Giorgio Valle

Information technologies incentivizing scholastic fruition (2009)

KAZANCIGIL, MUSTAFA ASIM, VALLE, GIORGIO, FOLGIERI, RAFFAELLA

Information technologies incentivizing scholastic fruition / F. Epifania, G. Valle, R. Folgieri, M. A. Kazancigil. - In: Proceedings of Society for Information Technology and Teacher Education...

Muscle Research and Gene Ontology: New standards for improved data integration (2009)

Feltrin, Erika, Campanaro, Stefano, Diehl, Alexander D, Ehler, Elisabeth, Faulkner, Georgine, Fordham, Jennifer, ...

Abstract Background The Gene Ontology Project provides structured controlled vocabularies for molecular biology that can be used for the functional annotation of genes and gene products. In a...

Information technologies incentivizing scholastic fruition (2009)

KAZANCIGIL, MUSTAFA ASIM, VALLE, GIORGIO, FOLGIERI, RAFFAELLA

Information technologies incentivizing scholastic fruition / F. Epifania, G. Valle, R. Folgieri, M.A. Kazancigil. - In: Proceedings of Society for Information Technology and Teacher Education...

UN ESPERIMENTO DI APPRENDIMENTO COLLETTIVO, ATTRAVERSO L’USO DI STRUMENTI WEB 2.0, PRESSO L’UNIVERSITA’ STATALE DI MILANO. (2009)

VALLE, GIORGIO, FOLGIERI, RAFFAELLA, A. Andronico, L. Colazzo

UN ESPERIMENTO DI APPRENDIMENTO COLLETTIVO, ATTRAVERSO L’USO DI STRUMENTI WEB 2.0, PRESSO L’UNIVERSITA’ STATALE DI MILANO. / R. Folgieri, F. Epifania, G. Valle. - In: Didamatica 2009 -...

PASS: a program to align short sequences (2009)

Campagna, Davide, Albiero, Alessandro, Bilardi, Alessandra, Caniato, Elisa, Forcato, Claudio, Manavski, Svetlin, ...

Summary: Standard DNA alignment programs are inadequate to manage the data produced by new generation DNA sequencers. To answer this problem, we developed PASS with the objective of improving...

A snapshot of the emerging tomato genome sequence (2009)

Mueller, Lukas, Klein Lankhorst, René, Tanksley, Steven D., Giovannoni, James J., White, Ruth, Vrebalov, Julia, ...

The genome of tomato (Solanum lycopersicum L.) is being sequenced by an international consortium of 10 countries (Korea, China, the United Kingdom, India, the Netherlands, France, Japan, Spain,...

Annotating genomes with massive-scale RNA sequencing (2008)

Denoeud, France, Aury, Jean-Marc, Da Silva, Corinne, Noel, Benjamin, Rogier, Odile, Delledonne, Massimo, ...

Abstract Next generation technologies enable massive-scale cDNA sequencing (so-called RNA-Seq). Mainly because of the difficulty of aligning short reads on exon-exon junctions, no attempts have been...

Protein evolution in deep sea bacteria: an analysis of amino acids substitution rates (2008)

Campanaro, Stefano, Treu, Laura, Valle, Giorgio

Abstract Background Abyssal microorganisms have evolved particular features that enable them to grow in their extreme habitat. Genes belonging to specific functional categories are known to be...

FOX (FOld eXtractor): A novel protein fold recognition method using iterative PSI-BLAST searches and structural alignments (2008)

Paolo Fontana, Riccardo Velasco, Giorgio Valle

We present a novel fold recognition method based on the combination of detailed sequence searches and structural information. Presently the protocol implements two different approaches to assign the...

CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment (2008)

Manavski, Svetlin A, Valle, Giorgio

Abstract Background Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more than 25...

An Interactive VideoJournal to complement Learning & Training (2008)

VALLE, GIORGIO, G. Valle, F. Epifania, T. Bastiaens, S. Caeliner

An Interactive VideoJournal to complement Learning & Training / G. Valle, F. Epifania. - In: Proceedings of World Conference on Educational Multimedia, Hypermedia and Telecommunications 2008 ; T....

