Gad Galili

Publication List Details

Period

1981 - 2009

Number

48

Co-Authors

Coordinations between gene modules control the operation of plant amino acid metabolic networks (2009)

Less, Hadar, Galili, Gad

Abstract Background Being sessile organisms, plants should adjust their metabolism to dynamic changes in their environment. Such adjustments need particular coordination in branched metabolic...

Characterization of monofunctional aspartate kinase genes in maize and their relationship with free amino acid content in the endosperm (2007)

Wang, Xuelu, Lopez-Valenzuela, Jose A., Gibbon, Bryan C., Gakiere, Bertrand, Galili, Gad, Larkins, Brian A.

A quantitative trait locus has previously been identified in maize (Zea mays L.) that influences the level of free amino acids in the endosperm, especially those from the aspartate pathway: lysine,...

The autophagy-associated Atg8 gene family operates both under favourable growth conditions and under starvation stresses in Arabidopsis plants (2005)

Sláviková, Silvia, Shy, Galia, Yao, Youli, Glozman, Rina, Levanony, Hanna, Pietrokovski, Shmuel, ...

Arabidopsis plants possess a family of nine AtAtg8 gene homologues of the yeast autophagy-associated Apg8/Aut7 gene. To gain insight into how these genes function in plants, first, the expression...

The autophagy-associated Atg8 gene family operates both under favourable growth conditions and under starvation stresses in Arabidopsis plants (2005)

Sláviková, Silvia, Shy, Galia, Yao, Youli, Glozman, Rina, Levanony, Hanna, Pietrokovski, Shmuel, ...

Arabidopsis plants possess a family of nine AtAtg8 gene homologues of the yeast autophagy-associated Apg8/Aut7 gene. To gain insight into how these genes function in plants, first, the expression...

The autophagy-associated Atg8 gene family operates both under favourable growth conditions and under starvation stresses in Arabidopsis plants (2005)

Sláviková, Silvia, Shy, Galia, Yao, Youli, Glozman, Rina, Levanony, Hanna, Pietrokovski, Shmuel, ...

Arabidopsis plants possess a family of nine AtAtg8 gene homologues of the yeast autophagy-associated Apg8/Aut7 gene. To gain insight into how these genes function in plants, first, the expression...

Cloning and characterization of Arabidopsis homologues of the animal CstF complex that regulates 3' mRNA cleavage and polyadenylation (2002)

Yao, Youli, Song, Luhua, Katz, Yael, Galili, Gad

The 3′ cleavage and polyadenylation of mRNAs has been studied in detail in animals and yeast, but not in plants. Aimed at elucidating the regulation of mRNA 3′ end formation in plants, three...

Expression patterns of genes encoding endomembrane proteins support a reduced function of the Golgi in wheat endosperm during the onset of storage protein deposition (2001)

Shy, Galia, Ehler, Linda, Herman, Eliot, Galili, Gad

Wheat storage proteins are deposited in the vacuole of maturing endosperm cells by a novel pathway that is the result of protein body formation by the endoplasmic reticulum followed by autophagy into...

Synthetic oligonucleotide tails inhibit in vitro and in vivo translation of SP6 transcripts of maize zein cDNA clones (1986)

Galili, Gad, Kawata, Evelynn E., Cuellar, Richard E., Smith, L.D., Larkins, Brian A.

A maize zein cDNA clone was used to synthesize mRNA with the SP6 in vitro transcription system. Although we obtained full-length transcripts of the cDNA sequence, these were inefficient templates for...

Changes in chromatin structure at the replication fork. II The DNPs containing nascent DNA and a transient chromatin modification detected by DNAase I (1981)

Galili, Gad, Levy, Abraham, Jakob, Karl M.

Discrete deoxyribonucleoproteins (DNPs) containing nascent and/or bulk DNA, were obtained by fractionating micrococcal nuclease digests of nuclei from 3H-thymidine pulse (15–20 sec) and...

Expression of an Arabidopsis Aspartate Kinase/Homoserine Dehydrogenase Gene Is Metabolically Regulated by Photosynthesis-Related Signals but Not by Nitrogenous Compounds1

Zhu-Shimoni, Judith X., Galili, Gad

Although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids. In this...

Purification and Characterization of Bifunctional Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase from Developing Soybean Seeds1

Miron, Daphna, Ben-Yaacov, Sari, Reches, Dalit, Schupper, Avigail, Galili, Gad

Both in mammals and plants, excess lysine (Lys) is catabolized via saccharopine into α-amino adipic semialdehyde and glutamate by two consecutive enzymes, Lys-ketoglutarate reductase (LKR) and...

