Sabina Mahmood, Kazumi Togawa, Miwa Kawanaka, Gouichi Niiyama, Gotaro Yamada
The risk of Hepatocellular carcinoma (HCC) is high in HCV-infected patients who have biochemically and histologically active chronic hepatitis. To observe the long prognosis of Chronic Hepatitis C...
To analyze the appearance of three forms of hepatitis B antigen-associated particles (HB Ag particles) and antigen-antibody (Ag-Ab) complexes in the sera of patients with various liver diseases,...
Yamada, Gotaro, Takahashi, Takashi, Mizuno, Motowo, Sakamoto, Yuji, Kaga, Kazumi, Kobayashi, Toshinari, ...
A recently modified method using peroxidase labeled antibodies for light and electron microscopic demonstration of hepatitis B virus (HBV) was applied to the evaluation of hepatitis B surface antigen...
Mizuno, Motowo, Yamada, Gotaro, Sakamoto, Yuzi, Yumoto, Yasuhiro, Nagashima, Hideo
Antibody to hepatitis B core antigen (anti-HBc) was measured by radioimmunoassay using CORAB (Abbott Laboratories) in 10 cases of chronic persistent hepatitis (CPH), 46 cases of chronic aggressive...
Hepatitis B virus associated particles in the bile canaliculus. (2007)
Yamada, Gotaro, Sakamoto, Yuji, Mizuno, Motowo, Kobayashi, Toshinari, Nagashima, Hideo
The liver biopsy specimen from a patient with hepatitis B surface antigen was pbserved by electron microscopy. Dane particles, uncoated core particles and tubular forms were demonstrated in...
Mizuno, Motowo, Yamada, Gotaro, Sakamoto, Yuzi, Nishihara, Takashi, Yumoto, Yasuhiro, Moritsugu, Yasuo, ...
Serum specimens from 12 patients with type A hepatitis were analyzed for immunoglobulin M-type antibody to hepatitis A virus (IgM anti-HA). A recently developed solid-phase radioimmunoassay kit for...
Nishimoto, Hiroshi, Yamada, Gotaro, Mizuno, Motowo, Tsuji, Takao
We studied the distribution of class 1 and class 2 major histocompatibility complex (MHC) antigens on bile duct epithelial cells in liver from patients with primary biliary cirrhosis (PBC) by an...
Intrafamilial clustering of genotypes of hepatitis C virus RNA. (2007)
Takahashi, Michiko, Yamada, Gotaro, Doi, Toshihiko, Takatani, Masahiro, Kishi, Fumitoshi, Miyamoto, Rieko, ...
Hepatitis C virus (HCV)-RNA in the blood was measured by polymerase chain reaction (PCR) in 37 subjects from eight families in which 2 or more persons tested seropositive for antibodies against...
Endo, Hisashi, Yamada, Gotaro, Nakane, Paul K, Tsuji, Takao
To establish the most proper method of in situ hybridization in detection of HCV-RNA in the liver, various detailed procedures were examined using frozen as well as paraffin-embedded sections of...
Takahashi, Michiko, Yamada, Gotaro, Miyamoto, Rieko, Doi, Toshihiko, Endo, Hisashi, Nishimoto, Hiroshi, ...
We measured hepatitis C virus antibody titers in 13 patients with chronic hepatitis C to determine whether titration of hepatitis C virus antibody was useful or not, to predict and evaluate the...
Matsueda, Kazuhiro, Yamada, Gotaro, Tsuji, Takao
In order to clarify difference of the mucosal immunity in various sites of normal large and small intestines, we studied the population of lymphocyte subsets and immunoglobulin (Ig)-containing cells...
Tubular structures in the hepatic nuclei of a patient with delta agent. (2007)
Yamada, Gotaro, Manabe, Koji, Nagashima, Hideo
Liver biopsy specimens obtained from a 31-year-old female with delta-positive hepatitis were studied by routine electron microscopy. In several nuclei of hepatocytes, there were filamentous or...
Clinical and histological features of sporadic non-A, non-B hepatitis. (2007)
Hyodo, Ichinosuke, Yamada, Gotaro, Nishihara, Takashi, Okushin, Hiroaki, Kinoyama, Shingo, Sakamoto, Yuji, ...
The incidence of hepatitis A (HA), hepatitis B (HB), and non-A, non-B hepatitis (NANBH) was 27%, 30% and 43% among 73 patients with sporadic hepatitis. Epidemiological data (geographical...
Yamada, Gotaro, Mizuno, Motowo, Kinoyama, Shingo, Nishihara, Takashi, Okushin, Hiroaki, Hyodo, Ichinosuke, ...
In 144 cases of hepatocellular carcinoma (HCC), 166 cases of cirrhosis without HCC and 142 cases of chronic hepatitis, we examined HBsAg, anti-HBs and anti-HBc in sera and compared the following...
Clinical significance of eosinophilia in the diagnosis of halothane-induced liver injury. (2007)
Fujiwara, Masachika, Watanabe, Akiharu, Sato, Yasumasa, Shiota, Tetsuya, Nakatsukasa, Harushige, Yamada, Gotaro, ...
Three patients with severe halothane-induced liver injury are described. All patients received halothane anesthesia twice within a short period. High fever and jaundice were noticed soon after the...
Mahmood, Sabina, Togawa, Kazumi, Kawanaka, Miwa, Niiyama, Gouichi, Yamada, Gotaro
The risk of Hepatocellular carcinoma (HCC) is high in HCV-infected patients who have biochemically and histologically active chronic hepatitis. To observe the long prognosis of Chronic Hepatitis C...
Association of primary biliary cirrhosis with idiopathic thrombocytopenic purpura
Toshikuni, Nobuyuki, Yamato, Ryumei, Kobashi, Haruhiko, Nishino, Ken, Inada, Nobu, Sakanoue, Ritsuko, ...
Although both primary biliary cirrhosis (PBC) and idiopathic thrombocytopenic purpura (ITP) are autoimmune diseases, the association of the 2 diseases is rare. Here, we report a case of ITP that...
Matsuura, Kentaro, Tanaka, Yasuhito, Hige, Shuhei, Yamada, Gotaro, Murawaki, Yoshikazu, Komatsu, Masafumi, ...
Acute hepatitis B virus (HBV) infection has been increasing through promiscuous sexual contacts, and HBV genotype A (HBV/A) is frequent in patients with acute hepatitis B (AHB) in Japan. To compare...