Taylor, Graham P, Goon, Peter, Furukawa, Yoshitaka, Green, Hannah, Barfield, Anna, Mosley, Angelina, ...
Abstract Background No therapies have been proven to persistently improve the outcome of HTLV-I-associated myelopathy. Clinical benefit has been reported with zidovudine and with lamivudine in...
Quantification of the virus-host interaction in human T lymphotropic virus I infection (2005)
Asquith, Becca, Mosley, Angelina J, Heaps, Adrian, Tanaka, Yuetsu, Taylor, Graham P, McLean, Angela R, ...
Abstract Background HTLV-I causes the disabling inflammatory disease HAM/TSP: there is no vaccine, no satisfactory treatment and no means of assessing the risk of disease or prognosis in infected...
Murphy, Edward, Jacobson, Steven, Franchini, Genoveffa, Taylor, Graham P, Hanchard, Barrie, Morgan, Owen, ...
Abstract Human T-lymphotropic virus type 1 (HTLV-1) and HTLV-2 were among the first human retroviruses discovered in the early 1980's. The International Retrovirology Association is an organized...
Lau, Alan, Nightingale, Simon, Taylor, Graham P., Gant, Timothy W., Cann, Alan J.
Overexpression of P-glycoprotein (P-gp), the protein product of the multidrug resistance gene (MDR1), confers a drug resistant phenotype on cells. This phenotype is reminiscent of human T-cell...
Jeffery, Katie J. M., Usuku, Koichiro, Hall, Sarah E., Matsumoto, Wataru, Taylor, Graham P., Procter, Jeanette, ...
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load. However, it is...
Morozov, Vladimir A., Lagaye, Sylvie, Taylor, Graham P., Matutes, Estella, Weiss, Robin A.
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other diseases....
Saito, Mineki, Taylor, Graham P., Saito, Akiko, Furukawa, Yoshitaka, Usuku, Koichiro, Weber, Jonathan N., ...
Using HLA-peptide tetrameric complexes, we isolated human T-cell lymphotrophic virus type 1 Tax peptide-specific CD8+ T cells ex vivo. Antigen-specific amino acid motifs were identified in the T-cell...
Goon, Peter K. C., Igakura, Tadahiko, Hanon, Emmanuel, Mosley, Angelina J., Asquith, Becca, Gould, Keith G., ...
Significantly higher frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4+ T cells were present in the peripheral blood...
Murphy, Edward, Jacobson, Steven, Franchini, Genoveffa, Taylor, Graham P, Hanchard, Barrie, Morgan, Owen, ...
Human T-lymphotropic virus type 1 (HTLV-1) and HTLV-2 were among the first human retroviruses discovered in the early 1980's. The International Retrovirology Association is an organized effort that...
Labour care of women with HIV infection : Article did not highlight current guidelines
Taylor, Graham P, Lyall, E G Hermione, Tudor-Williams, Gareth, Regan, Lesley, Smith, John
Quantification of the virus-host interaction in human T lymphotropic virus I infection
Asquith, Becca, Mosley, Angelina J, Heaps, Adrian, Tanaka, Yuetsu, Taylor, Graham P, McLean, Angela R, ...
Taylor, Graham P, Goon, Peter, Furukawa, Yoshitaka, Green, Hannah, Barfield, Anna, Mosley, Angelina, ...
Jeffery, Katie J. M., Usuku, Koichiro, Hall, Sarah E., Matsumoto, Wataru, Taylor, Graham P., Procter, Jeanette, ...
The risk of disease associated with persistent virus infections such as HIV-I, hepatitis B and C, and human T-lymphotropic virus-I (HTLV-I) is strongly determined by the virus load. However, it is...
Morozov, Vladimir A., Lagaye, Sylvie, Taylor, Graham P., Matutes, Estella, Weiss, Robin A.
Human T-cell leukemia virus type 1 (HTLV-1) is the etiologic agent of adult T-cell leukemia/lymphoma (ATLL), HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP), and other diseases....
Saito, Mineki, Taylor, Graham P., Saito, Akiko, Furukawa, Yoshitaka, Usuku, Koichiro, Weber, Jonathan N., ...
