riazalhosseini, Y, Van Camp, G, Najmabadi, H, ...
Background: Allele variants of COL11A2, encoding collagen type XI α2, cause autosomal dominant non-syndromic hearing loss (ARNSHL) at the DFNA13 locus (MIM 601868) and various syndromes that include...