BioMed Central (2008)

Bmc Bioinformatics, Svetlin A Manavski, Giorgio Valle

CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment

CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment (2008)

Manavski, Svetlin A, Valle, Giorgio

Background Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more than 25 years. It is...

Article type (2008)

Erika Feltrin, Stefano Campanaro, Alexander D. Diehl, Elisabeth Ehler, Georgine Faulkner, Jennifer Fordham, ...

PDF corresponds to the article as it appeared upon acceptance. Fully formatted PDF and full text (HTML) versions will be made available soon. Muscle Research and Gene Ontology: New standards for...

BMC Bioinformatics BioMed Central Open Access BMC 32002, (2007)

Rehannah Ha Borup, Yi-wen Chen, Tanya M Teslovich, Gerolamo Lanfranchi, Giorgio Valle, Eric P Hoffman, ...

Research article Development and production of an oligonucleotide MuscleChip: use for validation of ambiguous ESTs

TRAIT: A KNOWLEDGEBASE TO RETRIEVE ANNOTATED AND DIFFERENTIALLY EXPRESSED TRANSCRIPTS FOUND IN HUMAN SKELETAL MUSCLE (2007)

Nicola Cannata, Chiara Romualdi, Paolo Laveder, Gerolamo Lanfranchi, Giorgio Valle

TRAIT [1] is a knowledgebase integrating information on human transcripts to related data from genome, proteins, ortholog genes, gene ontology, diseases and expression data based both on ESTs...

Genes involved in TGFβ1-driven epithelial-mesenchymal transition of renal epithelial cells are topologically related in the human interactome map (2007)

Campanaro, Stefano, Picelli, Simone, Torregrossa, Rossella, Colluto, Laura, Ceol, Monica, Del Prete, Dorella, ...

Abstract Background Understanding how mesenchymal cells arise from epithelial cells could have a strong impact in unveiling mechanisms of epithelial cell plasticity underlying kidney regeneration and...

A global gene evolution analysis on Vibrionaceaefamily using phylogenetic profile (2007)

Vitulo, Nicola, Vezzi, Alessandro, Romualdi, Chiara, Campanaro, Stefano, Valle, Giorgio

Abstract Background Vibrionaceae represent a significant portion of the cultivable heterotrophic sea bacteria; they strongly affect nutrient cycling and some species are devastating pathogens. In...

Characterization and Evolution of the Cell Cycle-Associated Mob Domain-Containing Proteins in Eukaryotes (2007)

Nicola Vitulo, Alessandro Vezzi, Giulio Galla, Sandra Citterio, Giada Marino, Benedetto Ruperti, ...

The MOB family includes a group of cell cycle-associated proteins highly conserved throughout eukaryotes, whose founding members are implicated in mitotic exit and co-ordination of cell cycle...

Genes involved in TGF?1-driven epithelial-mesenchymal transition of renal epithelial cells are topologically related in the human interactome map (2007)

Campanaro, Stefano, Picelli, Simone, Terragrossa, Rossella, Colluto, Laura, Ceol, Monica, Del Prete, Dorella, ...

Background Understanding how mesenchymal cells arise from epithelial cells could have a strong impact in unveiling mechanisms of epithelial cell plasticity underlying kidney regeneration and repair....

A global gene evolution analysis on Vibrionaceae family using phylogenetic profile (2007)

Vitulo, Nicola, Vezzi, Alessandro, Romualdi, Chiara, Campanaro, Stefano, Valle, Giorgio

Background Vibrionaceae represent a significant portion of the cultivable heterotrophic sea bacteria; they strongly affect nutrient cycling and some species are devastating pathogens. In this work we...

BioMed Central (2007)

Bmc Genomics, Stefano Campanaro, Simone Picelli, Rossella Torregrossa, Laura Colluto, Monica Ceol, ...

