Gen Tamiya

Whole Genome Association Study of Rheumatoid Arthritis Using 27,039 Microsatellites (2005)

Gen Tamiya, Minori Shinya, Tadashi Imanishi, Tomoki Ikuta, Koichi Okamoto, Koh Furugaki, ...

© The Author 2005. Published by Oxford University Press. All rights reserved The online version of this article has been published under an open access model. Users are entitled to use, reproduce,...

Whole genome association study of rheumatoid arthritis using 27,039 microsatellites (2005)

Tamiya, Gen, Shinya, Minori, Imanishi, Tadashi, Ikuta, Tomoki, Makino, Satoshi, Okamoto, Koichi, ...

A major goal of current human genome-wide studies is to identify the genetic basis of complex disorders. However, the availability of an unbiased, reliable, cost efficient and comprehensive...

Whole genome association study of rheumatoid arthritis using 27 039 microsatellites (2005)

Tamiya, Gen, Shinya, Minori, Imanishi, Tadashi, Ikuta, Tomoki, Makino, Satoshi, Okamoto, Koichi, ...

A major goal of current human genome-wide studies is to identify the genetic basis of complex disorders. However, the availability of an unbiased, reliable, cost efficient and comprehensive...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

An international team has systematically validated and annotated just over 21,000 human genes using full-length cDNA, thereby providing a valuable new resource for the human genetics community.

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones (2004)

Tadashi Imanishi, Takeshi Itoh, Yutaka Suzuki, Claire O'Donovan, Satoshi Fukuchi, Kanako O. Koyanagi, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

Novel algorithm for automated genotyping of microsatellites (2004)

Matsumoto, Toshiko, Yukawa, Wataru, Nozaki, Yasuyuki, Nakashige, Ryo, Shinya, Minori, Makino, Satoshi, ...

Microsatellites or short tandem repeats (STRs) are abundant in the human genome with easily assayed polymorphisms, providing powerful genetic tools for mapping both Mendelian and complex traits....

Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region

Shiina, Takashi, Tamiya, Gen, Oka, Akira, Takishima, Nobusada, Yamagata, Tetsushi, Kikkawa, Eri, ...

The intensely studied MHC has become the paradigm for understanding the architectural evolution of vertebrate multigene families. The 4-Mb human MHC (also known as the HLA complex) encodes genes...

Association of a Determinant on Mouse Chromosome 18 with Experimental Severe Plasmodium berghei Malaria

Nagayasu, Eiji, Nagakura, Koichi, Akaki, Mayumi, Tamiya, Gen, Makino, Satoshi, Nakano, Yamaji, ...

Experimental severe malaria (ESM; also known as experimental cerebral malaria) is an acute lethal syndrome caused by infection with Plasmodium berghei ANKA and associated with coma and other...

Genomic Anatomy of a Premier Major Histocompatibility Complex Paralogous Region on Chromosome 1q21–q22

Shiina, Takashi, Ando, Asako, Suto, Yumiko, Kasai, Fumio, Shigenari, Atsuko, Takishima, Nobusada, ...

Human chromosomes 1q21–q25, 6p21.3–22.2, 9q33–q34, and 19p13.1–p13.4 carry clusters of paralogous loci, to date best defined by the flagship 6p MHC region. They have presumably been created...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

Novel algorithm for automated genotyping of microsatellites

Matsumoto, Toshiko, Yukawa, Wataru, Nozaki, Yasuyuki, Nakashige, Ryo, Shinya, Minori, Makino, Satoshi, ...

Microsatellites or short tandem repeats (STRs) are abundant in the human genome with easily assayed polymorphisms, providing powerful genetic tools for mapping both Mendelian and complex traits....

Fine Localization of a Major Disease-Susceptibility Locus for Diffuse Panbronchiolitis

Keicho, Naoto, Ohashi, Jun, Tamiya, Gen, Nakata, Koichiro, Taguchi, Yoshio, Azuma, Arata, ...

Diffuse panbronchiolitis affecting East Asians is strongly associated with the class I human leukocyte antigen (HLA) alleles. Recent observations suggest that a major disease-susceptibility gene may...

Molecular dynamics of MHC genesis unraveled by sequence analysis of the 1,796,938-bp HLA class I region

Shiina, Takashi, Tamiya, Gen, Oka, Akira, Takishima, Nobusada, Yamagata, Tetsushi, Kikkawa, Eri, ...

The intensely studied MHC has become the paradigm for understanding the architectural evolution of vertebrate multigene families. The 4-Mb human MHC (also known as the HLA complex) encodes genes...

