Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease (2008)
Bryan, Kathryn J, Zhu, Xiongwei, Harris, Peggy L, Perry, George, Castellani, Rudy J, Smith, Mark A, ...
Abstract Alzheimer disease (AD) is a chronic neurodegenerative disease that is characterized by progressive memory loss. Pathological markers of AD include neurofibrillary tangles, accumulation of...
The role of metabotropic glutamate receptors in Alzheimer’s disease (2008)
Neu Obiologi E, Hyoung-gon Lee, Xiongwei Zhu, Michael J. O’neill, Gemma Casadesus, ...
Abstract. While glutamatergic transmission is severely altered by early degeneration of cortico-cortical connections and hippocampal projections in Alzheimer’s disease (AD), the role of glutamate...
Thakur, Akanksha, Siedlak, Sandra L, James, Sheronica L, Bonda, David J, Rao, Akanksha, Webber, Kate M, ...
The re-expression of multiple cell cycle markers representing various cell cycle phases in postmitotic pyramidal neurons suggests that neurons in Alzheimer disease (AD) attempt to re-enter the cell...
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease. (2008)
Bryan, Kathryn J, Zhu, Xiongwei, Harris, Peggy L, Perry, George, Castellani, Rudy J, Smith, Mark A, ...
ABSTRACT: Alzheimer disease (AD) is a chronic neurodegenerative disease that is characterized by progressive memory loss. Pathological markers of AD include neurofibrillary tangles, accumulation of...
Wang, Xinglong, Su, Bo, Siedlak, Sandra L., Moreira, Paula I., Fujioka, Hisashi, Wang, Yang, ...
Mitochondrial dysfunction is a prominent feature of Alzheimer disease but the underlying mechanism is unclear. In this study, we investigated the effect of amyloid precursor protein (APP) and amyloid...
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease (2007)
Casadesus, Gemma, Smith, Mark A, Basu, Samar, Hua, Jing, Capobianco, Dae E, Siedlak, Sandra L, ...
Abstract Background Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been...
The contribution of luteinizing hormone to Alzheimer disease pathogenesis. (2007)
Webber, Kate M., Perry, George, Smith, Mark A., Casadesus, Gemma
Several hypotheses have been proposed that attempt to explain the pathogenesis of Alzheimer Disease (AD) including theories involving senile plaque and neurofibrillary tangle formation, increased...
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease. (2007)
Casadesus, Gemma, Smith, Mark A, Basu, Samar, Hua, Jing, Capobianco, Dae E, Siedlak, Sandra L, ...
BACKGROUND: Inflammation and oxidative stress are both involved in the pathogenesis of Alzheimer disease and have been shown to be reciprocally linked. One group of molecules that have been directly...
The contribution of luteinizing hormone to Alzheimer disease pathogenesis. (2007)
Webber, Kate M., Perry, George, Smith, Mark A., Casadesus, Gemma
Several hypotheses have been proposed that attempt to explain the pathogenesis of Alzheimer Disease (AD) including theories involving senile plaque and neurofibrillary tangle formation, increased...
Webber, Kate M, Stocco, Douglas M, Casadesus, Gemma, Bowen, Richard L, Atwood, Craig S, Previll, Laura A, ...
Abstract Background Alzheimer disease (AD) is clinically characterized by progressive memory loss, impairments in behavior, language and visual-spatial skills and ultimately, death. Epidemiological...
Targeting gonadotropins: an alternative option for Alzheimer disease treatment. (2006)
Casadesus, Gemma, Puig, Emma Ramiro, Webber, Kate M., Atwood, Craig S., Escuer, Margarida Castell, Bowen, Richard L., ...
Recent evidence indicates that, alongside oxidative stress, dysregulation of the cell cycle in neurons susceptible to degeneration in Alzheimer disease may play a crucial role in the initiation of...
Webber, Kate M, Stocco, Douglas M, Casadesus, Gemma, Bowen, Richard L, Atwood, Craig S, Previll, Laura A, ...
BACKGROUND: Alzheimer disease (AD) is clinically characterized by progressive memory loss, impairments in behavior, language and visual-spatial skills and ultimately, death. Epidemiological data...
