Giovanni Destro-Bisol

Clines of nuclear DNA markers suggest a largely Neolithic ancestry of the European gene pool

Chikhi, Lounès, Destro-Bisol, Giovanni, Bertorelle, Giorgio, Pascali, Vincenzo, Barbujani, Guido

Comparisons between archaeological findings and allele frequencies at protein loci suggest that most genes of current Europeans descend from populations that have been expanding in Europe in the last...

Clines of nuclear DNA markers suggest a largely Neolithic ancestry of the European gene pool

Chikhi, Lounès, Destro-Bisol, Giovanni, Bertorelle, Giorgio, Pascali, Vincenzo, Barbujani, Guido

Comparisons between archaeological findings and allele frequencies at protein loci suggest that most genes of current Europeans descend from populations that have been expanding in Europe in the last...

Evidence for Balancing Selection from Nucleotide Sequence Analyses of Human G6PD

Verrelli, Brian C., McDonald, John H., Argyropoulos, George, Destro-Bisol, Giovanni, Froment, Alain, Drousiotou, Anthi, ...

Glucose-6-phosphate dehydrogenase (G6PD) mutations that result in reduced enzyme activity have been implicated in malarial resistance and constitute one of the best examples of selection in the human...

A Back Migration from Asia to Sub-Saharan Africa Is Supported by High-Resolution Analysis of Human Y-Chromosome Haplotypes

Cruciani, Fulvio, Santolamazza, Piero, Shen, Peidong, Macaulay, Vincent, Moral, Pedro, Olckers, Antonel, ...

The variation of 77 biallelic sites located in the nonrecombining portion of the Y chromosome was examined in 608 male subjects from 22 African populations. This survey revealed a total of 37 binary...

The Effective Mutation Rate at Y Chromosome Short Tandem Repeats, with Application to Human Population-Divergence Time

Zhivotovsky, Lev A., Underhill, Peter A., Cinnioğlu, Cengiz, Kayser, Manfred, Morar, Bharti, Kivisild, Toomas, ...

We estimate an effective mutation rate at an average Y chromosome short-tandem repeat locus as 6.9×10-4 per 25 years, with a standard deviation across loci of 5.7×10-4, using data on microsatellite...

Inferring Human Population Sizes, Divergence Times and Rates of Gene Flow From Mitochondrial, X and Y Chromosome Resequencing Data

Garrigan, Daniel, Kingan, Sarah B., Pilkington, Maya M., Wilder, Jason A., Cox, Murray P., Soodyall, Himla, ...

We estimate parameters of a general isolation-with-migration model using resequence data from mitochondrial DNA (mtDNA), the Y chromosome, and two loci on the X chromosome in samples of 25–50...

Testing for Archaic Hominin Admixture on the X Chromosome: Model Likelihoods for the Modern Human RRM2P4 Region From Summaries of Genealogical Topology Under the Structured Coalescent

Cox, Murray P., Mendez, Fernando L., Karafet, Tatiana M., Pilkington, Maya Metni, Kingan, Sarah B., Destro-Bisol, Giovanni, ...

A 2.4-kb stretch within the RRM2P4 region of the X chromosome, previously sequenced in a sample of 41 globally distributed humans, displayed both an ancient time to the most recent common ancestor...