Human Y-79 Retinoblastoma Cells Exhibit Specific Insulin Receptors, (2002)
Saviolakis,George A., Kyritsis,Athanassios P., Chader,Gerald J.
The presence of insulin receptors was in investigated in human Y-79 retinobastoma cells grown in suspension culture. The binding of (125I) insulin to these cells was time, temperature, and pH...
Tombran-Tink, Joyce, Pawar, Hemant, Swaroop, Anand, Rodriguez, Ignacio, Chader, Gerald J.
The gene for pigment epithelium-derived factor (PEDF) was localized to chromosome 17 by the analysis of three independent somatic cell hybrid panels. Fluorescence in situ hybridization shows a...
Albini, Adriana, Toffenetti, Judith, Zhu, Zhen, Chader, Gerald J., Noonan, Douglas M.
The interphotoreceptor retinoid-binding protein (IRBP) is limited in expression to retinal photoreceptor cells and a subset of pinealocytes. We have obtained a genomic clone containing the entire...
An estrogen receptor repressor induces cataract formation in transgenic mice
Davis, Vicki L., Chan, Chi-Chao, Schoen, Timothy J., Couse, John F., Chader, Gerald J., Korach, Kenneth S.
Despite the high prevalence of age-related cataracts, there are currently no known therapies to delay or prevent their occurrence. Studies in humans and rodent models suggest that estrogen may...
Uptake of oestradiol by the rabbit hypothalamus. Specificity of binding by nuclei in vitro
Chader, Gerald J., Villee, Claude A.
The binding of [6,7-3H]oestradiol-17β to subcellular fractions of the hypothalamus and the cerebellum of the rabbit was studied in vitro. Uptake of steroid was higher in hypothalamic nuclei than in...
An estrogen receptor repressor induces cataract formation in transgenic mice
Davis, Vicki L., Chan, Chi-Chao, Schoen, Timothy J., Couse, John F., Chader, Gerald J., Korach, Kenneth S.
Despite the high prevalence of age-related cataracts, there are currently no known therapies to delay or prevent their occurrence. Studies in humans and rodent models suggest that estrogen may...
Uptake of oestradiol by the rabbit hypothalamus. Specificity of binding by nuclei in vitro
Chader, Gerald J., Villee, Claude A.
The binding of [6,7-3H]oestradiol-17β to subcellular fractions of the hypothalamus and the cerebellum of the rabbit was studied in vitro. Uptake of steroid was higher in hypothalamic nuclei than in...