Targeting Gonadotropins: An Alternative Option for Alzheimer Disease Treatment (2006)
Gemma Casadesus, Emma Ramiro Puig, Kate M. Webber, Craig S. Atwood, Margarida Castell Escuer, Richard L. Bowen, ...
Recent evidence indicates that, alongside oxidative stress, dysregulation of the cell cycle in neurons susceptible to degeneration in Alzheimer disease may play a crucial role in the initiation of...
Spatial Learning and Memory Deficits Induced by Exposure to Iron-56-Particle Radiation (2000)
Barbara Shukitt-Hale, Gemma Casadesus, John J. McEwen, Bernard M. Rabin, James A. Joseph
Shukitt-Hale, B., Casadesus, G., McEwen, J. J., Rabin, B. M. and Joseph, J. A. Spatial Learning and Memory Deficits Induced by Exposure to Iron-56-Particle Radiation. It has previously been shown...
Targeting Gonadotropins: An Alternative Option for Alzheimer Disease Treatment
Casadesus, Gemma, Puig, Emma Ramiro, Webber, Kate M., Atwood, Craig S., Escuer, Margarida Castell, Bowen, Richard L., ...
Recent evidence indicates that, alongside oxidative stress, dysregulation of the cell cycle in neurons susceptible to degeneration in Alzheimer disease may play a crucial role in the initiation of...
Webber, Kate M, Stocco, Douglas M, Casadesus, Gemma, Bowen, Richard L, Atwood, Craig S, Previll, Laura A, ...
Targeting Gonadotropins: An Alternative Option for Alzheimer Disease Treatment
Casadesus, Gemma, Puig, Emma Ramiro, Webber, Kate M., Atwood, Craig S., Escuer, Margarida Castell, Bowen, Richard L., ...
Recent evidence indicates that, alongside oxidative stress, dysregulation of the cell cycle in neurons susceptible to degeneration in Alzheimer disease may play a crucial role in the initiation of...
Webber, Kate M, Stocco, Douglas M, Casadesus, Gemma, Bowen, Richard L, Atwood, Craig S, Previll, Laura A, ...
Increased isoprostane and prostaglandin are prominent in neurons in Alzheimer disease
Casadesus, Gemma, Smith, Mark A, Basu, Samar, Hua, Jing, Capobianco, Dae E, Siedlak, Sandra L, ...
The Contribution of Luteinizing Hormone to Alzheimer Disease Pathogenesis
Webber, Kate M., Perry, George, Smith, Mark A., Casadesus, Gemma
Several hypotheses have been proposed that attempt to explain the pathogenesis of Alzheimer Disease (AD) including theories involving senile plaque and neurofibrillary tangle formation, increased...
Thakur, Akanksha, Siedlak, Sandra L, James, Sheronica L, Bonda, David J, Rao, Akanksha, Webber, Kate M, ...
The re-expression of multiple cell cycle markers representing various cell cycle phases in postmitotic pyramidal neurons suggests that neurons in Alzheimer disease (AD) attempt to re-enter the cell...
Expression of CD74 is increased in neurofibrillary tangles in Alzheimer's disease
Bryan, Kathryn J, Zhu, Xiongwei, Harris, Peggy L, Perry, George, Castellani, Rudy J, Smith, Mark A, ...
Alzheimer disease (AD) is a chronic neurodegenerative disease that is characterized by progressive memory loss. Pathological markers of AD include neurofibrillary tangles, accumulation of amyloid-β...
Wang, Xinglong, Su, Bo, Siedlak, Sandra L., Moreira, Paula I., Fujioka, Hisashi, Wang, Yang, ...
Mitochondrial dysfunction is a prominent feature of Alzheimer disease but the underlying mechanism is unclear. In this study, we investigated the effect of amyloid precursor protein (APP) and amyloid...
The Neuronal Expression of MYC Causes a Neurodegenerative Phenotype in a Novel Transgenic Mouse
Lee, Hyoung-gon, Casadesus, Gemma, Nunomura, Akihiko, Zhu, Xiongwei, Castellani, Rudy J., Richardson, Sandy L., ...
Many different proteins associated with the cell cycle, including cyclins, cyclin-dependent kinases, and proto-oncogenes such as c-MYC (MYC), are increased in degenerating neurons. Consequently, an...