Gerben Ferwerda

NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis (2005)

Gerben Ferwerda, Stephen E. Girardin, Bart-Jan Kullberg, Lionel Le Bourhis, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. (2005)

Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. (2005)

Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. (2005)

Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. (2005)

Ferwerda, Gerben, Girardin, Stephen, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk, Langenberg, Dennis, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis

Ferwerda, Gerben, Girardin, Stephen E, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk J., Langenberg, Dennis M. L, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1β and IL-6 production through a caspase 1-dependent mechanism

Netea, Mihai G., Azam, Tania, Ferwerda, Gerben, Girardin, Stephen E., Walsh, Mark, Park, Jong-Sung, ...

The activation of innate immunity requires the amplification of signals induced by pattern-recognition receptors for bacterial products. We have investigated the role of the newly described cytokine...

Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

Netea, Mihai G., Gow, Neil A.R., Munro, Carol A., Bates, Steven, Collins, Claire, Ferwerda, Gerben, ...

The fungal pathogen Candida albicans has a multilayered cell wall composed of an outer layer of proteins glycosylated with N- or O-linked mannosyl residues and an inner skeletal layer of β-glucans...

IL-32 synergizes with nucleotide oligomerization domain (NOD) 1 and NOD2 ligands for IL-1β and IL-6 production through a caspase 1-dependent mechanism

Netea, Mihai G., Azam, Tania, Ferwerda, Gerben, Girardin, Stephen E., Walsh, Mark, Park, Jong-Sung, ...

The activation of innate immunity requires the amplification of signals induced by pattern-recognition receptors for bacterial products. We have investigated the role of the newly described cytokine...

NOD2 and Toll-Like Receptors Are Nonredundant Recognition Systems of Mycobacterium tuberculosis

Ferwerda, Gerben, Girardin, Stephen E, Kullberg, Bart-Jan, Le Bourhis, Lionel, De Jong, Dirk J., Langenberg, Dennis M. L, ...

Infection with Mycobacterium tuberculosis is one of the leading causes of death worldwide. Recognition of M. tuberculosis by pattern recognition receptors is crucial for activation of both innate and...

Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors

Netea, Mihai G., Gow, Neil A.R., Munro, Carol A., Bates, Steven, Collins, Claire, Ferwerda, Gerben, ...

The fungal pathogen Candida albicans has a multilayered cell wall composed of an outer layer of proteins glycosylated with N- or O-linked mannosyl residues and an inner skeletal layer of β-glucans...

Differential function of the NACHT-LRR (NLR) members Nod1 and Nod2 in arthritis

Joosten, Leo A. B., Heinhuis, Bas, Abdollahi-Roodsaz, Shahla, Ferwerda, Gerben, LeBourhis, Lionel, Philpott, Dana J., ...

The pathogenesis of chronic joint inflammation remains unclear, although the involvement of pathogen recognition receptors has been suggested recently. In the present article, we describe the role of...

Crohn's disease patients homozygous for the 3020insC NOD2 mutation have a defective NOD2/TLR4 cross-tolerance to intestinal stimuli

Kullberg, Bart Jan, Ferwerda, Gerben, De Jong, Dirk J, Drenth, Joost P H, Joosten, Leo A B, ...

Mutations in nucleotide-binding oligomerization domain-2 (NOD2), leading to defective recognition of bacterial peptidoglycans, are associated with Crohn’s disease. The underlying mechanism that...

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors

Dennehy, Kevin M, Ferwerda, Gerben, Faro-Trindade, Inês, Pyż, Elwira, Willment, Janet A, Taylor, Philip R, ...

Recognition of microbial components by germ-line encoded pattern recognition receptors (PRR) initiates immune responses to infectious agents. We and others have proposed that pairs or sets of PRR...