Rose, R.J., Verger, D., Daviter, T., Remaut, H., Paci, E., Waksman, G., ...
P pili are multisubunit fibers essential for the attachment of uropathogenic Escherichia coli to the kidney. These fibers are formed by the noncovalent assembly of six different homologous subunit...
Paci, E., Rose, R.J., Welsh, T.S., Waksman, G., Ashcroft, A.E., Radford, S.E.
Adhesive multi-subunit fibres are assembled on the surface of many pathogenic bacteria via the chaperone-usher pathway. In the periplasm, a chaperone donates a β-strand to a pilus subunit to...
Meng, G., Surana, N.K., Waksman, G.
Autotransporter proteins are defined by the ability to drive their own secretion across the bacterial outer membrane. The Hia autotransporter of Haemophilus influenzae belongs to the trimeric...
Rothwell, P.J., Mitaksov, M., Waksman, G.
Various kinetic studies on nucleotide incorporation by DNA polymerases have established that a rate-limiting step occurs that is crucial in the mechanism of discrimination between correct versus...
Structural basis for host recognition by the Haemophilus influenzae Hia autotransporter. (2004)
Yeo, HJ, Cotter, SE, Laarmann, S, Juehne, T, StGeme, JW, Waksman, G
The Anticoagulant Thrombin Mutant W215A/E217A Has a Collapsed Primary Specificity Pocket. (2004)
Pineda, A, Chen, Z, Caccia, S, Cantwell, A, Savvides, S, Waksman, G, ...
Venkataraman, G, Sasisekharan, V, Herr, A B, Ornitz, D M, Waksman, G, Cooney, C L, ...
Central to signaling by fibroblast growth factors (FGFs) is the oligomeric interaction of the growth factor and its high-affinity cell surface receptor, which is mediated by heparin-like...
Korolev, S, Nayal, M, Barnes, W M, Di Cera, E, Waksman, G
The crystal structure of the large fragment of the Thermus aquaticus DNA polymerase (Klentaq1), determined at 2.5-A resolution, demonstrates a compact two-domain architecture. The C-terminal domain...
Common amino acid domain among endopolygalacturonases of ascomycete fungi.
The endopolygalacturonase (EC 3.2.1.15) enzymes produced in vitro by three ascomycete fungi, Aspergillus niger, Sclerotinia sclerotiorum, and Colletotrichum lindemuthianum were studied by using...
Waksman, G, Hamel, E, Fournié-Zaluski, M C, Roques, B P
The neutral endopeptidase EC 3.4.24.11, also designated enkephalinase, has been visualized by in vitro autoradiography using the tritiated inhibitor...
Lemay, G, Zollinger, M, Waksman, G, Roques, B P, Crine, P, Boileau, G
Neutral endopeptidase-24.11 (EC 3.4.24.11) (NEP) is a transmembrane metallo-endopeptidase that has been shown to be involved in the degradation of several mammalian neuropeptides, including...
Kinetic studies of the polygalacturonase enzyme from Colletotrichum lindemuthianum.
Waksman, G, Turner, G, Walmsley, A R
The intrinsic protein fluorescence of the polygalacturonase from Colletotrichium lindemuthianum was exploited in stopped-flow experiments aimed at elucidating the kinetic mechanism for this enzyme....
Waksman, G, Hamel, E, Delay-Goyet, P, Roques, B P
The cellular localization of rat brain enkephalinase was studied after induction of selective unilateral lesions using in vitro quantitative autoradiography of the specific binding of the enzyme...
The crystal structures of two ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I (Klentaq1) with a primer/template DNA and dideoxycytidine triphosphate, and that of a...
Venkataraman, G, Sasisekharan, V, Herr, A B, Ornitz, D M, Waksman, G, Cooney, C L, ...
Central to signaling by fibroblast growth factors (FGFs) is the oligomeric interaction of the growth factor and its high-affinity cell surface receptor, which is mediated by heparin-like...
Korolev, S, Nayal, M, Barnes, W M, Di Cera, E, Waksman, G
The crystal structure of the large fragment of the Thermus aquaticus DNA polymerase (Klentaq1), determined at 2.5-A resolution, demonstrates a compact two-domain architecture. The C-terminal domain...
Common amino acid domain among endopolygalacturonases of ascomycete fungi.
The endopolygalacturonase (EC 3.2.1.15) enzymes produced in vitro by three ascomycete fungi, Aspergillus niger, Sclerotinia sclerotiorum, and Colletotrichum lindemuthianum were studied by using...
Waksman, G, Hamel, E, Fournié-Zaluski, M C, Roques, B P
The neutral endopeptidase EC 3.4.24.11, also designated enkephalinase, has been visualized by in vitro autoradiography using the tritiated inhibitor...
Lemay, G, Zollinger, M, Waksman, G, Roques, B P, Crine, P, Boileau, G
Neutral endopeptidase-24.11 (EC 3.4.24.11) (NEP) is a transmembrane metallo-endopeptidase that has been shown to be involved in the degradation of several mammalian neuropeptides, including...
Kinetic studies of the polygalacturonase enzyme from Colletotrichum lindemuthianum.
Waksman, G, Turner, G, Walmsley, A R
The intrinsic protein fluorescence of the polygalacturonase from Colletotrichium lindemuthianum was exploited in stopped-flow experiments aimed at elucidating the kinetic mechanism for this enzyme....
Waksman, G, Hamel, E, Delay-Goyet, P, Roques, B P
The cellular localization of rat brain enkephalinase was studied after induction of selective unilateral lesions using in vitro quantitative autoradiography of the specific binding of the enzyme...
The crystal structures of two ternary complexes of the large fragment of Thermus aquaticus DNA polymerase I (Klentaq1) with a primer/template DNA and dideoxycytidine triphosphate, and that of a...
Réty, S., Fütterer, K., Grucza, R. A., Munoz, C. M., Frazier, W. A., Waksman, G.
The Src homologous and collagen-like (SHC) protein plays an essential role in signal transduction pathways in that it participates in the chain of events that leads to the activation of the protein...
Korolev, S., Yao, N., Lohman, T. M., Weber, P. C., Waksman, G.
Three helicase structures have been determined recently: that of the DNA helicase PcrA, that of the hepatitis C virus RNA helicase, and that of the Escherichia coli DNA helicase Rep. PcrA and Rep...
Li, Y., Kong, Y., Korolev, S., Waksman, G.
The crystal structures of the Klenow fragment of the Thermus aquaticus DNA polymerase I (Klentaq1) complexed with four deoxyribonucleoside triphosphates (dNTP) have been determined to 2.5 A...