Research article Genes involved in TGFβ1-driven epithelial-mesenchymal transition of renal epithelial cells are topologically related in the human interactome map

Overview of BITS2005, the Second Annual Meeting of the Italian Bioinformatics Society (2005)

Helmer-Citterich, Manuela, Casadio, Rita, Guffanti, Alessandro, Mauri, Giancarlo, Milanesi, Luciano, Pesole, Graziano, ...

Abstract The BITS2005 Conference brought together about 200 Italian scientists working in the field of Bioinformatics, students in Biology, Computer Science and Bioinformatics on March 17–19 2005,...

Laterally transferred elements and high pressure adaptation in Photobacterium profundumstrains (2005)

Campanaro, Stefano, Vezzi, Alessandro, Vitulo, Nicola, Lauro, Federico M, D'Angelo, Michela, Simonato, Francesca, ...

Abstract Background Oceans cover approximately 70% of the Earth's surface with an average depth of 3800 m and a pressure of 38 MPa, thus a large part of the biosphere is occupied by high pressure...

Laterally transferred elements and high pressure adaptation in Photobacterium profundum strains (2005)

Campanaro, Stefano, Vezzi, Alessandro, Vitulo, Nicola, Lauro, Federico M, D'Angelo, Michela, Simonato, Francesca, ...

Background Oceans cover approximately 70% of the Earth's surface with an average depth of 3800 m and a pressure of 38 MPa, thus a large part of the biosphere is occupied by high pressure...

Overview of BITS2005, the Second Annual Meeting of the Italian Bioinformatics Society (2005)

Helmer-Citterich, Manuela, Casadio, Rita, Guffanti, Alessandro, Mauri, Giancarlo, Milanesi, Luciano, Pesole, Graziano, ...

The BITS2005 Conference brought together about 200 Italian scientists working in the field of Bioinformatics, students in Biology, Computer Science and Bioinformatics on March 17–19 2005, in Milan....

RAP: a new computer program for de novo identification of repeated sequences in whole genomes (2005)

Campagna, Davide, Romualdi, Chiara, Vitulo, Nicola, Del Favero, Micky, Lexa, Matej, Cannata, Nicola, ...

Motivation: DNA repeats are a common feature of most genomic sequences. Their de novo identification is still difficult despite being a crucial step in genomic analysis and oligonucleotides design....

The SSEA server for protein secondary structure alignment (2005)

Fontana, Paolo, Bindewald, Eckart, Toppo, Stefano, Velasco, Riccardo, Valle, Giorgio, Tosatto, Silvio C. E.

Summary: We present a web server that computes alignments of protein secondary structures. The server supports both performing pairwise alignments and searching a secondary structure against a...

Continuous Learning Relaxing Time & Location Constraints In a Regular Curricula Degree Offered by University of Milan. (2004)

FOLGIERI, RAFFAELLA, VALLE, GIORGIO, Giorgio Valle, Raffaella Folgieri

Continuous Learning Relaxing Time & Location Constraints In a Regular Curricula Degree Offered by University of Milan. / Giorgio Valle, Raffaella Folgieri. - (Volume 2004, issue 1). - In: Proceedings...

BIOINFORMATICS ORIGINAL PAPER Sequence analysis RAP: a new computer program for de novo identification of repeated sequences in whole genomes (2004)

Davide Campagna, Chiara Romualdi, Nicola Vitulo, Micky Del Favero, Matej Lexa, Nicola Cannata, ...

Motivation: DNA repeats are a common feature of most genomic sequences. Their de novo identification is still difficult despite being a crucial step in genomic analysis and oligonucleotides design....

The Mitochondrial Genome of the House Centipede Scutigera and the Monophyly vs. Paraphyly of Myriapods (2004)

Negrisolo, Enrico, Minelli, Alessandro, Valle, Giorgio

Recent advances in molecular phylogenetics are continuously changing our perception of the phylogenetic relationships among the main arthropod lineages: crustaceans, hexapods, chelicerates and...

The SSEA server for protein secondary structure alignment (2004)

Fontana, Paolo, Bindewald, Eckart, Toppo, Stefano, Velasco, Riccardo, Valle, Giorgio, Tosatto, Silvio C. E.

