Pharmacokinetic Profile and Tolerability of Indinavir-Ritonavir Combinations in Healthy Volunteers
Saah, Alfred J., Winchell, Gregory A., Nessly, Michael L., Seniuk, Melissa A., Rhodes, Rand R., Deutsch, Paul J.
This was a randomized, double-blind, placebo-controlled parallel study in human immunodeficiency virus type 1 (HIV-1)-uninfected healthy subjects to investigate the pharmacokinetic interaction...
Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men
Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, ...
Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated...
Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma
Stone, Julie A., Xu, Xin, Winchell, Gregory A., Deutsch, Paul J., Pearson, Paul G., Migoya, Elizabeth M., ...
The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [3H]caspofungin to healthy men, plasma, urine, and...
Potential for Interactions between Caspofungin and Nelfinavir or Rifampin
Stone, Julie A., Migoya, Elizabeth M., Hickey, Lisa, Winchell, Gregory A., Deutsch, Paul J., Ghosh, Kalyan, ...
The potential for interactions between caspofungin and nelfinavir or rifampin was evaluated in two parallel-panel studies. In study A, healthy subjects received a 14-day course of caspofungin alone...
Rhame, Frank S., Rawlins, Sandy L., Petruschke, Richard A., Erb, Tara A., Winchell, Gregory A., Wilson, Helene M., ...
Human immunodeficiency virus (HIV) patients on nucleoside or nucleotide reverse transcriptase inhibitors with HIV RNA at
Pharmacokinetic Profile and Tolerability of Indinavir-Ritonavir Combinations in Healthy Volunteers
Saah, Alfred J., Winchell, Gregory A., Nessly, Michael L., Seniuk, Melissa A., Rhodes, Rand R., Deutsch, Paul J.
This was a randomized, double-blind, placebo-controlled parallel study in human immunodeficiency virus type 1 (HIV-1)-uninfected healthy subjects to investigate the pharmacokinetic interaction...
Single- and Multiple-Dose Pharmacokinetics of Caspofungin in Healthy Men
Stone, Julie A., Holland, Sherry D., Wickersham, Peter J., Sterrett, Andrew, Schwartz, Michael, Bonfiglio, Cynthia, ...
Caspofungin, a glucan synthesis inhibitor, is being developed as a parenteral antifungal agent. The pharmacokinetics of caspofungin following 1-h intravenous infusions in healthy men was investigated...
Disposition of Caspofungin: Role of Distribution in Determining Pharmacokinetics in Plasma
Stone, Julie A., Xu, Xin, Winchell, Gregory A., Deutsch, Paul J., Pearson, Paul G., Migoya, Elizabeth M., ...
The disposition of caspofungin, a parenteral antifungal drug, was investigated. Following a single, 1-h, intravenous infusion of 70 mg (200 μCi) of [3H]caspofungin to healthy men, plasma, urine, and...
Potential for Interactions between Caspofungin and Nelfinavir or Rifampin
Stone, Julie A., Migoya, Elizabeth M., Hickey, Lisa, Winchell, Gregory A., Deutsch, Paul J., Ghosh, Kalyan, ...
The potential for interactions between caspofungin and nelfinavir or rifampin was evaluated in two parallel-panel studies. In study A, healthy subjects received a 14-day course of caspofungin alone...
Rhame, Frank S., Rawlins, Sandy L., Petruschke, Richard A., Erb, Tara A., Winchell, Gregory A., Wilson, Helene M., ...
Human immunodeficiency virus (HIV) patients on nucleoside or nucleotide reverse transcriptase inhibitors with HIV RNA at