[The Private Life of Plants] (1995)
Lucas, Neil (dir.), Salisbury, Mike (prod. De La Serie), Attenborough, David (guión), Kirby, Richard (fotografía), Thurston, Gavin (fotografía), Grassby-Lewis, Richard (música)
A lo largo de este programa se muestra la gran capacidad de adaptación de las plantas ante las condiciones adversas: un desastre natural en que se pierden árboles milenarios puede dar oportunidad...
[The Private Life of Plants] (1995)
Lucas, Neil (dir.), Salisbury, Mike (prod. De La Serie), Attenborough, David (guión), Kirby, Richard (fotografía), Thurston, Gavin (fotografía), Grassby-Lewis, Richard (música)
A lo largo de este programa se muestra la gran capacidad de adaptación de las plantas ante las condiciones adversas: un desastre natural en que se pierden árboles milenarios puede dar oportunidad...
Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo
Corada, Monica, Mariotti, Massimo, Thurston, Gavin, Smith, Kelly, Kunkel, Robin, Brockhaus, Manfred, ...
In the present paper, we characterize an antibody, mAb BV13, directed to mouse vascular endothelial (VE)-cadherin, a major adhesive protein of interendothelial adherens junctions. When added to...
Veikkola, Tanja, Jussila, Lotta, Makinen, Taija, Karpanen, Terhi, Jeltsch, Michael, Petrova, Tatiana V., ...
Vascular endothelial growth factor receptor-3 (VEGFR-3) has an essential role in the development of embryonic blood vessels; however, after midgestation its expression becomes restricted mainly to...
Ozawa, Clare R., Banfi, Andrea, Glazer, Nicole L., Thurston, Gavin, Springer, Matthew L., Kraft, Peggy E., ...
Use of long-term constitutive expression of VEGF for therapeutic angiogenesis may be limited by the growth of abnormal blood vessels and hemangiomas. We investigated the relationship between VEGF...
Gale, Nicholas W., Dominguez, Melissa G., Noguera, Irene, Pan, Li, Hughes, Virginia, Valenzuela, David M., ...
Vascular development depends on the highly coordinated actions of a variety of angiogenic regulators, most of which apparently act downstream of vascular endothelial growth factor (VEGF). One...
Elson, David A., Thurston, Gavin, Huang, L. Eric, Ginzinger, David G., McDonald, Donald M., Johnson, Randall S., ...
Hypoxia-inducible factor-1α (HIF-1α) transactivates genes required for energy metabolism and tissue perfusion and is necessary for embryonic development and tumor explant growth. HIF-1α is...
Complementary actions of VEGF and Angiopoietin-1 on blood vessel growth and leakage*
Vascular endothelial growth factor (VEGF) and Angiopoietins are families of vascular-specific growth factors that regulate blood vessel growth, maturation and function. To learn more about the...
Vascular endothelial–cadherin is an important determinant of microvascular integrity in vivo
Corada, Monica, Mariotti, Massimo, Thurston, Gavin, Smith, Kelly, Kunkel, Robin, Brockhaus, Manfred, ...
In the present paper, we characterize an antibody, mAb BV13, directed to mouse vascular endothelial (VE)-cadherin, a major adhesive protein of interendothelial adherens junctions. When added to...
Veikkola, Tanja, Jussila, Lotta, Makinen, Taija, Karpanen, Terhi, Jeltsch, Michael, Petrova, Tatiana V., ...
Vascular endothelial growth factor receptor-3 (VEGFR-3) has an essential role in the development of embryonic blood vessels; however, after midgestation its expression becomes restricted mainly to...
Elson, David A., Thurston, Gavin, Huang, L. Eric, Ginzinger, David G., McDonald, Donald M., Johnson, Randall S., ...
Hypoxia-inducible factor-1α (HIF-1α) transactivates genes required for energy metabolism and tissue perfusion and is necessary for embryonic development and tumor explant growth. HIF-1α is...
Ozawa, Clare R., Banfi, Andrea, Glazer, Nicole L., Thurston, Gavin, Springer, Matthew L., Kraft, Peggy E., ...
Use of long-term constitutive expression of VEGF for therapeutic angiogenesis may be limited by the growth of abnormal blood vessels and hemangiomas. We investigated the relationship between VEGF...
Gale, Nicholas W., Dominguez, Melissa G., Noguera, Irene, Pan, Li, Hughes, Virginia, Valenzuela, David M., ...
