Accommodating Covariates in ROC Analysis (2008)
Janes, Holly, Longton, Gary M., Pepe, Margaret
Classification accuracy is the ability of a marker or diagnostic test to discriminate between two groups of individuals, cases and controls, and is commonly summarized using the receiver operating...
Estimation and Comparison of Receiver Operating Characteristic Curves (2008)
Pepe, Margaret, Longton, Gary M., Janes, Holly
The receiver operating characteristic (ROC) curve displays the capacity of a marker or diagnostic test to discriminate between two groups of subjects, cases versus controls. We present a...
Accommodating Covariates in ROC Analysis (2008)
Janes, Holly, Longton, Gary M., Pepe, Margaret
Classification accuracy is the ability of a marker or diagnostic test to discriminate between two groups of individuals, cases and controls, and is commonly summarized using the receiver operating...
Estimation and Comparison of Receiver Operating Characteristic Curves (2008)
Pepe, Margaret, Longton, Gary M., Janes, Holly
The receiver operating characteristic (ROC) curve displays the capacity of a marker or diagnostic test to discriminate between two groups of subjects, cases versus controls. We present a...
Accommodating Covariates in ROC Analysis (2008)
Janes, Holly, Longton, Gary M., Pepe, Margaret
Classification accuracy is the ability of a marker or diagnostic test to discriminate between two groups of individuals, cases and controls, and is commonly summarized using the receiver operating...
Estimation and Comparison of Receiver Operating Characteristic Curves (2008)
Pepe, Margaret, Longton, Gary M., Janes, Holly
The receiver operating characteristic (ROC) curve displays the capacity of a marker or diagnostic test to discriminate between two groups of subjects, cases versus controls. We present a...
Accommodating Covariates in ROC Analysis (2008)
Janes, Holly, Longton, Gary M., Pepe, Margaret
Classification accuracy is the ability of a marker or diagnostic test to discriminate between two groups of individuals, cases and controls, and is commonly summarized using the receiver operating...
Estimation and Comparison of Receiver Operating Characteristic Curves (2008)
Pepe, Margaret, Longton, Gary M., Janes, Holly
The receiver operating characteristic (ROC) curve displays the capacity of a marker or diagnostic test to discriminate between two groups of subjects, cases versus controls. We present a...
Integrating the Predictiveness of a Marker with its Performance as a Classifier (2006)
Pepe, Margaret S., Feng, Ziding, Huang, Ying, Longton, Gary M., Prentice, Ross, Thompson, Ian M, ...
There are two popular statistical approaches to biomarker evaluation. One models the risk of disease (or disease outcome) using, for example, logistic regression. A marker is useful if it has a...
Integrating the Predictiveness of a Marker with its Performance as a Classifier (2006)
Pepe, Margaret S., Feng, Ziding, Huang, Ying, Longton, Gary M., Prentice, Ross, Thompson, Ian M, ...
There are two popular statistical approaches to biomarker evaluation. One models the risk of disease (or disease outcome) using, for example, logistic regression. A marker is useful if it has a...
Integrating the Predictiveness of a Marker with its Performance as a Classifier (2006)
Pepe, Margaret S., Feng, Ziding, Huang, Ying, Longton, Gary M., Prentice, Ross, Thompson, Ian M, ...
There are two popular statistical approaches to biomarker evaluation. One models the risk of disease (or disease outcome) using, for example, logistic regression. A marker is useful if it has a...
Integrating the Predictiveness of a Marker with its Performance as a Classifier (2006)
Pepe, Margaret S., Feng, Ziding, Huang, Ying, Longton, Gary M., Prentice, Ross, Thompson, Ian M, ...
There are two popular statistical approaches to biomarker evaluation. One models the risk of disease (or disease outcome) using, for example, logistic regression. A marker is useful if it has a...
Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic or Prognostic Marker (2005)
Pepe, Margaret S., Janes, Holly, Longton, Gary M., Leisenring, Wendy, Newcomb, Polly
A marker that is strongly associated with outcome (or disease) is often assumed to be effective for classifying individuals according to their current or future outcome. However, for this to be true,...
Standardizing Markers to Evaluate and Compare their Performances (2005)
Pepe, Margaret S., Longton, Gary M.
Introduction: Markers that purport to distinguish subjects with a condition from those without a condition must be evaluated rigorously for their classification accuracy. A single approach to...
Combining Predictors for Classification using the Area Under the ROC Curve (2005)
Pepe, Margaret S., Cai, Tianxi, Zhang, Zheng, Longton, Gary M.
No single biomarker for cancer is considered adequately sensitive and specific for cancer screening. It is expected that the results of multiple markers will need to be combined in order to yield...
Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic or Prognostic Marker (2005)
Pepe, Margaret S., Janes, Holly, Longton, Gary M., Leisenring, Wendy, Newcomb, Polly
A marker that is strongly associated with outcome (or disease) is often assumed to be effective for classifying individuals according to their current or future outcome. However, for this to be true,...
Standardizing Markers to Evaluate and Compare their Performances (2005)
Pepe, Margaret S., Longton, Gary M.
Introduction: Markers that purport to distinguish subjects with a condition from those without a condition must be evaluated rigorously for their classification accuracy. A single approach to...
Combining Predictors for Classification using the Area Under the ROC Curve (2005)
Pepe, Margaret S., Cai, Tianxi, Zhang, Zheng, Longton, Gary M.
No single biomarker for cancer is considered adequately sensitive and specific for cancer screening. It is expected that the results of multiple markers will need to be combined in order to yield...
Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic or Prognostic Marker (2005)
Pepe, Margaret S., Janes, Holly, Longton, Gary M., Leisenring, Wendy, Newcomb, Polly
A marker that is strongly associated with outcome (or disease) is often assumed to be effective for classifying individuals according to their current or future outcome. However, for this to be true,...
Standardizing Markers to Evaluate and Compare their Performances (2005)
Pepe, Margaret S., Longton, Gary M.
Introduction: Markers that purport to distinguish subjects with a condition from those without a condition must be evaluated rigorously for their classification accuracy. A single approach to...
Combining Predictors for Classification using the Area Under the ROC Curve (2005)
Pepe, Margaret S., Cai, Tianxi, Zhang, Zheng, Longton, Gary M.
No single biomarker for cancer is considered adequately sensitive and specific for cancer screening. It is expected that the results of multiple markers will need to be combined in order to yield...
Limitations of the Odds Ratio in Gauging the Performance of a Diagnostic or Prognostic Marker (2005)
Pepe, Margaret S., Janes, Holly, Longton, Gary M., Leisenring, Wendy, Newcomb, Polly
A marker that is strongly associated with outcome (or disease) is often assumed to be effective for classifying individuals according to their current or future outcome. However, for this to be true,...
Standardizing Markers to Evaluate and Compare their Performances (2005)
Pepe, Margaret S., Longton, Gary M.
Introduction: Markers that purport to distinguish subjects with a condition from those without a condition must be evaluated rigorously for their classification accuracy. A single approach to...
Combining Predictors for Classification using the Area Under the ROC Curve (2005)
Pepe, Margaret S., Cai, Tianxi, Zhang, Zheng, Longton, Gary M.
No single biomarker for cancer is considered adequately sensitive and specific for cancer screening. It is expected that the results of multiple markers will need to be combined in order to yield...
Selecting Differentially Expressed Genes from Microarray Experiments (2003)
Pepe, Margaret S., Longton, Gary M., Anderson, Garnet L., Schummer, Michel
High throughput technologies, such as gene expression arrays and protein mass spectrometry, allow one to simultaneously evaluate thousands of potential biomarkers that distinguish different tissue...
Selecting Differentially Expressed Genes from Microarray Experiments (2003)
Pepe, Margaret S., Longton, Gary M., Anderson, Garnet L., Schummer, Michel
High throughput technologies, such as gene expression arrays and protein mass spectrometry, allow one to simultaneously evaluate thousands of potential biomarkers that distinguish different tissue...
Selecting Differentially Expressed Genes from Microarray Experiments (2003)
Pepe, Margaret S., Longton, Gary M., Anderson, Garnet L., Schummer, Michel
High throughput technologies, such as gene expression arrays and protein mass spectrometry, allow one to simultaneously evaluate thousands of potential biomarkers that distinguish different tissue...
Selecting Differentially Expressed Genes from Microarray Experiments (2003)
Pepe, Margaret S., Longton, Gary M., Anderson, Garnet L., Schummer, Michel
High throughput technologies, such as gene expression arrays and protein mass spectrometry, allow one to simultaneously evaluate thousands of potential biomarkers that distinguish different tissue...
Galipeau, Patricia C., Prevo, Laura J., Sanchez, Carissa A., Longton, Gary M., Reid, Brian J.
BACKGROUND: Abnormalities involving the p16 (also known as cyclin-dependent kinase N2 [CDKN2], p16 [INK4a], or MTS1) and p53 (also known as TP53) tumor suppressor genes are highly...
Grosse-Wilde, Anne, Voloshanenko, Oksana, Bailey, S. Lawrence, Longton, Gary M., Schaefer, Uta, Csernok, Andreea I., ...
TRAIL is a promising anticancer agent due to its ability to selectively induce apoptosis in established tumor cell lines but not nontransformed cells. Herein, we demonstrate a role for the...
Speaking Stata: Distinct observations
Nicholas J. Cox, Gary M. Longton
Distinct observations are those different with respect to one or more variables, considered either individually or jointly. Distinctness is thus a key aspect of the similarity or difference of...