Summary: We present a web server which computes alignments of protein secondary structures. The server supports both performing pairwise alignments and searching a secondary structure against a...

RAP: a new computer program for de novo identification of repeated sequences in whole genomes (2004)

Campagna, Davide, Romualdi, Chiara, Vitulo, Nicola, Del Favero, Micky, Lexa, Matej, Cannata, Nicola, ...

Motivation: DNA repeats are a common feature of most genomic sequences. Their de novo identification is still difficult despite being a crucial step in genomic analysis and oligonucleotides design....

The Mitochondrial Genome of the House Centipede Scutigera and the Monophyly Versus Paraphyly of Myriapods (2004)

Negrisolo, Enrico, Minelli, Alessandro, Valle, Giorgio

Recent advances in molecular phylogenetics are continuously changing our perception of the phylogenetic relationships among the main arthropod lineages: crustaceans, hexapods, chelicerates, and...

The Mitochondrial Genome of the House Centipede Scutigera and the Monophyly vs. Paraphyly of Myriapods (2004)

Negrisolo, Enrico, Minelli, Alessandro, Valle, Giorgio

Recent advances in molecular phylogenetics are continuously changing our perception of the phylogenetic relationships among the main arthropod lineages: crustaceans, hexapods, chelicerates and...

The SSEA server for protein secondary structure alignment (2004)

Fontana, Paolo, Bindewald, Eckart, Toppo, Stefano, Velasco, Riccardo, Valle, Giorgio, Tosatto, Silvio C. E.

Summary: We present a web server which computes alignments of protein secondary structures. The server supports both performing pairwise alignments and searching a secondary structure against a...

RAP: a new computer program for de novo identification of repeated sequences in whole genomes (2004)

Campagna, Davide, Romualdi, Chiara, Vitulo, Nicola, Del Favero, Micky, Lexa, Matej, Cannata, Nicola, ...

Motivation: DNA repeats are a common feature of most genomic sequences. Their de novo identification is still difficult despite being a crucial step in genomic analysis and oligonucleotides design....

PRIMEX: rapid identification of oligonucleotide matches in whole genomes (2003)

Lexa, Matej, Valle, Giorgio

Summary: PRIMEX (PRImer Match EXtractor) can detect oligonucleotide sequences in whole genomes, allowing for mismatches. Using a word lookup table and server functionality, PRIMEX accepts queries...

TRAIT (TRAnscript Integrated Table): a knowledgebase of human skeletal muscle transcripts (2003)

Toppo, Stefano, Cannata, Nicola, Fontana, Paolo, Romualdi, Chiara, Laveder, Paolo, Bertocco, Emanuela, ...

Summary: TRAIT is a knowledgebase integrating information on transcripts with related data from genome, proteins, ortholog genes and diseases. It was initially built as a system to manage an...

Simple consensus procedures are effective and sufficient in secondary structure prediction (2003)

Albrecht, Mario, Tosatto, Silvio C.E., Lengauer, Thomas, Valle, Giorgio

We have analyzed the performance of majority voting on minimal combination sets of three state‐of‐the‐art secondary structure prediction methods in order to obtain a consensus...

Pattern recognition in gene expression profiling using DNA array: a comparative study of different statistical methods applied to cancer classification (2003)

Romualdi, Chiara, Campanaro, Stefano, Campagna, Davide, Celegato, Barbara, Cannata, Nicola, Toppo, Stefano, ...

Large-scale parallel measurements of the expression of many thousands genes are now available with high-density array made with collections of cDNA fragments, or oligonucleotide corresponding to...

Development and production of an oligonucleotide MuscleChip: use for validation of ambiguous ESTs (2002)

Borup, Rehannah HA, Toppo, Stefano, Chen, Yi-Wen, Teslovich, Tanya M, Lanfranchi, Gerolamo, Valle, Giorgio, ...

Abstract Background We describe the development, validation, and use of a highly redundant 120,000 oligonucleotide microarray (MuscleChip) containing 4,601 probe sets representing 1,150 known genes...