Using HLA-peptide tetrameric complexes, we isolated human T-cell lymphotrophic virus type 1 Tax peptide-specific CD8+ T cells ex vivo. Antigen-specific amino acid motifs were identified in the T-cell...
Goon, Peter K. C., Igakura, Tadahiko, Hanon, Emmanuel, Mosley, Angelina J., Asquith, Becca, Gould, Keith G., ...
Significantly higher frequencies of tumor necrosis factor alpha- and interleukin-2-secreting human T-lymphotropic virus type 1 (HTLV-1)-specific CD4+ T cells were present in the peripheral blood...
Murphy, Edward, Jacobson, Steven, Franchini, Genoveffa, Taylor, Graham P, Hanchard, Barrie, Morgan, Owen, ...
Human T-lymphotropic virus type 1 (HTLV-1) and HTLV-2 were among the first human retroviruses discovered in the early 1980's. The International Retrovirology Association is an organized effort that...
Labour care of women with HIV infection : Article did not highlight current guidelines
Taylor, Graham P, Lyall, E G Hermione, Tudor-Williams, Gareth, Regan, Lesley, Smith, John
Quantification of the virus-host interaction in human T lymphotropic virus I infection
Asquith, Becca, Mosley, Angelina J, Heaps, Adrian, Tanaka, Yuetsu, Taylor, Graham P, McLean, Angela R, ...
Taylor, Graham P, Goon, Peter, Furukawa, Yoshitaka, Green, Hannah, Barfield, Anna, Mosley, Angelina, ...
In vivo T lymphocyte dynamics in humans and the impact of human T-lymphotropic virus 1 infection
Asquith, Becca, Zhang, Yan, Mosley, Angelina J., De Lara, Catherine M., Wallace, Diana L., Worth, Andrew, ...
Human T-lymphotropic virus type 1 (HTLV-1) is a persistent CD4+ T-lymphotropic retrovirus. Most HTLV-1-infected individuals remain asymptomatic, but a proportion develop adult T cell leukemia or...
Meekings, Kiran N., Leipzig, Jeremy, Bushman, Frederic D., Taylor, Graham P., Bangham, Charles R. M.
Human T-lymphotropic virus type 1 (HTLV-1) causes leukaemia or chronic inflammatory disease in ∼5% of infected hosts. The level of proviral expression of HTLV-1 differs significantly among infected...
Human T-Lymphotropic Virus-1 Visualized at the Virological Synapse by Electron Tomography
Majorovits, Endre, Nejmeddine, Mohamed, Tanaka, Yuetsu, Taylor, Graham P., Fuller, Stephen D., Bangham, Charles R. M.
Human T-lymphotropic virus 1 (HTLV-1) is transmitted directly between cells via an organized cell-cell contact called a virological synapse (VS) [1], [2]. The VS has been studied by light microscopy,...
Zhang, Yan, Wallace, Diana L, De Lara, Catherine M, Ghattas, Hala, Asquith, Becca, Worth, Andrew, ...
Human natural killer (NK) cells form a circulating population in a state of dynamic homeostasis. We investigated NK cell homeostasis by labelling dividing cells in vivo using deuterium-enriched...
Toulza, Frederic, Heaps, Adrian, Tanaka, Yuetsu, Taylor, Graham P., Bangham, Charles R. M.
Evidence from population genetics, gene expression microarrays, and assays of ex vivo T-cell function indicates that the cytotoxic T lymphocyte (CTL) response to human T-lymphotropic virus type 1...
Arginase activity mediates reversible T cell hyporesponsiveness in human pregnancy
Kropf, Pascale, Baud, David, Marshall, Sara E, Munder, Markus, Mosley, Angelina, Fuentes, José M, ...
Complex regulation of T cell functions during pregnancy is required to ensure materno-fetal tolerance. Here we reveal a novel pathway for the temporary suppression of maternal T cell responses in...
Tsukasaki, Kunihiro, Hermine, Olivier, Bazarbachi, Ali, Ratner, Lee, Ramos, Juan Carlos, Harrington, William, ...
Adult T-cell leukemia-lymphoma (ATL) is a distinct peripheral T-lymphocytic malignancy associated with a retrovirus designated human T-cell lymphotropic virus type I (HTLV-1). The diversity in...