Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, ...
Abstract Background Recombinational systems have been developed to rapidly shuttle Open Reading Frames (ORFs) into multiple expression vectors in order to analyze the large number of cDNAs available...
Functional requirement of p23 and Hsp90 in telomerase complexes (1999)
Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, ...
A Tetrahymena intron nucleotide connected to the GTP/arginine site (1989)
Yarus, Michael, Levine, Joseph, Morin, Gregg B., Cech, Thomas R.
We have substituted all nucleotides at intron nucleotide 260 (N260) in transcripts related to the self-splicing Tetrahymena rRNA. Substitution slightly affects the binding and reaction of GTP with...
Phylogenetic relationships and altered genome structures among Tetrahymena mitochondrial DNAs (1988)
Morin, Gregg B., Cech, Thomas R.
Tetrahymena thermophila mitochondrial DNA is a linear molecule with two tRNAs, large subunit β (LSUβ) rRNA (21S rRNA) and LSUα rRNA (5.8S-like RNA) encoded near each terminus. The DNA sequence of...
Functional requirement of p23 and Hsp90 in telomerase complexes
Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, ...
Most normal human diploid cells have no detectable telomerase; however, expression of the catalytic subunit of telomerase is sufficient to induce telomerase activity and, in many cases, will bypass...
Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, ...
Functional requirement of p23 and Hsp90 in telomerase complexes
Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, ...
Most normal human diploid cells have no detectable telomerase; however, expression of the catalytic subunit of telomerase is sufficient to induce telomerase activity and, in many cases, will bypass...
Colwill, Karen, Wells, Clark D, Elder, Kelly, Goudreault, Marilyn, Hersi, Kadija, Kulkarni, Sarang, ...
Large-scale mapping of human protein–protein interactions by mass spectrometry
Ewing, Rob M, Chu, Peter, Elisma, Fred, Li, Hongyan, Taylor, Paul, Climie, Shane, ...
Mapping protein–protein interactions is an invaluable tool for understanding protein function. Here, we report the first large-scale study of protein–protein interactions in human cells using a...