Gail Tomlinson

Genetic variation in insulin-like growth factor signaling genes and breast cancer risk among BRCA1and BRCA2carriers (2009)

Neuhausen, Susan L, Brummel, Sean, Ding, Yuan, Singer, Christian F, Pfeiler, Georg, Lynch, Henry T, ...

Abstract Introduction Women who carry mutations in BRCA1 and BRCA2 have a substantially increased risk of developing breast cancer as compared with the general population. However, risk estimates...

Pretest Prediction of BRCA1 or BRCA2 Mutation by Risk Counselors and the Computer Model BRCAPRO (2002)

Euhus, David M., Smith, Kristin C., Robinson, Linda, Stucky, Amy, Olopade, Olufunmilayo I., Cummings, Shelly, ...

Background: Because BRCA gene mutation testing is costly, occasionally uninformative, and frequently associated with ethical and legal issues, careful patient selection is required prior to testing....

Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells (1998)

Chen, Junjie, Silver, Daniel P., Walpita, Deepika, Cantor, Sharon B., Gazdar, Adi F., Tomlinson, Gail, ...

BRCA1 and BRCA2 account for most cases of familial, early onset breast and/or ovarian cancer and encode products that each interact with hRAD51. Results presented here show that BRCA1 and BRCA2...

Common Breast Cancer-Predisposition Alleles Are Associated with Breast Cancer Risk in BRCA1 and BRCA2 Mutation Carriers

Antoniou, Antonis C., Spurdle, Amanda B., Sinilnikova, Olga M., Healey, Sue, Pooley, Karen A., Schmutzler, Rita K., ...

Germline mutations in BRCA1 and BRCA2 confer high risks of breast cancer. However, evidence suggests that these risks are modified by other genetic or environmental factors that cluster in families....