Gish, Gerald, McGlone, Maria L., Pawson, Tony, Adams, Joseph A.
The gene coding for the tyrosine protein kinase domain of v-fps was subcloned into a plasmid vector expressing glutathione-S-transferase (GST). This new vector expresses a fusion protein in...
Nakamaye, Kay L., Gish, Gerald, Eckstein, Fritz, Vosberg, Hans-Peter
The direct sequencing of DNA generated by the polynucleotide chain reaction, via the incorporation of phosphorothioate nucleotides and followed by treatment with an alkylating reagent that cleaves...
Winberg, Gösta, Matskova, Liudmila, Chen, Fu, Plant, Pamela, Rotin, Daniela, Gish, Gerald, ...
The latent membrane protein (LMP) 2A of Epstein-Barr virus (EBV) is implicated in the maintenance of viral latency and appears to function in part by inhibiting B-cell receptor (BCR) signaling. The...
Donaldson, Logan W., Gish, Gerald, Pawson, Tony, Kay, Lewis E., Forman-Kay, Julie D.
On phosphorylation of Y221 by Abelson (Abl) kinase, the Crk-II adapter protein undergoes an intramolecular reorganization initiated by the binding of its own Src homology 2 (SH2) domain to the pY221...
The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis
Bakal, Christopher J., Finan, Dina, LaRose, José, Wells, Clark D., Gish, Gerald, Kulkarni, Sarang, ...
Rho GTPases regulate reorganization of actin and microtubule cytoskeletal structures during both interphase and mitosis. The timing and subcellular compartment in which Rho GTPases are activated is...
WW Domains Provide a Platform for the Assembly of Multiprotein Networks†
Ingham, Robert J., Colwill, Karen, Howard, Caley, Dettwiler, Sabine, Lim, Caesar S. H., Yu, Joanna, ...
WW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs and phosphorylated serine/threonine-proline sites. To pursue the functional...
Winberg, Gösta, Matskova, Liudmila, Chen, Fu, Plant, Pamela, Rotin, Daniela, Gish, Gerald, ...
The latent membrane protein (LMP) 2A of Epstein-Barr virus (EBV) is implicated in the maintenance of viral latency and appears to function in part by inhibiting B-cell receptor (BCR) signaling. The...
Donaldson, Logan W., Gish, Gerald, Pawson, Tony, Kay, Lewis E., Forman-Kay, Julie D.
On phosphorylation of Y221 by Abelson (Abl) kinase, the Crk-II adapter protein undergoes an intramolecular reorganization initiated by the binding of its own Src homology 2 (SH2) domain to the pY221...
The Rho GTP exchange factor Lfc promotes spindle assembly in early mitosis
Bakal, Christopher J., Finan, Dina, LaRose, José, Wells, Clark D., Gish, Gerald, Kulkarni, Sarang, ...
Rho GTPases regulate reorganization of actin and microtubule cytoskeletal structures during both interphase and mitosis. The timing and subcellular compartment in which Rho GTPases are activated is...
WW Domains Provide a Platform for the Assembly of Multiprotein Networks†
Ingham, Robert J., Colwill, Karen, Howard, Caley, Dettwiler, Sabine, Lim, Caesar S. H., Yu, Joanna, ...
WW domains are protein modules that mediate protein-protein interactions through recognition of proline-rich peptide motifs and phosphorylated serine/threonine-proline sites. To pursue the functional...
Role of P120 Ras-Gap in Directed Cell Movement
Kulkarni, Sarang V., Gish, Gerald, Van Der Geer, Peter, Henkemeyer, Mark, Pawson, Tony
We have used cell lines deficient in p120 Ras GTPase activating protein (Ras-GAP) to investigate the roles of Ras-GAP and the associated p190 Rho-GAP (p190) in cell polarity and cell migration. Cell...