Cation Involvement in Telomestatin Binding to G-Quadruplex DNA (2010)
Rosu, Frédéric, Gabelica, Valérie, Smargiasso, Nicolas, Mazzucchelli, Gabriel, Shin-ya, Kazuo, De Pauw, Edwin
The binding mode of telomestatin to G-quadruplex DNA has been investigated using electrospray mass spectrometry, by detecting the intact complexes formed in ammonium acetate. The mass measurements...
Turtoi, Andrei, Mazzucchelli, Gabriel, De Pauw, Edwin
Protein quantification based upon mass spectrometry is gaining ground in diverse applications of biological and clinical relevance. The present article focuses on one of the most complex biological...
Piette, Florence, D'Amico, Salvino, Struvay, Caroline, Mazzucchelli, Gabriel, Renaut, J, Tutino, ML, ...
Cation Involvement in Telomestatin Binding to G-Quadruplex DNA (2010)
Frédéric Rosu, Valérie Gabelica, Nicolas Smargiasso, Gabriel Mazzucchelli, Kazuo Shin-Ya, Edwin De Pauw
The binding mode of telomestatin to G-quadruplex DNA has been investigated using electrospray mass spectrometry, by detecting the intact complexes formed in ammonium acetate. The mass measurements...
Cation Involvement in Telomestatin Binding to G-Quadruplex DNA (2010)
Frédéric Rosu, Valérie Gabelica, Nicolas Smargiasso, Gabriel Mazzucchelli, Kazuo Shin-Ya, Edwin De Pauw
The binding mode of telomestatin to G-quadruplex DNA has been investigated using electrospray mass spectrometry, by detecting the intact complexes formed in ammonium acetate. The mass measurements...
Turtoi, Andrei, Mazzucchelli, Gabriel, Dobson, Rowan, De Pauw, Edwin
57th American Society for Mass Spectrometry (ASMS) Conference
Frederich, Michel, Delvaux, David, Gangolf, Marjorie, Dive, Georges, Mazzucchelli, Gabriel, Elias, Benjamin, ...
Thiamine and its three phosphorylated derivatives (mono-, di- and triphosphate) occur naturally in most cells. Recently, we reported the presence of a fourth thiamine derivative, adenosine thiamine...
Mercury immune toxicity in harbour seals: links to in vitrotoxicity (2008)
Das, Krishna, Siebert, Ursula, Gillet, Audrey, Dupont, Aurélie, Di-Poï, Carole, Fonfara, Sonja, ...
Abstract Background Mercury is known to bioaccumulate and to magnify in marine mammals, which is a cause of great concern in terms of their general health. In particular, the immune system is known...
Proteome alteration induced by hTERT transfection of human fibroblast cells (2008)
Mazzucchelli, Gabriel, Gabelica, Valérie, Smargiasso, Nicolas, Fleron, Maximilien, Ashimwe, Wilson, Rosu, Frédéric, ...
Background: Telomerase confers cellular immortality by elongating telomeres, thereby circumventing the Hayflick limit. Extended-life-span cells have been generated by transfection with the human...
Mercury immune toxicity in harbour seals: Links to in vitro toxicity (2008)
Das, Krishna, Siebert, Ursula, Gillet, Audrey, Dupont, Aurélie, Di-Poï, Carole, Fonfara, Sonja, ...
Background Mercury is known to bioaccumulate and to magnify in marine mammals, which is a cause of great concern in terms of their general health. In particular, the immune system is known to be...
Mazzucchelli, Gabriel, Cellier, Nicolas, Mshviladzade, Vakhtang, Elias, Riad, Shim, Yong-Ho, Touboul, David, ...
The viability, cytolysis and apoptosis-mediated cellular death induced by giganteosides D and E (Gig-D and Gig-E) and hederacolchisides A and A1 (Hcol-A and Hcol-A1) were analyzed in HL-60 cells....
Mazzucchelli, Gabriel, Cellier, Nicolas A, Mshviladzade, Vakhtang, Elias, Riad, Shim, Yong-Ho, Touboul, David, ...
Hederacolchiside A1 was used to progressively permeabilize the membrane of human melanoma MEL-5 cells. Holes formation was followed by Scanning Electron Microscopy and interaction of the saponin with...
Identification of aphid salivary proteins: a proteomic investigation of Myzus persicae. (2008)
Harmel, Nicolas, Letocart, E, Cherqui, A, Giordanengo, P, Mazzucchelli, Gabriel, Guillonneau, F, ...
The role of insect saliva in the first contact between an insect and a plant is crucial during feeding. Some elicitors, particularly in insect regurgitants, have been identified as inducing plant...
Contribution of glycoproteomics in the search for accessible biomarkers in human lymphoma (2008)
Kischel, Philippe, Greffe, Yannick, Waltregny, David, Chrétien, N, Mazzucchelli, Gabriel, De Pauw, Edwin, ...
FNRS Contact Group Proteomics (GCProt) 4th annual meeting: Chromatin Modifications and Protein Glycosylation
Proteomic analysis of telomerase inhibition by telomere specific ligands (2008)
Mazzucchelli, Gabriel, Gabelica, Valérie, Smargiasso, Nicolas, Rosu, Frédéric, Gillet, Marie-Claire, Riou, Jean-François, ...
8th International Conference of Anticancer Research
Discovery of a natural thiamine adenine nucleotide (2007)
Bettendorff, Lucien, Wirtzfeld, Barbara, Makarchikov, Alexander F, Mazzucchelli, Gabriel, Frederich, Michel, Gigliobianco, Tiziana, ...
Several important cofactors are adenine nucleotides with a vitamin as the catalytic moiety. Here, we report the discovery of the first adenine nucleotide containing vitamin B1: adenosine thiamine...
PROTEOMIC ANALYSIS OF WILD TYPE AND LUCIFERASE REPORTER HEPG2 CELLS EXPOSED TO TCDD (2007)
Lambert, Damien, Mazzucchelli, Gabriel, De Pauw, Edwin, Maghuin-Rogister, Guy, Muller, Marc, Scippo, Marie-Louise
International Symposium on halogenated persistent organic polluatants - DIOXIN 2007
Proteomics in Myzus persicae: effect of aphid host plant switch. (2006)
Francis, Frédéric, Gerkens, Pascal, Harmel, Nicolas, Mazzucchelli, Gabriel, De Pauw, Edwin, Haubruge, Eric
Chemical ecology is the study of how particular chemicals are involved in interactions of organisms with each other and with their surroundings. In order to reduce insect attack, plants have evolved...
Modulation of intestinal urea cycle by dietary spermine in suckling rat (2005)
Gharbi, Myriam, Powroznik, B, Mazzucchelli, Gabriel, Deville, Christelle, Nollevaux, G, Rusu, D, ...
Argininosuccinate synthetase, an ubiquitous enzyme in mammals, catalyses the formation of argininosuccinate, the precursor of arginine. Arginine is recognised as an essential amino acid in foetuses...
Brenez, C, Gerkens, P, Mazzucchelli, Gabriel, Jauniaux, Thierry, Eppe, Gauthier, De Pauw, Edwin, ...
The cell lines chosen have demonstrated a positive response in terms of cell proliferation and associated modifications in proteins content, evaluated through DNA and proteins synthesis, at...