Gerald M Rosen

Neuronal nitric oxide synthase-induced S-nitrosylation of H-Ras inhibits calcium ionophore-mediated extracellular-signal-regulated kinase activity

Raines, Kimberly W., Cao, Guan-Liang, Lee, Eun Kyoung, Rosen, Gerald M., Shapiro, Paul

nNOS (neuronal nitric oxide synthase) is a constitutively expressed enzyme responsible for the production of NO• from L-arginine and O2. NO• acts as both an intra- and an inter-cellular messenger...