Greg Hannon

Updates to the RMAP short-read mapping software (2009)

Smith, Andrew D., Chung, Wen-Yu, Hodges, Emily, Kendall, Jude, Hannon, Greg, Hicks, James, ...

Summary: We report on a major new version of the RMAP software for mapping reads from short-read sequencing technology. General improvements to accuracy and space requirements are included, along...

The mouse genome: Experimental examination of gene predictions and transcriptional start sites (2004)

Dike, Sujit, Balija, Vivekanand S., Nascimento, Lidia U., Xuan, Zhenyu, Ou, Jacqueline, Zutavern, Theresa, ...

The completion of the mouse and other mammalian genome sequences will provide necessary, but not sufficient, knowledge for an understanding of much of mouse biology at the molecular level. As a...

Genetic Dissection of PTEN Signaling Mechanisms in Prostate Cancer (1998)

Keniry, Megan E., Hannon, Greg, Parsons, Ramon

The goal of my traineeship is to employ genetic approaches to investigate PTEN signaling in prostate cancer. My first task was to construct expression vectors for a series of tumor-derived PTEN...

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

Alcorta, David A., Xiong, Yue, Phelps, Dawn, Hannon, Greg, Beach, David, Barrett, J. Carl

Human diploid fibroblasts (HDFs) can be grown in culture for a finite number of population doublings before they cease proliferation and enter a growth-arrest state termed replicative senescence. The...

Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells

LaMontagne, Kenneth R., Hannon, Greg, Tonks, Nicholas K.

The bcr-abl chimeric oncoprotein exhibits deregulated protein tyrosine kinase activity and is implicated in the pathogenesis of Philadelphia chromosome (Ph)-positive human leukemias, such as chronic...

Oncogene-dependent apoptosis is mediated by caspase-9

Fearnhead, Howard O., Rodriguez, Joe, Govek, Eve-Ellen, Guo, Wenjun, Kobayashi, Ryuji, Hannon, Greg, ...

Understanding how oncogenic transformation sensitizes cells to apoptosis may provide a strategy to kill tumor cells selectively. We previously developed a cell-free system that recapitulates oncogene...

The mouse genome: Experimental examination of gene predictions and transcriptional start sites

Dike, Sujit, Balija, Vivekanand S., Nascimento, Lidia U., Xuan, Zhenyu, Ou, Jacqueline, Zutavern, Theresa, ...

The completion of the mouse and other mammalian genome sequences will provide necessary, but not sufficient, knowledge for an understanding of much of mouse biology at the molecular level. As a...

Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblasts

Alcorta, David A., Xiong, Yue, Phelps, Dawn, Hannon, Greg, Beach, David, Barrett, J. Carl

Human diploid fibroblasts (HDFs) can be grown in culture for a finite number of population doublings before they cease proliferation and enter a growth-arrest state termed replicative senescence. The...

Protein tyrosine phosphatase PTP1B suppresses p210 bcr-abl-induced transformation of Rat-1 fibroblasts and promotes differentiation of K562 cells

LaMontagne, Kenneth R., Hannon, Greg, Tonks, Nicholas K.

The bcr-abl chimeric oncoprotein exhibits deregulated protein tyrosine kinase activity and is implicated in the pathogenesis of Philadelphia chromosome (Ph)-positive human leukemias, such as chronic...

Oncogene-dependent apoptosis is mediated by caspase-9

Fearnhead, Howard O., Rodriguez, Joe, Govek, Eve-Ellen, Guo, Wenjun, Kobayashi, Ryuji, Hannon, Greg, ...

Understanding how oncogenic transformation sensitizes cells to apoptosis may provide a strategy to kill tumor cells selectively. We previously developed a cell-free system that recapitulates oncogene...

The mouse genome: Experimental examination of gene predictions and transcriptional start sites

Dike, Sujit, Balija, Vivekanand S., Nascimento, Lidia U., Xuan, Zhenyu, Ou, Jacqueline, Zutavern, Theresa, ...

The completion of the mouse and other mammalian genome sequences will provide necessary, but not sufficient, knowledge for an understanding of much of mouse biology at the molecular level. As a...