Development and production of an oligonucleotide MuscleChip: use for validation of ambiguous ESTs (2002)

Borup, Rehannah HA, Toppo, Stefano, Chen, Yi-Wen, Teslovich, Tanya M, Lanfranchi, Gerolamo, Valle, Giorgio, ...

Background We describe the development, validation, and use of a highly redundant 120,000 oligonucleotide microarray (MuscleChip) containing 4,601 probe sets representing 1,150 known genes expressed...

Gene expression profiling in dysferlinopathies using a dedicated muscle microarray (2002)

Campanaro, Stefano, Romualdi, Chiara, Fanin, Marina, Celegato, Barbara, Pacchioni, Beniamina, Trevisan, Silvia, ...

We have performed expression profiling to define the molecular changes in dysferlinopathy using a novel dedicated microarray platform made with 3′-end skeletal muscle cDNAs. Eight dysferlinopathy...

Simplifying amino acid alphabets by means of a branch and bound algorithm and substitution matrices (2002)

Cannata, Nicola, Toppo, Stefano, Romualdi, Chiara, Valle, Giorgio

Motivation: Protein and DNA are generally represented by sequences of letters. In a number of circumstances simplified alphabets (where one or more letters would be represented by the same symbol)...

A two-step strategy for constructing specifically self-subtracted cDNA libraries (2002)

Laveder, Paolo, De Pittà, Cristiano, Toppo, Stefano, Valle, Giorgio, Lanfranchi, Gerolamo

We have developed a new strategy for producing subtracted cDNA libraries that is optimized for connective and epithelial tissues, where a few exceptionally abundant (super-prevalent) RNA species...

Discover 1: a new program to search for unusually represented DNA motifs (1993)

Valle, Giorgio

DISCOVER1 (Distribution COunter VERsion 1) is a new program that can identify DNA motifs occurring with a high deviation from the expected frequency. The program generates families of patterns, each...

A two-step strategy for constructing specifically self-subtracted cDNA libraries

Laveder, Paolo, De Pittà, Cristiano, Toppo, Stefano, Valle, Giorgio, Lanfranchi, Gerolamo

We have developed a new strategy for producing subtracted cDNA libraries that is optimized for connective and epithelial tissues, where a few exceptionally abundant (super-prevalent) RNA species...

A Comprehensive, High-Resolution Genomic Transcript Map of Human Skeletal Muscle

Bortoluzzi, Stefania, Rampoldi, Luca, Simionati, Barbara, Zimbello, Rosanna, Barbon, Alessandro, D’Alessi, Fabio, ...

We present the Human Muscle Gene Map (HMGM), the first comprehensive and updated high-resolution expression map of human skeletal muscle. The 1078 entries of the map were obtained by merging data...

Do the Four Clades of the mtDNA Haplogroup L2 Evolve at Different Rates?

Torroni, Antonio, Rengo, Chiara, Guida, Valentina, Cruciani, Fulvio, Sellitto, Daniele, Coppa, Alfredo, ...

Forty-seven mtDNAs collected in the Dominican Republic and belonging to the African-specific haplogroup L2 were studied by high-resolution RFLP and control-region sequence analyses. Four sets of...

Haplogroup Effects and Recombination of Mitochondrial DNA: Novel Clues from the Analysis of Leber Hereditary Optic Neuropathy Pedigrees

Carelli, Valerio, Achilli, Alessandro, Valentino, Maria Lucia, Rengo, Chiara, Semino, Ornella, Pala, Maria, ...

The mitochondrial DNA (mtDNA) of 87 index cases with Leber hereditary optic neuropathy (LHON) sequentially diagnosed in Italy, including an extremely large Brazilian family of Italian maternal...

A two-step strategy for constructing specifically self-subtracted cDNA libraries

Laveder, Paolo, De Pittà, Cristiano, Toppo, Stefano, Valle, Giorgio, Lanfranchi, Gerolamo

We have developed a new strategy for producing subtracted cDNA libraries that is optimized for connective and epithelial tissues, where a few exceptionally abundant (super-prevalent) RNA species...

