Gan Wang

Induction of endogenous γ-globin gene expression with decoy oligonucleotide targeting Oct-1 transcription factor consensus sequence (2009)

Xu, Xiaoxin S, Hong, Xin, Wang, Gan

Abstract Human β-globin disorders are relatively common genetic diseases cause by mutations in the β-globin gene. Increasing the expression of the γ -globin gene has great benefits in reducing...

The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation (2004)

Wang, Gan, Chuang, Lynn, Zhang, Xiaohong, Colton, Stephanie, Dombkowski, Alan, Reiners, John, ...

XPC is an important DNA damage recognition protein involved in DNA nucleotide excision repair. We have studied the role of the XPC protein in cisplatin treatment‐mediated cell cycle regulation....

Defining the function of XPC protein in psoralen and cisplatin-mediated DNA repair and mutagenesis (2003)

Chen, Zhiwen, Xu, Xiaoxin Susan, Yang, Jin, Wang, Gan

DNA damage recognition plays an important role in DNA repair and mutagenesis. Failure to recognize DNA damage may lead to DNA replication without damage repair as well as mutation accumulation....

Defining the function of XPC protein in psoralen and cisplatin-mediated DNA repair and mutagenesis (2003)

Chen, Zhiwen, Xu, Xiaoxin Susan, Yang, Jin, Wang, Gan

DNA damage recognition plays an important role in DNA repair and mutagenesis. Failure to recognize DNA damage may lead to DNA replication without damage repair as well as mutation accumulation....

Defining the function of XPC protein in psoralen and cisplatin-mediated DNA repair and mutagenesis (2003)

Chen, Zhiwen, Xu, Xiaoxin Susan, Yang, Jin, Wang, Gan

DNA damage recognition plays an important role in DNA repair and mutagenesis. Failure to recognize DNA damage may lead to DNA replication without damage repair as well as mutation accumulation....

RAPD (arbitrary primer) PCR is more sensitive than multilocus enzyme electrophoresis for distinguishing related bacterial strains (1993)

Wang, Gan, Whittam, Thomas S., Berg, Claire M., Berg, Douglas E.

The RAPD (random amplified polymorphic DNA) fingerprinting method, which utilizes low stringency PCR amplification with single primers of arbitrary sequence to generate strain-specific arrays of...

Detection and determination of oligonucleotide triplex formation-mediated transcription-coupled DNA repair in HeLa nuclear extracts

Wang, Gan, Chen, Zhiwen, Zhang, Shijun, Wilson, Glenn L., Jing, Kai

Transcription-coupled repair (TCR) plays an important role in removing DNA damage from actively transcribed genes. It has been speculated that TCR is the most important mechanism for repairing DNA...

The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation

Wang, Gan, Chuang, Lynn, Zhang, Xiaohong, Colton, Stephanie, Dombkowski, Alan, Reiners, John, ...

XPC is an important DNA damage recognition protein involved in DNA nucleotide excision repair. We have studied the role of the XPC protein in cisplatin treatment-mediated cell cycle regulation....

Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesis.

Chen, Zhiwen, Xu, Xiaoxin Susan, Harrison, Jason, Wang, Gan

Many commonly used drugs, such as psoralen and cisplatin, can generate a very unique type of DNA damage, namely ICL (interstrand cross-link). An ICL can severely block DNA replication and...

Detection and determination of oligonucleotide triplex formation-mediated transcription-coupled DNA repair in HeLa nuclear extracts

Wang, Gan, Chen, Zhiwen, Zhang, Shijun, Wilson, Glenn L., Jing, Kai

Transcription-coupled repair (TCR) plays an important role in removing DNA damage from actively transcribed genes. It has been speculated that TCR is the most important mechanism for repairing DNA...

The initiative role of XPC protein in cisplatin DNA damaging treatment-mediated cell cycle regulation

Wang, Gan, Chuang, Lynn, Zhang, Xiaohong, Colton, Stephanie, Dombkowski, Alan, Reiners, John, ...

XPC is an important DNA damage recognition protein involved in DNA nucleotide excision repair. We have studied the role of the XPC protein in cisplatin treatment-mediated cell cycle regulation....

Defining the function of xeroderma pigmentosum group F protein in psoralen interstrand cross-link-mediated DNA repair and mutagenesis.

Chen, Zhiwen, Xu, Xiaoxin Susan, Harrison, Jason, Wang, Gan

Many commonly used drugs, such as psoralen and cisplatin, can generate a very unique type of DNA damage, namely ICL (interstrand cross-link). An ICL can severely block DNA replication and...

Induction of endogenous γ-globin gene expression with decoy oligonucleotide targeting Oct-1 transcription factor consensus sequence

Xu, Xiaoxin S, Hong, Xin, Wang, Gan

Human β-globin disorders are relatively common genetic diseases cause by mutations in the β-globin gene. Increasing the expression of the γ-globin gene has great benefits in reducing complications...