Urbani, Simona, Boni, Carolina, Missale, Gabriele, Elia, Gianfranco, Cavallo, Cristina, Massari, Marco, ...
Hepatitis B and hepatitis C viruses (HBV and HCV) are both noncytopathic and can cause acute and chronic infections of the liver. Although they share tropism for the same organ, development of...
Urbani, Simona, Boni, Carolina, Missale, Gabriele, Elia, Gianfranco, Cavallo, Cristina, Massari, Marco, ...
Hepatitis B and hepatitis C viruses (HBV and HCV) are both noncytopathic and can cause acute and chronic infections of the liver. Although they share tropism for the same organ, development of...
Urbani, Simona, Amadei, Barbara, Tola, Daniela, Massari, Marco, Schivazappa, Simona, Missale, Gabriele, ...
Hepatitis C virus (HCV)-specific CD8 cell exhaustion may represent a mechanism of HCV persistence. The inhibitory receptor PD-1 has been reported to be up-regulated in exhausted CD8 cells. Therefore,...
Characterization of Hepatitis B Virus (HBV)-Specific T-Cell Dysfunction in Chronic HBV Infection▿
Boni, Carolina, Fisicaro, Paola, Valdatta, Caterina, Amadei, Barbara, Di Vincenzo, Paola, Giuberti, Tiziana, ...
Dysfunctional CD8+ T cells present in chronic virus infections can express programmed death 1 (PD-1) molecules, and the inhibition of the engagement of PD-1 with its ligand (PD-L1) has been reported...
Heterologous T cell immunity in severe hepatitis C virus infection
Urbani, Simona, Amadei, Barbara, Fisicaro, Paola, Pilli, Massimo, Missale, Gabriele, Bertoletti, Antonio, ...
Hepatitis C virus (HCV) can cause liver disease of variable severity. Expansion of preexisting memory CD8 T cells by cross-reactivity with a new heterologous virus infection has been shown in mice to...