Association testing by haplotype-sharing methods applicable to whole-genome analysis (2007)
Nolte, Ilja M, De Vries, André R, Spijker, Geert T, Jansen, Ritsert C, Brinza, Dumitru, Zelikovsky, Alexander, ...
Abstract We propose two new haplotype-sharing methods for identifying disease loci: the haplotype sharing statistic (HSS), which compares length of shared haplotypes between cases and controls, and...
Association testing by haplotype-sharing methods applicable to whole-genome analysis (2007)
Nolte, Ilja M., Vries, André R. De, Spijker, Geert T., Jansen, Ritsert C., Brinza, Dumitru, Zelikovsky, Alexander, ...
We propose two new haplotype-sharing methods for identifying disease loci: the haplotype sharing statistic (HSS), which compares length of shared haplotypes between cases and controls, and the CROSS...
Efficiency Control in Large-Scale Genotyping Using Analysis of Variance (2005)
Spijker, Geert T., Bruinenberg, Marcel, Meerman, Gerard J. Te
The efficiency of the genotyping process is determined by many simultaneous factors. In actual genotyping, a production run is often preceded by small-scale experiments to find optimal conditions. We...
Simulation Studies of Detection of a Complex Disease in a Partially Isolated Population (2001)
Levinson, Douglas F., Kirby, Andrew, Slepner, Stephen, Nolte, Ilja, Spijker, Geert T., Meerman, Gerard Te
Simulation studies were undertaken with POPGEN, a new population simulation program, to explore strategies for detecting loci underlying rare and common disorders in a small population that has been...
Boon, Maartje, Nolte, Ilja M., Bruinenberg, Marcel, Spijker, Geert T., Terpstra, Peter, Raelson, John, ...
Multiple sclerosis (MS) is a complex disease that is partly genetic in origin. Although an association of MS with specific human leukocyte antigen (HLA) types has been known for almost 30 years, the...
Association testing by haplotype-sharing methods applicable to whole-genome analysis
Nolte, Ilja M, De Vries, André R, Spijker, Geert T, Jansen, Ritsert C, Brinza, Dumitru, Zelikovsky, Alexander, ...
We propose two new haplotype-sharing methods for identifying disease loci: the haplotype sharing statistic (HSS), which compares length of shared haplotypes between cases and controls, and the CROSS...