Characterization of the Two Saccharopine Dehydrogenase Isozymes of Lysine Catabolism Encoded by the Single Composite AtLKR/SDH Locus of Arabidopsis1

Zhu, Xiaohong, Tang, Guiliang, Galili, Gad

Arabidopsis plants possess a composite AtLKR/SDH locus encoding two different polypeptides involved in lysine catabolism: a bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase...

A T-DNA Insertion Knockout of the Bifunctional Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase Gene Elevates Lysine Levels in Arabidopsis Seeds1

Zhu, Xiaohong, Tang, Guiliang, Granier, Fabienne, Bouchez, David, Galili, Gad

Plants possess both anabolic and catabolic pathways for the essential amino acid lysine (Lys). However, although the biosynthetic pathway was clearly shown to regulate Lys accumulation in plants, the...

Overexpression of a Plasma Membrane Aquaporin in Transgenic Tobacco Improves Plant Vigor under Favorable Growth Conditions but Not under Drought or Salt Stress

Aharon, Refael, Shahak, Yosepha, Wininger, Smadar, Bendov, Rozalina, Kapulnik, Yoram, Galili, Gad

Most of the symplastic water transport in plants occurs via aquaporins, but the extent to which aquaporins contribute to plant water status under favorable growth conditions and abiotic stress is not...

Increased Lysine Synthesis Coupled with a Knockout of Its Catabolism Synergistically Boosts Lysine Content and Also Transregulates the Metabolism of Other Amino Acids in Arabidopsis Seeds

Zhu, Xiaohong, Galili, Gad

To elucidate the relative significance of Lys synthesis and catabolism in determining Lys level in plant seeds, we expressed a bacterial feedback-insensitive dihydrodipicolinate synthase (DHPS) in a...

The Bifunctional LKR/SDH Locus of Plants Also Encodes a Highly Active Monofunctional Lysine-Ketoglutarate Reductase Using a Polyadenylation Signal Located within an Intron1[w]

Tang, Guiliang, Zhu, Xiaohong, Gakiere, Bertrand, Levanony, Hanna, Kahana, Anat, Galili, Gad

Both plants and animals catabolize lysine (Lys) via two consecutive enzymes, Lys-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH), which are linked on a single polypeptide encoded...

Synthesis of the Arabidopsis Bifunctional Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase Enzyme of Lysine Catabolism Is Concertedly Regulated by Metabolic and Stress-Associated Signals1

Stepansky, Asya, Galili, Gad

In plants, excess cellular lysine (Lys) is catabolized into glutamic acid and acetyl-coenzyme A; yet, it is still not clear whether this pathway has other functions in addition to balancing Lys...

Gene-dosage compensation of endosperm proteins in hexaploid wheat Triticum aestivum

Galili, Gad, Levy, Avraham A., Feldman, Moshe

Several aneuploid lines and one intervarietal substitution line of the hexaploid wheat Triticum aestivum (2n = 6x = 42; genomes AABBDD) cv. Chinese Spring were used to study the effects of different...

Lysine Metabolism Is Concurrently Regulated by Synthesis and Catabolism in Both Reproductive and Vegetative Tissues1[w]

Zhu, Xiaohong, Galili, Gad

The functional role of Lys catabolism in balancing Lys levels in plants has only been directly demonstrated in developing seeds. Seed-specific expression of a bacterial feedback-insensitive...

Expression of a Maize Storage Protein Gene in Petunia Plants Is Not Restricted to Seeds 1

Ueng, Peter, Galili, Gad, Sapanara, Victoria, Goldsbrough, Peter B., Dube, Phillip, Beachy, Roger N., ...

Genes encoding maize seed storage proteins, zeins, are expressed in developing endosperm tissue. To determine whether the DNA sequences controlling the developmental expression of these genes are...

The Synthesis of a 19 Kilodalton Zein Protein in Transgenic Petunia Plants 1

Williamson, John D., Galili, Gad, Larkins, Brian A., Gelvin, Stanton B.

Transcriptional fusions composed of a 19 kilodalton zein cDNA, the 5′ flanking region from a β-phaseolin gene, and 3′ flanking regions from either the phaseolin or a 15-kilodalton zein gene were...

Characterization of Polypeptides Corresponding to Clones of Maize Zein mRNAS

Galili, Gad, Kawata, Evelynn E., Larkins, Brian A.

Zeins, the storage proteins of maize (Zea mays) are a complex group of polypeptides encoded by a large multigene family. The α-zein proteins, which account for about 70% of the total, show both size...

