Giselda Bucca

Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon (2009)

Bucca, Giselda, Laing, Emma, Mersinias, Vassilis, Allenby, Nicholas, Hurd, Douglas, Holdstock, Jolyon, ...

Abstract Background DNA microarrays are a key resource for global analysis of genome content, gene expression and the distribution of transcription factor binding sites. We describe the development...

NepA is a structural cell wall protein involved in maintenance of spore dormancy in Streptomyces coelicolor (2009)

Jong, Wouter De, Manteca, Angel, Sanchez, Jesus, Bucca, Giselda, Smith, Colin P., Dijkhuizen, Lubbert, ...

Streptomycetes have a complex morphogenetic programme culminating in the formation of aerial hyphae that develop into chains of spores. After spore dispersal, environmental signals trigger dormant...

New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures (2007)

Hesketh, Andy, Bucca, Giselda, Laing, Emma, Flett, Fiona, Hotchkiss, Graham, Smith, Colin P, ...

Abstract Background In Streptomyces coelicolor , bldA encodes the only tRNA for a rare leucine codon, UUA. This tRNA is unnecessary for growth, but is required for some aspects of secondary...

A bacterial hormone (the SCB1) directly controls the expression of a pathway-specific regulatory gene in the cryptic type I polyketide biosynthetic gene cluster of Streptomyces coelicolor (2005)

Takano, Eriko, Kinoshita, Hiroshi, Mersinias, Vassilis, Bucca, Giselda, Hotchkiss, Graham, Nihira, Takuya, ...

Gamma-butyrolactone signalling molecules are produced by many Streptomyces species, and several have been shown to regulate antibiotic production. In Streptomyces coelicolor A3(2) at least one...

New pleiotropic effects of eliminating a rare tRNA from Streptomyces coelicolor, revealed by combined proteomic and transcriptomic analysis of liquid cultures

Hesketh, Andy, Bucca, Giselda, Laing, Emma, Flett, Fiona, Hotchkiss, Graham, Smith, Colin P, ...

Development and application of versatile high density microarrays for genome-wide analysis of Streptomyces coelicolor: characterization of the HspR regulon

Bucca, Giselda, Laing, Emma, Mersinias, Vassilis, Allenby, Nicholas, Hurd, Douglas, Holdstock, Jolyon, ...

Development of high-density microarrays for global analysis of gene expression and transcription factor binding in Streptomyces coelicolor suggests a novel role for HspR in stress adaptation.