A Comprehensive, High-Resolution Genomic Transcript Map of Human Skeletal Muscle

Bortoluzzi, Stefania, Rampoldi, Luca, Simionati, Barbara, Zimbello, Rosanna, Barbon, Alessandro, D’Alessi, Fabio, ...

We present the Human Muscle Gene Map (HMGM), the first comprehensive and updated high-resolution expression map of human skeletal muscle. The 1078 entries of the map were obtained by merging data...

Do the Four Clades of the mtDNA Haplogroup L2 Evolve at Different Rates?

Torroni, Antonio, Rengo, Chiara, Guida, Valentina, Cruciani, Fulvio, Sellitto, Daniele, Coppa, Alfredo, ...

Forty-seven mtDNAs collected in the Dominican Republic and belonging to the African-specific haplogroup L2 were studied by high-resolution RFLP and control-region sequence analyses. Four sets of...

Haplogroup Effects and Recombination of Mitochondrial DNA: Novel Clues from the Analysis of Leber Hereditary Optic Neuropathy Pedigrees

Carelli, Valerio, Achilli, Alessandro, Valentino, Maria Lucia, Rengo, Chiara, Semino, Ornella, Pala, Maria, ...

The mitochondrial DNA (mtDNA) of 87 index cases with Leber hereditary optic neuropathy (LHON) sequentially diagnosed in Italy, including an extremely large Brazilian family of Italian maternal...

Overview of BITS2005, the Second Annual Meeting of the Italian Bioinformatics Society

Helmer-Citterich, Manuela, Casadio, Rita, Guffanti, Alessandro, Mauri, Giancarlo, Milanesi, Luciano, Pesole, Graziano, ...

The BITS2005 Conference brought together about 200 Italian scientists working in the field of Bioinformatics, students in Biology, Computer Science and Bioinformatics on March 17–19 2005, in Milan....

A Septin-based Hierarchy of Proteins Required for Localized Deposition of Chitin in the Saccharomyces cerevisiae Cell Wall

DeMarini, Douglas J., Adams, Alison E.M., Fares, Hanna, Virgilio, Claudio De, Valle, Giorgio, Chuang, John S., ...

Just before bud emergence, a Saccharomyces cerevisiae cell forms a ring of chitin in its cell wall; this ring remains at the base of the bud as the bud grows and ultimately forms part of the bud scar...

Large-Scale Transposon Mutagenesis of Photobacterium profundum SS9 Reveals New Genetic Loci Important for Growth at Low Temperature and High Pressure▿

Lauro, Federico M., Tran, Khiem, Vezzi, Alessandro, Vitulo, Nicola, Valle, Giorgio, Bartlett, Douglas H.

Microorganisms adapted to piezopsychrophilic growth dominate the majority of the biosphere that is at relatively constant low temperatures and high pressures, but the genetic bases for the...

Annotating genomes with massive-scale RNA sequencing

Denoeud, France, Aury, Jean-Marc, Da Silva, Corinne, Noel, Benjamin, Rogier, Odile, Delledonne, Massimo, ...

A method for de novo genome annotation using high-throughput cDNA sequencing data.

Characterization and Evolution of the Cell Cycle-Associated Mob Domain-Containing Proteins in Eukaryotes

Vitulo, Nicola, Vezzi, Alessandro, Galla, Giulio, Citterio, Sandra, Marino, Giada, Ruperti, Benedetto, ...

The MOB family includes a group of cell cycle-associated proteins highly conserved throughout eukaryotes, whose founding members are implicated in mitotic exit and co-ordination of cell cycle...

A Class III PDZ Binding Motif in the Myotilin and FATZ Families Binds Enigma Family Proteins: a Common Link for Z-Disc Myopathies▿

Von Nandelstadh, Pernilla, Ismail, Mohamed, Gardin, Chiara, Suila, Heli, Zara, Ivano, Belgrano, Anna, ...

Interactions between Z-disc proteins regulate muscle functions and disruption of these interactions results in muscle disorders. Mutations in Z-disc components myotilin, ZASP/Cypher, and FATZ-2...