Gregory K. Pierens

Evaluation of novel Hyphodermin derivatives as Glycogen Phosphorylase a inhibitors (2008)

Loughlin, Wendy Anne, Pierens, Gregory K., Petersson, Maria Jenni, Henderson, Luke, Healy, Peter Conrad

The lipophilicity, permeability, solubility, polar surface area and 'rule-of-five' properties were assessed, using QikProp v2.5 (Schrödinger, Inc.) and ALOGPS 2.1 calculations, for 25 Hyphodermin...

Evaluation of novel Hyphodermin derivatives as Glycogen Phosphorylase a inhibitors (2008)

Loughlin, Wendy Anne, Pierens, Gregory K., Petersson, Maria Jenni, Henderson, Luke, Healy, Peter Conrad

The lipophilicity, permeability, solubility, polar surface area and 'rule-of-five' properties were assessed, using QikProp v2.5 (Schrödinger, Inc.) and ALOGPS 2.1 calculations, for 25 Hyphodermin...

Evaluation of novel Hyphodermin derivatives as Glycogen Phosphorylase a inhibitors (2008)

Loughlin, Wendy Anne, Pierens, Gregory K., Petersson, Maria Jenni, Henderson, Luke, Healy, Peter Conrad

The lipophilicity, permeability, solubility, polar surface area and 'rule-of-five' properties were assessed, using QikProp v2.5 (Schrödinger, Inc.) and ALOGPS 2.1 calculations, for 25 Hyphodermin...

Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide (2007)

Davis, Rohan A., Pierens, Gregory K., Parsons, Peter G.

Parallel solution-phase chemistry has yielded a series of secondary amide analogues of the fungal natural product 3-chloro-4-hydroxyphenylacetamide. 3-Chloro-4-hydroxyphenylacetic acid was coupled to...

Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide (2007)

Davis, Rohan A., Pierens, Gregory K., Parsons, Peter G.

Parallel solution-phase chemistry has yielded a series of secondary amide analogues of the fungal natural product 3-chloro-4-hydroxyphenylacetamide. 3-Chloro- 4-hydroxyphenylacetic acid was coupled...

Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide (2007)

Davis, Rohan A., Pierens, Gregory K., Parsons, Peter G.

Parallel solution-phase chemistry has yielded a series of secondary amide analogues of the fungal natural product 3-chloro-4-hydroxyphenylacetamide. 3-Chloro-4-hydroxyphenylacetic acid was coupled to...

Synthesis and spectroscopic characterisation of a combinatorial library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide (2007)

Davis, Rohan A., Pierens, Gregory K., Parsons, Peter G.

Parallel solution-phase chemistry has yielded a series of secondary amide analogues of the fungal natural product 3-chloro-4-hydroxyphenylacetamide. 3-Chloro- 4-hydroxyphenylacetic acid was coupled...

Synthesis and spectroscopic characteristation of a combinatoiral library based on the fungal natural product 3-chloro-4-hydroxyphenylacetamide (2007)

Davis, Rohan Andrew, Pierens, Gregory K., Parsons, Peter G.

Parallel solution-phase chemistry has yielded a series of secondary amide analogues of the fungal natural product 3-chloro-4-hydroxyphenylacetamide. 3-Chloro-4-hydroxyphenylacetic acid was coupled to...

1H and 13C NMR assignments for two new xanthones from the endophytic fungus Xylaria sp. FRR 5657 (2006)

Davis, Rohan A., Pierens, Gregory K.

The complete 1H and 13C NMR assignments are reported for the new natural products, 7-hydroxy- 3-(hydroxymethyl)-1-methoxy-9H-xanthen-9-one (1) and 2,5-dihydroxy-8-methoxy-6-methyl-9-oxo-9H-xanthene...

1H and 13C NMR assignments for two new xanthones from the endophytic fungus Xylaria sp. FRR 5657 (2006)

Davis, Rohan A., Pierens, Gregory K.

The complete 1H and 13C NMR assignments are reported for the new natural products, 7-hydroxy- 3-(hydroxymethyl)-1-methoxy-9H-xanthen-9-one (1) and 2,5-dihydroxy-8-methoxy-6-methyl-9-oxo-9H-xanthene...

1H and 13C NMR assignments for two new xanthones from the endophytic fungus xylaria sp. FRR 5657 (2006)

Davis, Rohan Andrew, Pierens, Gregory K

The complete 1H and 13C NMR assignments are reported for the new natural products, 7-hydroxy-3-(hydroxymethyl)-1-methoxy-9H-xanthen-9-one (1) and 2,5-dihydroxy-8-methoxy-6-methyl-9-oxo-9H-xanthene...

A robust clustering approach for NMR spectra of natural product extracts (2005)

Pierens, Gregory K, Palframan, Meredith Elizabeth, Tranter, Carolyn, Carroll, Anthony Richard, Quinn, Ronald J

A robust method was developed to cluster similar NMR spectra from partially purified extracts obtained from a range of marine sponges and a plant biota. The NMR data were acquired using microtiter...

