Gene expression profiling in livers of mice after acute inhibition of β-oxidation (2007)
Bloks, Vincent W., Grefhorst, Aldo, Hoekstra, Jildou, Gerding, Albert, Kooi, Krista, ...
Inborn errors of mitochondrial β-oxidation cause ectopic fat accumulation, particularly in the liver. Fatty liver is associated with insulin resistance and predisposes to hepatic fibrosis. The...
Foerster, John, Nolte, Ilja, Junge, Judith, Bruinenberg, Marcel, Schweiger, Susann, Spaar, Katja, ...
The psoriasis susceptibility locus 1 (PSORS1) mutation is assumed to reside within a region around human leukocyte antigen-C spanning 250 kb, termed risk haplotype (RH) 1/2. By re-analyzing a...
Evaluation of the IRF-2 Gene as a Candidate for PSORS3 (2004)
Foerster, John, Nolte, Ilja, Schweiger, Susann, Ehlert, Claudia, Bruinenberg, Marcel, Spaar, Katja, ...
Type 1 interferon can trigger flares of psoriasis. Hypersensitivity to type 1 interferon signaling causes a psoriasis-like skin disease in mice deficient for the transcription factor interferon...
Fischer, Christine, Beckmann, Lars, Majoram, Paul, Meerman, Gerard Te, Chang-Claude, Jenny
Haplotype sharing analysis was used to investigate the association of affection status with single nucleotide polymorphism (SNP) haplotypes within candidate gene 1 in one sample each from the...
Simulation Studies of Detection of a Complex Disease in a Partially Isolated Population (2001)
Levinson, Douglas F., Kirby, Andrew, Slepner, Stephen, Nolte, Ilja, Spijker, Geert T., Meerman, Gerard Te
Simulation studies were undertaken with POPGEN, a new population simulation program, to explore strategies for detecting loci underlying rare and common disorders in a small population that has been...
Maciejko, Dorota, Bal, Jerzy, Mazurczak, Tadeusz, Meerman, Gerard Te, Buys, Charles, Oostra, Ben, ...
We analyzed DNA from 34 Polish and 63 Dutch cystic fibrosis (CF) patients and their families using the polymorphic markers XV2c and KM19, which are in linkage disequilibrium with the CF mutation....
Rapid Screening for ΔF508 Deletion in Cystic Fibrosis (1989)
Scheffer, Hans, Verlind, Edwin, Penninga, Dirk, Meerman, Gerard Te, Kate, Leo Ten, Buys, Charles
Chromosomal Changes in Human Primary Testicular Nonseminomatous Germ Cell Tumors (1989)
Jong, Bauke De, Oosterhuis, J. Wolter, Seruca, Raquel, Idenburg, Vera J.S., Dam, Anke, ...
A cytogenetic analysis of 14 primary testicular nonseminomatous germ cell tumors has been carried out after short term tissue culture. The modal chromosome numbers ranged from 53 to 113, in agreement...