Weber, Frank, Shen, Lei, Fukino, Koichi, Patocs, Attila, Mutter, George L., Caldes, Trinidad, ...
We have shown that the tumor microenvironment of sporadic breast cancer is diverse in genetic alterations and contributes to the cancer phenotype. The dynamic morphology of the mammary gland might be...
Baak, Jan P, Mutter, George L, Robboy, Stanley, Van Diest, Paul J, Uyterlinde, Anne M, Orbo, Anne, ...
BACKGROUND: The objective of this study was to compare the accuracy of disease progression prediction of the molecular genetics and morphometry-based Endometrial Intraepithelial Neoplasia (EIN) and...
Mutter, George L, Zahrieh, David, Liu, Chunmei, Neuberg, Donna, Finkelstein, David, Baker, Heather E, ...
Abstract Background Primary human tissues are an invaluable widely used tool for discovery of gene expression patterns which characterize disease states. Tissue processing methods remain...
Altered PTEN Expression as a Diagnostic Marker for the Earliest Endometrial Precancers (2000)
Mutter, George L., Lin, Ming-Chieh, Fitzgerald, Jeffrey T., Kum, Jennifer B., Baak, Jan P. A., Lees, Jacqueline A., ...
Background: PTEN tumor suppressor gene mutations are the most frequent genetic lesions in endometrial adenocarcinomas of the endometrioid subtype. Testing the hypothesis that altered PTEN function...
Testis-specific expression of the human MYCL2 gene (1991)
Robertson, Nahid G., Pomponio, Robert J., Mutter, George L., Morton, Cynthia C.
We have characterized the expression of MYCL2, an intronless X-linked gene related to MYCL1. RNase protection analysis of a panel of human normal and tumor tissues has revealed that MYCL2 is...
Ford, Heide L., Kabingu, Edith N., Bump, Edward A., Mutter, George L., Pardee, Arthur B.
While conducting a search for cell cycle-regulated genes in human mammary carcinoma cells, we identified HSIX1, a recently discovered member of a new homeobox gene subfamily. HSIX1 expression was...
Comparison of frozen and RNALater solid tissue storage methods for use in RNA expression microarrays
Mutter, George L, Zahrieh, David, Liu, Chunmei, Neuberg, Donna, Finkelstein, David, Baker, Heather E, ...
Weber, Frank, Shen, Lei, Fukino, Koichi, Patocs, Attila, Mutter, George L., Caldes, Trinidad, ...
We have shown that the tumor microenvironment of sporadic breast cancer is diverse in genetic alterations and contributes to the cancer phenotype. The dynamic morphology of the mammary gland might be...
Ford, Heide L., Kabingu, Edith N., Bump, Edward A., Mutter, George L., Pardee, Arthur B.
While conducting a search for cell cycle-regulated genes in human mammary carcinoma cells, we identified HSIX1, a recently discovered member of a new homeobox gene subfamily. HSIX1 expression was...
Comparison of frozen and RNALater solid tissue storage methods for use in RNA expression microarrays
Mutter, George L, Zahrieh, David, Liu, Chunmei, Neuberg, Donna, Finkelstein, David, Baker, Heather E, ...
Weber, Frank, Shen, Lei, Fukino, Koichi, Patocs, Attila, Mutter, George L., Caldes, Trinidad, ...
We have shown that the tumor microenvironment of sporadic breast cancer is diverse in genetic alterations and contributes to the cancer phenotype. The dynamic morphology of the mammary gland might be...
Gimm, Oliver, Perren, Aurel, Weng, Liang-Ping, Marsh, Debbie J., Yeh, Jen Jen, Ziebold, Ulrike, ...
Germline mutations in PTEN (MMAC1/TEP1) are found in patients with Cowden syndrome, a familial cancer syndrome which is characterized by a high risk of breast and thyroid neoplasia. Although somatic...
Allelic Loss in Human Papillomavirus-Positive and -Negative Vulvar Squamous Cell Carcinomas
Pinto, Alvaro P., Lin, Ming-Chieh, Mutter, George L., Sun, Deqin, Villa, Luisa Lina, Crum, Christopher P.
Vulvar squamous cell carcinoma (VSCC) is a biologically and morphologically diverse disease, consisting of human papillomavirus (HPV)-positive and -negative tumors that differ in their morphological...
hMLH1 Promoter Hypermethylation Is an Early Event in Human Endometrial Tumorigenesis
Esteller, Manel, Catasus, Lluis, Matias-Guiu, Xavier, Mutter, George L., Prat, Jaime, Baylin, Steve B., ...
It has recently been suggested that silencing of the hMLH1 gene by promoter hypermethylation is the mechanism underlying the presence of the microsatellite instability (MSI) phenotype in sporadic...
Perren, Aurel, Weng, Liang-Ping, Boag, Alexander H., Ziebold, Ulricke, Thakore, Kosha, Dahia, Patricia L. M., ...
Germline mutations in PTEN, encoding a dual-specificity phosphatase on 10q23.3, cause Cowden syndrome (CS), which is characterized by a high risk of breast and thyroid cancers. Loss of heterozygosity...
Ince, Tan A., Cviko, Aida P., Quade, Bradley J., Yang, Annie, McKeon, Frank D., Mutter, George L., ...
p63 is a p53 homologue required for cutaneous development that is expressed in immature squamous epithelium and reserve cells of the cervix. Humans with p63 mutations exhibit defects in limb,...