Garret M. Hampton

Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer

Welsh, John B., Zarrinkar, Patrick P., Sapinoso, Lisa M., Kern, Suzanne G., Behling, Cynthia A., Monk, Bradley J., ...

Epithelial ovarian cancer is the leading cause of death from gynecologic cancer, in part because of the lack of effective early detection methods. Although alterations of several genes, such as...

Large-scale analysis of the human and mouse transcriptomes

Su, Andrew I., Cooke, Michael P., Ching, Keith A., Hakak, Yaron, Walker, John R., Wiltshire, Tim, ...

High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments...

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

Welsh, John B., Sapinoso, Lisa M., Kern, Suzanne G., Brown, David A., Liu, Tao, Bauskin, Asne R., ...

Genetic alterations in tumor cells often lead to the emergence of growth-stimulatory autocrine and paracrine signals, involving overexpression of secreted peptide growth factors, cytokines, and...

Arrays of Arrays for High-Throughput Gene Expression Profiling

Zarrinkar, Patrick P., Mainquist, James K., Zamora, Matthew, Stern, David, Welsh, John B., Sapinoso, Lisa M., ...

Gene expression profiling using DNA arrays is rapidly becoming an essential tool for research and drug discovery and may soon play a central role in disease diagnosis. Although it is possible to make...

A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase

Collins, Cynthia S., Hong, Jiyong, Sapinoso, Lisa, Zhou, Yingyao, Liu, Zheng, Micklash, Kenneth, ...

Cell motility is a complex biological process, involved in development, inflammation, homeostasis, and pathological processes such as the invasion and metastatic spread of cancer. Here, we describe a...

Altered Expression of TFF-1 and CES-2 in Barrett's Esophagus and Associated Adenocarcinomas1

Fox, Charles A, Sapinoso, Lisa M, Zhang, Hong, Zhang, Wanghai, McLeod, Howard L, Petroni, Gina R, ...

Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue. We utilized gene expression profiling to compare...

Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer

Welsh, John B., Zarrinkar, Patrick P., Sapinoso, Lisa M., Kern, Suzanne G., Behling, Cynthia A., Monk, Bradley J., ...

Epithelial ovarian cancer is the leading cause of death from gynecologic cancer, in part because of the lack of effective early detection methods. Although alterations of several genes, such as...

Large-scale analysis of the human and mouse transcriptomes

Su, Andrew I., Cooke, Michael P., Ching, Keith A., Hakak, Yaron, Walker, John R., Wiltshire, Tim, ...

High-throughput gene expression profiling has become an important tool for investigating transcriptional activity in a variety of biological samples. To date, the vast majority of these experiments...

Large-scale delineation of secreted protein biomarkers overexpressed in cancer tissue and serum

Welsh, John B., Sapinoso, Lisa M., Kern, Suzanne G., Brown, David A., Liu, Tao, Bauskin, Asne R., ...

Genetic alterations in tumor cells often lead to the emergence of growth-stimulatory autocrine and paracrine signals, involving overexpression of secreted peptide growth factors, cytokines, and...

Arrays of Arrays for High-Throughput Gene Expression Profiling

Zarrinkar, Patrick P., Mainquist, James K., Zamora, Matthew, Stern, David, Welsh, John B., Sapinoso, Lisa M., ...

Gene expression profiling using DNA arrays is rapidly becoming an essential tool for research and drug discovery and may soon play a central role in disease diagnosis. Although it is possible to make...

A small interfering RNA screen for modulators of tumor cell motility identifies MAP4K4 as a promigratory kinase

Collins, Cynthia S., Hong, Jiyong, Sapinoso, Lisa, Zhou, Yingyao, Liu, Zheng, Micklash, Kenneth, ...

Cell motility is a complex biological process, involved in development, inflammation, homeostasis, and pathological processes such as the invasion and metastatic spread of cancer. Here, we describe a...

Altered Expression of TFF-1 and CES-2 in Barrett's Esophagus and Associated Adenocarcinomas1

Fox, Charles A, Sapinoso, Lisa M, Zhang, Hong, Zhang, Wanghai, McLeod, Howard L, Petroni, Gina R, ...

Identification of biomarkers to recognize individuals with Barrett's esophagus (BE) predisposed to develop malignancy is currently a pressing issue. We utilized gene expression profiling to compare...

Large Scale Molecular Analysis Identifies Genes with Altered Expression in Salivary Adenoid Cystic Carcinoma

Frierson, Henry F., El-Naggar, Adel K., Welsh, John B., Sapinoso, Lisa M., Su, Andrew I., Cheng, Jun, ...

Salivary gland cancers comprise a heterogeneous group of neoplasms whose biological and clinical characteristics differ considerably from those of mucosal squamous cell carcinomas of the head and...

Cdc6 and Cyclin E2 Are PTEN-Regulated Genes Associated with Human Prostate Cancer Metastasis1

Wu, Zhong, Cho, HyungJun, Hampton, Garret M, Theodorescu, Dan

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is frequently inactivated in metastatic prostate cancer, yet the molecular consequences of this and their association with the...