GK Eaglesham

Hepatic xenobiotic metabolism of cylindrospermopsin in vivo in the mouse (2002)

Norris, RLG, Seawright, AA, Shaw, GR, Senogles, P, Eaglesham, GK, Smith, MJ, ...

Cylindrospermopsin (CYN) is a hepatotoxin isolated from the blue-green alga Cylindrospermopsis raciborskii. The role of both glutathione (GSH) and the cytochrome P450 enzyme system (P450) in the...

Extraction and purification of the zwitterions cylindrospermopsin and deoxycylindrospermopsin from Cylindrospermopsis raciborskii (2001)

Norris, RLG, Eaglesham, GK, Shaw, GR, Senogles, P, Chiswell, RK, Smith, MJ, ...

The hepatotoxin cylindrospermopsin (CYN) has been isolated from the cyanobacterium Cylindrospermopsis raciborskii (C. raci.). Efforts to study this toxin have been hampered by the time-consuming...

A sensitive and specific assay for glutathione with potential application to glutathione disulphide, using high-performance liquid chromatography-tandem mass spectrometry (2001)

Norris, RL, Eaglesham, GK, Shaw, GR, Smith, MJ, Chiswell, RK, Seawright, AA, ...

We have utilised the combination of sensitivity and specificity afforded by coupling high-performance liquid chromatography (HPLC) to a tandem mass spectrometer (MS-MS) to produce an assay which is...

Use of HPLC-MS/MS to monitor cylindrospermopsin, a blue-green algal toxin, for public health purposes (1999)

Eaglesham, GK, Norris, RL, Shaw, GR, Smith, MJ, Chiswell, RK, Davis, BC, ...

Increasing reports of blooms of the blue-green alga Cylindrospermopsis raciborskii (C. raciborskii), which contains the hepatotoxic alkaloid cylindrospermopsin (CYN), have led to public health...

Blooms of the cylindrospermopsin containing cyanobacterium, Aphanizomenon ovalisporum (Forti), in newly constructed lakes, Queensland, Australia (1999)

Shaw, GR, Sukenik, A, Livne, A, Chiswell, RK, Smith, MJ, Seawright, AA, ...

The cyanobacterium, Aphanizomenon ovalisporum (Forti) is reported herein for the first time in Australia. Its distribution appears to be restricted to an isolated subtropical region which has...

Deoxycylindrospermopsin, an analog of cylindrospermopsin from Cylindrospermopsis raciborskii (1999)

Norris, RL, Eaglesham, GK, Pierens, G, Shaw, GR, Smith, MJ, Chiswell, RK, ...

Cylindrospermopsin (CYN) is a hepatotoxic alkaloid found in the blue-green alga Cylindrospermopsis raciborskii (C. raciborskii). Data indicating CYN alone does not account for the toxicity of freeze...