Gregory T. Crimmins

Distinct TLR- and NLR-Mediated Transcriptional Responses to an Intracellular Pathogen (2008)

Jess H. Leber, Gregory T. Crimmins, Sridharan Raghavan, Jeffery S. Cox, Daniel A. Portnoy

How the innate immune system tailors specific responses to diverse microbial infections is not well understood. Cells use a limited number of host receptors and signaling pathways to both...

Distinct TLR- and NLR-Mediated Transcriptional Responses to an Intracellular Pathogen

Leber, Jess H, Crimmins, Gregory T, Raghavan, Sridharan, Meyer-Morse, Nicole P, Cox, Jeffery S, Portnoy, Daniel A

How the innate immune system tailors specific responses to diverse microbial infections is not well understood. Cells use a limited number of host receptors and signaling pathways to both...

Listeria monocytogenes multidrug resistance transporters activate a cytosolic surveillance pathway of innate immunity

Crimmins, Gregory T., Herskovits, Anat A., Rehder, Kai, Sivick, Kelsey E., Lauer, Peter, Dubensky, Thomas W., ...

To gain insight into the interaction of intracellular pathogens with host innate immune pathways, we performed an unbiased genetic screen of Listeria monocytogenes mutants that induced an enhanced or...