Association of a Determinant on Mouse Chromosome 18 with Experimental Severe Plasmodium berghei Malaria

Nagayasu, Eiji, Nagakura, Koichi, Akaki, Mayumi, Tamiya, Gen, Makino, Satoshi, Nakano, Yamaji, ...

Experimental severe malaria (ESM; also known as experimental cerebral malaria) is an acute lethal syndrome caused by infection with Plasmodium berghei ANKA and associated with coma and other...

Genomic Anatomy of a Premier Major Histocompatibility Complex Paralogous Region on Chromosome 1q21–q22

Shiina, Takashi, Ando, Asako, Suto, Yumiko, Kasai, Fumio, Shigenari, Atsuko, Takishima, Nobusada, ...

Human chromosomes 1q21–q25, 6p21.3–22.2, 9q33–q34, and 19p13.1–p13.4 carry clusters of paralogous loci, to date best defined by the flagship 6p MHC region. They have presumably been created...

Identification of IκBL as the Second Major Histocompatibility Complex–Linked Susceptibility Locus for Rheumatoid Arthritis

Okamoto, Koichi, Makino, Satoshi, Yoshikawa, Yoko, Takaki, Asumi, Nagatsuka, Yumie, Ota, Masao, ...

Rheumatoid arthritis (RA) is a chronic inflammatory joint disease with a complex etiology in which environmental factors within a genetically susceptible host maneuver the innate and adaptive arms of...

Integrative Annotation of 21,037 Human Genes Validated by Full-Length cDNA Clones

Imanishi, Tadashi, Itoh, Takeshi, Suzuki, Yutaka, O'Donovan, Claire, Fukuchi, Satoshi, Koyanagi, Kanako O, ...

The human genome sequence defines our inherent biological potential; the realization of the biology encoded therein requires knowledge of the function of each gene. Currently, our knowledge in this...

Novel algorithm for automated genotyping of microsatellites

Matsumoto, Toshiko, Yukawa, Wataru, Nozaki, Yasuyuki, Nakashige, Ryo, Shinya, Minori, Makino, Satoshi, ...

Microsatellites or short tandem repeats (STRs) are abundant in the human genome with easily assayed polymorphisms, providing powerful genetic tools for mapping both Mendelian and complex traits....

Natural Selection and Population History in the Human Angiotensinogen Gene (AGT): 736 Complete AGT Sequences in Chromosomes from Around the World

Nakajima, Toshiaki, Wooding, Stephen, Sakagami, Takuro, Emi, Mitsuru, Tokunaga, Katsushi, Tamiya, Gen, ...

Several lines of evidence suggest that patterns of genetic variability in the human angiotensinogen gene (AGT) contribute to phenotypic variability in human hypertension. The A(−6) promoter variant...

Fine Localization of a Major Disease-Susceptibility Locus for Diffuse Panbronchiolitis

Keicho, Naoto, Ohashi, Jun, Tamiya, Gen, Nakata, Koichiro, Taguchi, Yoshio, Azuma, Arata, ...

Diffuse panbronchiolitis affecting East Asians is strongly associated with the class I human leukocyte antigen (HLA) alleles. Recent observations suggest that a major disease-susceptibility gene may...

Genomewide Association Analysis of Human Narcolepsy and a New Resistance Gene

Kawashima, Minae, Tamiya, Gen, Oka, Akira, Hohjoh, Hirohiko, Juji, Takeo, Ebisawa, Takashi, ...

Human narcolepsy is a hypersomnia that is affected by multiple genetic and environmental factors. One genetic factor strongly associated with narcolepsy is the HLA-DRB1*1501-DQB1*0602 haplotype in...

Reduced Neuron-Specific Expression of the TAF1 Gene Is Associated with X-Linked Dystonia-Parkinsonism

Makino, Satoshi, Kaji, Ryuji, Ando, Satoshi, Tomizawa, Maiko, Yasuno, Katsuhito, Goto, Satoshi, ...

X-linked dystonia-parkinsonism (XDP) is a movement disorder endemic to the Philippines. The disease locus, DYT3, has been mapped to Xq13.1. In a search for the causative gene, we performed genomic...

Genetic Analysis of Craniofacial Traits in the Medaka

Kimura, Tetsuaki, Shimada, Atsuko, Sakai, Noriyoshi, Mitani, Hiroshi, Naruse, Kiyoshi, Takeda, Hiroyuki, ...

Family and twin studies suggest that a substantial genetic component underlies individual differences in craniofacial morphology. In the current study, we quantified 444 craniofacial traits in 100...