Threonine Overproduction in Transgenic Tobacco Plants Expressing a Mutant Desensitized Aspartate Kinase of Escherichia coli1

Shaul, Orit, Galili, Gad

In higher plants, the synthesis of the essential amino acid threonine is regulated primarily by the sensitivity of the first enzyme in its biosynthetic pathway, aspartate kinase, to feedback...

Role of the Amino- and Carboxy-Terminal Regions in the Folding and Oligomerization of Wheat High Molecular Weight Glutenin Subunits 1

Shani, Noam, Steffen-Campbell, Jody D., Anderson, Olin D., Greene, Frank C., Galili, Gad

The high molecular weight glutenin subunits are considered one of the most important components of wheat (Triticum aestivum) gluten, but their structure and interactions with other gluten proteins...

Evidence for the Presence of Two Different Types of Protein Bodies in Wheat Endosperm

Rubin, Regina, Levanony, Hanna, Galili, Gad

Storage proteins of wheat grains (Triticum L. em Thell) are deposited in protein bodies inside vacuoles. However, the subcellular sites and mechanisms of their aggregation into protein bodies are not...

Expression of an Arabidopsis Aspartate Kinase/Homoserine Dehydrogenase Gene Is Metabolically Regulated by Photosynthesis-Related Signals but Not by Nitrogenous Compounds1

Zhu-Shimoni, Judith X., Galili, Gad

Although the control of carbon fixation and nitrogen assimilation has been studied in detail, relatively little is known about the regulation of carbon and nitrogen flow into amino acids. In this...

Purification and Characterization of Bifunctional Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase from Developing Soybean Seeds1

Miron, Daphna, Ben-Yaacov, Sari, Reches, Dalit, Schupper, Avigail, Galili, Gad

Both in mammals and plants, excess lysine (Lys) is catabolized via saccharopine into α-amino adipic semialdehyde and glutamate by two consecutive enzymes, Lys-ketoglutarate reductase (LKR) and...

Characterization of the Two Saccharopine Dehydrogenase Isozymes of Lysine Catabolism Encoded by the Single Composite AtLKR/SDH Locus of Arabidopsis1

Zhu, Xiaohong, Tang, Guiliang, Galili, Gad

Arabidopsis plants possess a composite AtLKR/SDH locus encoding two different polypeptides involved in lysine catabolism: a bifunctional lysine-ketoglutarate reductase/saccharopine dehydrogenase...

A T-DNA Insertion Knockout of the Bifunctional Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase Gene Elevates Lysine Levels in Arabidopsis Seeds1

Zhu, Xiaohong, Tang, Guiliang, Granier, Fabienne, Bouchez, David, Galili, Gad

Plants possess both anabolic and catabolic pathways for the essential amino acid lysine (Lys). However, although the biosynthetic pathway was clearly shown to regulate Lys accumulation in plants, the...

Overexpression of a Plasma Membrane Aquaporin in Transgenic Tobacco Improves Plant Vigor under Favorable Growth Conditions but Not under Drought or Salt Stress

Aharon, Refael, Shahak, Yosepha, Wininger, Smadar, Bendov, Rozalina, Kapulnik, Yoram, Galili, Gad

Most of the symplastic water transport in plants occurs via aquaporins, but the extent to which aquaporins contribute to plant water status under favorable growth conditions and abiotic stress is not...

Increased Lysine Synthesis Coupled with a Knockout of Its Catabolism Synergistically Boosts Lysine Content and Also Transregulates the Metabolism of Other Amino Acids in Arabidopsis Seeds

Zhu, Xiaohong, Galili, Gad

To elucidate the relative significance of Lys synthesis and catabolism in determining Lys level in plant seeds, we expressed a bacterial feedback-insensitive dihydrodipicolinate synthase (DHPS) in a...

The Bifunctional LKR/SDH Locus of Plants Also Encodes a Highly Active Monofunctional Lysine-Ketoglutarate Reductase Using a Polyadenylation Signal Located within an Intron1[w]

Tang, Guiliang, Zhu, Xiaohong, Gakiere, Bertrand, Levanony, Hanna, Kahana, Anat, Galili, Gad

Both plants and animals catabolize lysine (Lys) via two consecutive enzymes, Lys-ketoglutarate reductase (LKR) and saccharopine dehydrogenase (SDH), which are linked on a single polypeptide encoded...