Vascular development depends on the highly coordinated actions of a variety of angiogenic regulators, most of which apparently act downstream of vascular endothelial growth factor (VEGF). One...
Complementary actions of VEGF and Angiopoietin-1 on blood vessel growth and leakage*
Vascular endothelial growth factor (VEGF) and Angiopoietins are families of vascular-specific growth factors that regulate blood vessel growth, maturation and function. To learn more about the...
Inai, Tetsuichiro, Mancuso, Michael, Hashizume, Hiroya, Baffert, Fabienne, Haskell, Amy, Baluk, Peter, ...
Angiogenesis inhibitors are receiving increased attention as cancer therapeutics, but little is known of the cellular effects of these inhibitors on tumor vessels. We sought to determine whether two...
Angiopoietin-2 functions as an autocrine protective factor in stressed endothelial cells
Daly, Christopher, Pasnikowski, Elizabeth, Burova, Elena, Wong, Vivian, Aldrich, Thomas H., Griffiths, Jennifer, ...
Angiopoietin (Ang)-2, a context-dependent agonist/antagonist for the vascular-specific Tie2 receptor, is highly expressed by endothelial cells at sites of normal and pathologic angiogenesis. One...
Gale, Nicholas W., Prevo, Remko, Espinosa, Jorge, Ferguson, David J., Dominguez, Melissa G., Yancopoulos, George D., ...
The hyaluronan receptor LYVE-1 is expressed abundantly on the surfaces of lymphatic vessels and lymph node sinus endothelial cells from early development, where it has been suggested to function both...
Openings between Defective Endothelial Cells Explain Tumor Vessel Leakiness
Hashizume, Hiroya, Baluk, Peter, Morikawa, Shunichi, McLean, John W., Thurston, Gavin, Roberge, Sylvie, ...
Leakiness of blood vessels in tumors may contribute to disease progression and is key to certain forms of cancer therapy, but the structural basis of the leakiness is unclear. We sought to determine...
Angiogenesis in Mice with Chronic Airway Inflammation : Strain-Dependent Differences
Thurston, Gavin, Murphy, Thomas J., Baluk, Peter, Lindsey, J. Russell, McDonald, Donald M.
Chronic inflammation is associated with blood vessel proliferation and enlargement and changes in vessel phenotype. We sought to determine whether these changes represent different types of...
Murphy, Thomas J., Thurston, Gavin, Ezaki, Taichi, McDonald, Donald M.
We sought to determine whether the changes in microvascular endothelial cells (EC) caused by a polarized chronic inflammatory stimulus depend on proximity to the stimulus. C3H mice were infected with...
Time Course of Endothelial Cell Proliferation and Microvascular Remodeling in Chronic Inflammation
Ezaki, Taichi, Baluk, Peter, Thurston, Gavin, La Barbara, Allyson, Woo, Carolyn, McDonald, Donald M.
Angiogenesis and vascular remodeling are features of many chronic inflammatory diseases. When diseases evolve slowly, the accompanying changes in the microvasculature would seem to be similarly...
Dominguez, Melissa G., Hughes, Virginia C., Pan, Li, Simmons, Mary, Daly, Christopher, Anderson, Keith, ...
Development of the vascular system depends on the highly coordinated actions of a variety of angiogenic regulators. Several of these regulators are members of the tyrosine kinase superfamily,...
Neurogenic plasma leakage in mouse airways
Baluk, Peter, Thurston, Gavin, Murphy, Thomas J, Bunnett, Nigel W, McDonald, Donald M
This study sought to determine whether neurogenic inflammation occurs in the airways by examining the effects of capsaicin or substance P on microvascular plasma leakage in the trachea and lungs of...
Rudge, John S., Holash, Jocelyn, Hylton, Donna, Russell, Michelle, Jiang, Shelly, Leidich, Raymond, ...
VEGF is the best characterized mediator of tumor angiogenesis. Anti-VEGF agents have recently demonstrated impressive efficacy in human cancer trials, but the optimal dosing of such agents must still...
Shmelkov, Sergey V., Butler, Jason M., Hooper, Andrea T., Hormigo, Adilia, Kushner, Jared, Milde, Till, ...
Colon cancer stem cells are believed to originate from a rare population of putative CD133+ intestinal stem cells. Recent publications suggest that a small subset of colon cancer cells expresses...