Gary G. Koch

A Multivariate Approach to Sample Size Calculations for Thorough QT Studies (2009)

Suraj P. An, Sharon C. Murray, Gary G. Koch

Thorough QT studies are becoming a necessary part of the clinical profile of existing and investigational new drugs. The E14 guidelines mandate performing a thorough QT study on any non antiarrythmic...

Sample Size Calculations for Crossover Thorough QT Studies: Non-inferiority and Assay Sensitivity (2009)

Suraj P. An, Sharon C. Murray, Gary G. Koch

The cost involved in running a ‘thorough QT/QTc study ’ is substantial and an adverse outcome of the study can be detrimental to the safety profile of the drug, hence sample size calculations...

Community Influenza Activity and Risk of Acute Influenza-like Illness Episodes among Healthy Unvaccinated Pregnant and Postpartum Women (2006)

Lindsay, Lisa, Jackson, Lisa A., Savitz, David A., Weber, David J., Koch, Gary G., Kong, Lan, ...

This study investigated the relation between weekly levels of influenza activity and the risk of acute influenza-like illness episodes among 8,323 healthy pregnant and postpartum women enrolled in a...

Analyzing Repeated Measures Marginal Models on Sample Surveys with Resampling Methods (2005)

James D. Knoke, Christy M. Anderson, Gary G. Koch

Packaged statistical software for analyzing categorical, repeated measures marginal models on sample survey data with binary covariates does not appear to be available. Consequently, this report...

Statistical Approaches to Effectiveness Measurement and Outcome-Driven Re-Randomizations in the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Studies (2003)

Davis, Sonia M., Koch, Gary G., Davis, C. E., LaVange, Lisa M.

The design of the Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) schizophrenia and Alzheimer's disease studies pose several statistical challenges, including issues related to...

Increasing low income employee participation in a worksite health promotion program: a comparison of three common strategies (1996)

Wong, Yueh-ti, Bauman, Karl E., Koch, Gary G.

The relative effectiveness of three common strategies to increase participation in worksite health promotion programs was assessed. The interventions, designed for low income employees, were (1)...

ATYPICAL METAPLASIA AND INCIDENCE OF BRONCHOGENIC CARCINOMA (1990)

VINE, MARILYN F., SCHOENBACH, VICTOR J., HULKA, BARBARA S., KOCH, GARY G., SAMSA, GREGORY

The prognostic implication of atypical squamous metaplasia of the respiratory tract has been uncertain, especially for mild atypia. The relation between degree of severity of atypical metaplasia as...

A media-based campaign to encourage personal communication among adolescents about not smoking cigarettes: participation, selection and consequences (1989)

Bauman, Karl E., Padgett, Connie A., Koch, Gary G.

Theory suggests that mass media will be more effective if they stimulate interpersonal communication, and research suggests that adolescent smoking is related to the attitudes and behavior of their...

ON THE MEASUREMENT OF TOBACCO USE BY ADOLESCENTS: VALIDITY OF SELF-REPORTS OF SMOKELESS TOBACCO USE AND VALIDITY OF COTININE AS AN INDICATOR OF CIGARETTE SMOKING (1989)

BAUMAN, KARL E., KOCH, GARY G., BRYAN, ELIZABETH S, HALEY, NANCY J, DOWNTON, MARIA I., ORLANDI, MARIO A.

This study assessed the validtty of self-reporb of smokeless tobacco use by adolescents and the validity of cotinine as a measure of adolescent cigarette smoking. For a sample of 1,854 persons aged...

Models of Adult Day Care: Findings From a National Survey (1989)

Weissert, William G., Elston, Jennifer M., Bolda, Elise J., Cready, Cynthia M., Zelman, William N., Sloane, Phil D., ...

We examined a nationally representative sample of 60 adult day care centers to describe the state of this evolving care modality after a decade's growth. Results indicate that day care centers can be...

VALIDITY OF SELF-REPORTS AND DESCRIPTIVE AND ANALYTICAL CONCLUSIONS: THE CASE OF CIGARETTE SMOKING BY ADOLESCENTS AND THEIR MOTHERS (1983)

BAUMAN, KARL E., KOCH, GARY G.

Bauman, K. E. (Dept. of Maternal and Child Health, School of Public Health, U. of North Carolina, Chapel Hill, NC 27514) and G. G. Koch. Validity of self-reports and descriptive and analytical...

A computer program for testing average partial association in three-way contingency tables (PARCAT) (1979)

Landis, J. Richard, Cooper, Murray M., Kennedy, Thomas, Koch, Gary G.

PARCAT is a computer program which implements alternative tests for average partial association in three-way contingency tables within the framework of the product multiple hypergeometric probability...

A computer program for multivariate ratio analysis (MISCAT) (1978)

Stanish, William M., Koch, Gary G., Landis, J. Richard

Analysts must deal frequently with missing data in multivariate analysis. In such cases, estimating the covariance maxtrix V of the dependent variables usually involves initial estimation and...

A computer program for the generalized chi-square analysis of competing risks grouped survival data (CRISCAT) (1978)

Stanish, William M., Chi, G. Y. H., Johnson, William D., Koch, Gary G., Landis, J. Richard, Liu-Chi, Shelley

CRISCAT is a computer program for the analysis of grouped survival data with competing risks via weighted least squares methods. Competing risks adjustments are obtained from general matrix...

A computer program for the generalized chi-square analysis of categorical data using weighted least squares (GENCAT) (1976)

Landis, J. Richard, Stanish, William M., Freeman, Jean L., Koch, Gary G.

GENCAT is a computer program which implements an extremely general methodology for the analysis of multivariate categorical data. This approach essentially involves the construction of test...

Analyzing Panel Data with Uncontrolled Attrition (1974)

Lehnen, Robert G., Koch, Gary G.

Three-wave panel data collected during the 1968 presidential election campaign in Florida and North Carolina are analyzed on the basis of the partial candidate preference information available for...

Analysis of Qualitative Data: Linear Functions

Johnson, William D., Koch, Gary G.

A procedure is described for fitting linear models to categorical data obtained by stratified random sampling. The method makes it possible to compute estimates of variance and to test certain types...

Analysis of Qualitative Data: Linear Functions

Johnson, William D., Koch, Gary G.

A procedure is described for fitting linear models to categorical data obtained by stratified random sampling. The method makes it possible to compute estimates of variance and to test certain types...

Analyzing Repeated Measures Marginal Models on Sample Surveys with Resampling Methods

James D. Knoke, Christy M. Anderson, Gary G. Koch

Packaged statistical software for analyzing categorical, repeated measures marginal models on sample survey data with binary covariates does not appear to be available. Consequently, this report...