Latifolians A and B, Novel JNK3 Kinase Inhibitors from the Papua New Guinean Plant Gnetum latifolium (2005)

Rochfort, Simone Jane, Towerzey, Leanne, Carroll, Anthony Richard, King, Gordon William, Michael, Adam Philip, Pierens, Gregory K, ...

As part of our search for natural products active against the JNK3 kinase, two novel, charged benzylisoquinolines, latifolian A (1) and latifolian B (2), were isolated from the stem bark of the Papua...

A robust clustering approach for NMR spectra of natural product extracts (2005)

Pierens, Gregory K, Palframan, Meredith Elizabeth, Tranter, Carolyn, Carroll, Anthony Richard, Quinn, Ronald J

A robust method was developed to cluster similar NMR spectra from partially purified extracts obtained from a range of marine sponges and a plant biota. The NMR data were acquired using microtiter...

Latifolians A and B, Novel JNK3 Kinase Inhibitors from the Papua New Guinean Plant Gnetum latifolium (2005)

Rochfort, Simone Jane, Towerzey, Leanne, Carroll, Anthony Richard, King, Gordon William, Michael, Adam Philip, Pierens, Gregory K, ...

As part of our search for natural products active against the JNK3 kinase, two novel, charged benzylisoquinolines, latifolian A (1) and latifolian B (2), were isolated from the stem bark of the Papua...

A robust clustering approach for NMR spectra of natural product extracts (2005)

Pierens, Gregory K, Palframan, Meredith Elizabeth, Tranter, Carolyn, Carroll, Anthony Richard, Quinn, Ronald J

A robust method was developed to cluster similar NMR spectra from partially purified extracts obtained from a range of marine sponges and a plant biota. The NMR data were acquired using microtiter...

Latifolians A and B, Novel JNK3 Kinase Inhibitors from the Papua New Guinean Plant Gnetum latifolium (2005)

Rochfort, Simone Jane, Towerzey, Leanne, Carroll, Anthony Richard, King, Gordon William, Michael, Adam Philip, Pierens, Gregory K, ...

As part of our search for natural products active against the JNK3 kinase, two novel, charged benzylisoquinolines, latifolian A (1) and latifolian B (2), were isolated from the stem bark of the Papua...

A robust clustering approach for NMR spectra of natural product extracts (2005)

Pierens, Gregory K., Palframan, Meredith E., Tranter, Carolyn J., Carroll, Anthony R., Quinn, Ronald J.

Abstract A robust method was developed to cluster similar NMR spectra from partially purified extracts obtained from a range of marine sponges and a plant biota. The NMR data were acquired using...

A robust clustering approach for NMR spectra of natural product extracts (2005)

Pierens, Gregory K., Palframan, Meredith E., Tranter, Carolyn J., Carroll, Anthony R., Quinn, Ronald J.

Abstract A robust method was developed to cluster similar NMR spectra from partially purified extracts obtained from a range of marine sponges and a plant biota. The NMR data were acquired using...

A robust clustering approach for NMR spectra of natural product extracts (2005)

Pierens, Gregory K, Palframan, Meredith Elizabeth, Tranter, Carolyn, Carroll, Anthony Richard, Quinn, Ronald J

A robust method was developed to cluster similar NMR spectra from partially purified extracts obtained from a range of marine sponges and a plant biota. The NMR data were acquired using microtiter...

Latifolians A and B, Novel JNK3 Kinase Inhibitors from the Papua New Guinean Plant Gnetum latifolium (2005)

Rochfort, Simone Jane, Towerzey, Leanne, Carroll, Anthony Richard, King, Gordon William, Michael, Adam Philip, Pierens, Gregory K, ...

As part of our search for natural products active against the JNK3 kinase, two novel, charged benzylisoquinolines, latifolian A (1) and latifolian B (2), were isolated from the stem bark of the Papua...

Multiple quantum nuclear magnetic resonance spectra of partially oriented styrene in a nematic phase (2003)

Ramadan, Saadallah A., Field, Leslie D., Pierens, Gregory K.

Proton multiple-quantum nuclear magnetic resonance (MQNMR) spectra of styrene partially oriented in a nematic liquid crystal were acquired using the magnetic field gradient method. Six-, seven- and...

Multiple quantum nuclear magnetic resonance spectra of partially oriented styrene in a nematic phase (2003)

Ramadan, Saadallah A., Field, Leslie D., Pierens, Gregory K.

Proton multiple-quantum nuclear magnetic resonance (MQNMR) spectra of styrene partially oriented in a nematic liquid crystal were acquired using the magnetic field gradient method. Six-, seven- and...

Multiple-quantum NMR spectra of partially oriented indene. A new approach to estimating order in a nematic phase (2002)

Field, Leslie D., Ramadan, Saadallah A., Pierens, Gregory K

Multiple-quantum proton NMR spectra of the 8-spin system of indene partially oriented in a nematic mesophase were acquired using a magnetic field gradient (MFG) method. Six-, seven- and eight-quantum...