Synthesis of the Arabidopsis Bifunctional Lysine-Ketoglutarate Reductase/Saccharopine Dehydrogenase Enzyme of Lysine Catabolism Is Concertedly Regulated by Metabolic and Stress-Associated Signals1

Stepansky, Asya, Galili, Gad

In plants, excess cellular lysine (Lys) is catabolized into glutamic acid and acetyl-coenzyme A; yet, it is still not clear whether this pathway has other functions in addition to balancing Lys...

Gene-dosage compensation of endosperm proteins in hexaploid wheat Triticum aestivum

Galili, Gad, Levy, Avraham A., Feldman, Moshe

Several aneuploid lines and one intervarietal substitution line of the hexaploid wheat Triticum aestivum (2n = 6x = 42; genomes AABBDD) cv. Chinese Spring were used to study the effects of different...

Lysine Metabolism Is Concurrently Regulated by Synthesis and Catabolism in Both Reproductive and Vegetative Tissues1[w]

Zhu, Xiaohong, Galili, Gad

The functional role of Lys catabolism in balancing Lys levels in plants has only been directly demonstrated in developing seeds. Seed-specific expression of a bacterial feedback-insensitive...

Expression of a Maize Storage Protein Gene in Petunia Plants Is Not Restricted to Seeds 1

Ueng, Peter, Galili, Gad, Sapanara, Victoria, Goldsbrough, Peter B., Dube, Phillip, Beachy, Roger N., ...

Genes encoding maize seed storage proteins, zeins, are expressed in developing endosperm tissue. To determine whether the DNA sequences controlling the developmental expression of these genes are...

The Synthesis of a 19 Kilodalton Zein Protein in Transgenic Petunia Plants 1

Williamson, John D., Galili, Gad, Larkins, Brian A., Gelvin, Stanton B.

Transcriptional fusions composed of a 19 kilodalton zein cDNA, the 5′ flanking region from a β-phaseolin gene, and 3′ flanking regions from either the phaseolin or a 15-kilodalton zein gene were...

Characterization of Polypeptides Corresponding to Clones of Maize Zein mRNAS

Galili, Gad, Kawata, Evelynn E., Larkins, Brian A.

Zeins, the storage proteins of maize (Zea mays) are a complex group of polypeptides encoded by a large multigene family. The α-zein proteins, which account for about 70% of the total, show both size...

Threonine Overproduction in Transgenic Tobacco Plants Expressing a Mutant Desensitized Aspartate Kinase of Escherichia coli1

Shaul, Orit, Galili, Gad

In higher plants, the synthesis of the essential amino acid threonine is regulated primarily by the sensitivity of the first enzyme in its biosynthetic pathway, aspartate kinase, to feedback...

Role of the Amino- and Carboxy-Terminal Regions in the Folding and Oligomerization of Wheat High Molecular Weight Glutenin Subunits 1

Shani, Noam, Steffen-Campbell, Jody D., Anderson, Olin D., Greene, Frank C., Galili, Gad

The high molecular weight glutenin subunits are considered one of the most important components of wheat (Triticum aestivum) gluten, but their structure and interactions with other gluten proteins...

Evidence for the Presence of Two Different Types of Protein Bodies in Wheat Endosperm

Rubin, Regina, Levanony, Hanna, Galili, Gad

Storage proteins of wheat grains (Triticum L. em Thell) are deposited in protein bodies inside vacuoles. However, the subcellular sites and mechanisms of their aggregation into protein bodies are not...

Arabidopsis Seed Development and Germination Is Associated with Temporally Distinct Metabolic Switches1[W]

Fait, Aaron, Angelovici, Ruthie, Less, Hadar, Ohad, Itzhak, Urbanczyk-Wochniak, Ewa, Fernie, Alisdair R., ...

While the metabolic networks in developing seeds during the period of reserve accumulation have been extensively characterized, much less is known about those present during seed desiccation and...

An autophagy-associated Atg8 protein is involved in the responses of Arabidopsis seedlings to hormonal controls and abiotic stresses

Slavikova, Silvia, Ufaz, Shai, Avin-Wittenberg, Tamar, Levanony, Hanna, Galili, Gad

Eukaryotes contain a ubiquitous family of autophagy-associated Atg8 proteins. In animal cells, these proteins have multiple functions associated with growth, cancer, and degenerative diseases, but...

Principal Transcriptional Programs Regulating Plant Amino Acid Metabolism in Response to Abiotic Stresses1[W][OA]

Less, Hadar, Galili, Gad

Using a bioinformatics analysis of public Arabidopsis (Arabidopsis thaliana) microarray data, we propose here a novel regulatory program, combining transcriptional and posttranslational controls,...