In vitro heterogeneity of osteogenic cell populations at various equine skeletal sites (2006)
McDuffee, LA, Anderson, GI, Wright, GM, Ryan, DA
Bone cell cultures were evaluated to determine if osteogenic cell populations at different skeletal sites in the horse are heterogeneous. Osteogenic cells were isolated from cortical and cancellous...
McLeod, K, Anderson, GI, Dutta, NK, Smart, RS, Voelcker, NH, Sekel, R, ...
Premature bone resorption and remodeling by osteoclasts can limit the longevity of implant fixation and recovery time. Orally administered bisphosphonates (BPs) have been used to inhibit osteoclast...
McLeod, K, Kumar, S, Smart, RSC, Dutta, N, Voelcker, NH, Anderson, GI, ...
This paper reports the use of X-ray photoelectron spectroscopy (XPS) to investigate bisphosphonate (BP) adsorption onto plasma sprayed hydroxyapatite (HA) coatings commonly used for orthopaedic...
Mechanical loading modulates glutamate receptor subunit expression in bone (2005)
Szczesniak, AM, Gilbert, RW, Mukhida, M, Anderson, GI
The cellular mechanisms coupling mechanical loading with bone remodeling remain unclear. In the CNS, the excitatory amino acid glutamate (Glu) serves as a potent neurotransmitter exerting its effects...
Wear-particle-induced osteoclast osteolysis: The role of particulates and mechanical strain (2004)
MacQuarrie, RA, Chen, YF, Coles, C, Anderson, GI
Periprosthetic osteolysis involves osteoclast activation by wear particulates and their exposure to mechanical perturbation through exposure to shear forces generated by periprosthetic fluid as well...
The effect of Gu-Sui-Bu (Drynaria fortunei) on bone cell activity (2004)
Sun, JS, Theriault, BL, Anderson, GI
We investigated the effects of Gu-Sui-Bu using in vitro bone cell cultures. Primary rabbit and mouse marrow cells were cultured with or without five different concentrations of Gu-Sui-Bu extract....
Objective-To compare the osteogenic potential of cancellous bone of conventional graft sites with that of one nonconventional site (fourth coccygeal vertebra) and to investigate the tibial periosteum...
Taylor, JC, Cuff, SE, Leger, JPL, Morra, A, Anderson, GI
Purpose: This observational study examined the resorptive behavior of normal neonatal rabbit osteoclasts grown on slices of bovine cortical bone as compared to samples of commercially available bone...
Anderson, GI, Orlando, K, Waddell, JP
Objective-To establish whether hydroxyapatite (HA) coatings applied to metal total-hip-replacement components increased synovitis in the coxofemoral joint of dogs. Study Design-An in vivo research...
Anderson, GI, MacQuarrie, R, Osinga, C, Chen, YF, Langman, M, Gilbert, R
Aseptic loosening remains the major problem facing arthroplasty longevity with particulates from component materials touted as the cause of periprosthetic osteolysis. Proposed mechanisms in aseptic...
Plasminogen activator system in osteoclasts (1997)
Yang, JN, Allan, EH, Anderson, GI, Martin, TJ, Minkin, C
To determine which genes of the plasminogen activator (PA) system were expressed in osteoclasts, RNA extracted from microisolated mouse osteoclasts was used as template for reverse transcribed...
Mechanical loading modulates glutamate receptor subunit expression in bone
Szczesniak, AM, Gilbert, RW, Mukhida, M, Anderson, GI
The cellular mechanisms coupling mechanical loading with bone remodeling remain unclear. In the CNS, the excitatory amino acid glutamate (Glu) serves as a potent neurotransmitter exerting its effects...
Plasminogen activator system in osteoclasts
Yang, JN, Allan, EH, Anderson, GI, Martin, TJ, Minkin, C
To determine which genes of the plasminogen activator (PA) system were expressed in osteoclasts, RNA extracted from microisolated mouse osteoclasts was used as template for reverse transcribed...