Multiple-quantum NMR spectra of partially oriented indene. A new approach to estimating order in a nematic phase (2002)

Field, Leslie D., Ramadan, Saadallah A., Pierens, Gregory K

Multiple-quantum proton NMR spectra of the 8-spin system of indene partially oriented in a nematic mesophase were acquired using a magnetic field gradient (MFG) method. Six-, seven- and eight-quantum...

Multiple-quantum NMR spectra of partially oriented indene. A new approach to estimating order in a nematic phase (2002)

Field, Leslie D., Ramadan, Saadallah A., Pierens, Gregory K

Multiple-quantum proton NMR spectra of the 8-spin system of indene partially oriented in a nematic mesophase were acquired using a magnetic field gradient (MFG) method. Six-, seven- and eight-quantum...

Multiple-Quantum NMR Spectra of Partially Oriented Indene: A New Approach to Estimating Order in a Nematic Phase (2002)

Field, Lesley D., Ramadan, Saadallah A., Pierens, Gregory K.

Multiple-quantum proton NMR spectra of the 8-spin system of indene partially oriented in a nematic mesophase were acquired using a magnetic field gradient (MFG) method. Six-, seven- and eight-quantum...

Structural studies on sulfonylbicyclo[n.2.0]alkan-1-ols (2002)

Healy, Peter C., Loughlin, Wendy A., McCleary, Michelle A., Pierens, Gregory K., Rowen, Catherine C.

The structures of a series of sulfonylbicyclo[n.2.0]alkan-1-ols (n = 3-6) 1-6 were determined by single-crystal x-ray diffraction. A survey of the Cambridge Structural Database and Monte Carlo...

Multiple-Quantum NMR Spectra of Partially Oriented Indene: A New Approach to Estimating Order in a Nematic Phase (2002)

Field, Lesley D., Ramadan, Saadallah A., Pierens, Gregory K.

Multiple-quantum proton NMR spectra of the 8-spin system of indene partially oriented in a nematic mesophase were acquired using a magnetic field gradient (MFG) method. Six-, seven- and eight-quantum...

Structural studies on sulfonylbicyclo[n.2.0]alkan-1-ols (2002)

Healy, Peter C., Loughlin, Wendy A., McCleary, Michelle A., Pierens, Gregory K., Rowen, Catherine C.

The structures of a series of sulfonylbicyclo[n.2.0]alkan-1-ols (n = 3-6) 1-6 were determined by single-crystal x-ray diffraction. A survey of the Cambridge Structural Database and Monte Carlo...

Multiple-quantum NMR spectra of partially oriented indene. A new approach to estimating order in a nematic phase (2002)

Field, Leslie D., Ramadan, Saadallah A., Pierens, Gregory K

Multiple-quantum proton NMR spectra of the 8-spin system of indene partially oriented in a nematic mesophase were acquired using a magnetic field gradient (MFG) method. Six-, seven- and eight-quantum...

Structural studies on sulfonylbicyclo[n.2.0]alkan-1-ols (2002)

Healy, Peter Conrad, Loughlin, Wendy Anne, McCleary, Michelle Angela, Pierens, Gregory K, Rowen, Catherine Carmel

The structures of a series of sulfonylbicyclo[n.2.0]alkan-1-ols (n = 3-6) 1-6 were determined by single-crystal x-ray diffraction. A survey of the Cambridge Structural Database and Monte Carlo...

A study of the binding requirements of calyculin A and dephosphonocalyculin (2001)

Volter, Katie, Embrey, Kevin J., Pierens, Gregory K, Quinn, Ronald J

The interactions of the okadaic acid class of compounds, with special emphasis on the solution structures of calyculin A and dephosphonocalyculin A with PP1 are reported. After examination of the...

A study of the binding requirements of calyculin A and dephosphonocalyculin (2001)

Volter, Katie, Embrey, Kevin J., Pierens, Gregory K, Quinn, Ronald J

The interactions of the okadaic acid class of compounds, with special emphasis on the solution structures of calyculin A and dephosphonocalyculin A with PP1 are reported. After examination of the...

A study of the binding requirements of calyculin A and dephosphonocalyculin (2001)

Volter, Katie, Embrey, Kevin J., Pierens, Gregory K, Quinn, Ronald J

The interactions of the okadaic acid class of compounds, with special emphasis on the solution structures of calyculin A and dephosphonocalyculin A with PP1 are reported. After examination of the...

A study of the binding requirements of calyculin A and dephosphonocalyculin (2001)

Volter, Katie, Embrey, Kevin J., Pierens, Gregory K, Quinn, Ronald J

The interactions of the okadaic acid class of compounds, with special emphasis on the solution structures of calyculin A and dephosphonocalyculin A with PP1 are reported. After examination of the...