Guang Chen

Pavideoge: A Metadata Markup Video Structure in Video Search Engine (2009)

Yang, Pu, Guo, Jun, Chen, Guang

In this paper, we study the problems of video processing in video search engine. Video has now become a very important kind of data in Internet; while searching for video is still a challenging task...

Cognitive Process-Based Research Support System (2009)

Yi Zeng, Jiajin Huang, Guang Chen

In this paper, we propose Cognitive Process-Based Research Support System (CPBRSS) to be a practical investigation for Web based Information Retrieval Support System (WIRSS). With the philosophy of...

Scaling and Memory Effect in Volatility Return Interval of the Chinese Stock Market (2008)

Qiu, Tian, Guo, Liang, Chen, Guang

We investigate the probability distribution of the volatility return intervals $\tau$ for the Chinese stock market. We rescale both the probability distribution $P_{q}(\tau)$ and the volatility...

Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status (2008)

Yan, Bin, Chen, Guang, Saigal, Kunal, Yang, Xinping, Jensen, Shane T, Van Waes, Carter, ...

Abstract Background Aberrant activation of the nuclear factor kappaB (NF- κ B) pathway has been previously implicated as a crucial signal promoting tumorigenesis. However, how NF- κ B acts as a key...

2-[4-(Diethylamino)phenyl]-1-ethylimidazo[4,5-f][1,10]phenanthroline. Corrigendum (2008)

Min Sun, Guang Chen, Ke-Zhi Wang

The list of authors in the paper by Sun, Chen, Ling & Liu [Acta Cryst. (2007), E63, o1210–o1211] is corrected.

Group SCAD regression analysis for microarray time course gene expression data (2007)

Wang, Lifeng, Chen, Guang, Li, Hongzhe

Motivation: Since many important biological systems or processes are dynamic systems, it is important to study the gene expression patterns over time in a genomic scale in order to capture the...

Expansion of adult beta-cell mass in response to increased metabolic demand is dependent on HNF-4{alpha} (2007)

Gupta, Rana K., Gao, Nan, Gorski, Regina K., White, Peter, Hardy, Olga T., Rafiq, Kiran, ...

The failure to expand functional pancreatic β-cell mass in response to increased metabolic demand is a hallmark of type 2 diabetes. Lineage tracing studies indicate that replication of existing...

Clustering of genes into regulons using integrated modeling-COGRIM (2007)

Chen, Guang, Jensen, Shane T, Stoeckert, Christian J

Abstract We present a Bayesian hierarchical model and Gibbs Sampling implementation that integrates gene expression, ChIP binding, and transcription factor motif data in a principled and robust...

Identifying transcriptional regulatory modules and networks by integrative approaches (2007)

Chen, Guang

There is great interest in understanding the genetic program of cellular response and differentiation. However, the transcriptional regulatory networks that specify and maintain cellular function are...

Effects of Huanglian Jiedu Decoction on glucose transporter 4 in target tissues of type 2 diabetic rats (2007)

Guang CHEN, Fu-er LU

Objective: To investigate the molecular mechanism of Huanglian Jiedu Decoction (HLJDD), a traditional Chinese compound herbal medicine, in treating type 2 diabetes mellitus (T2DM) by observing its...

Bayesian variable selection and data integration for biological regulatory networks (2006)

Jensen, Shane T., Chen, Guang, Stoeckert, Christian J.

A substantial focus of research in molecular biology are gene regulatory networks: the set of transcription factors and target genes which control the involvement of different biological processes in...

Origin of inhomogenous behavior during equal channel angular pressing (2006)

Wei, Wei, Nagasekhar, A. V., Chen, Guang, Tick-Hon, Yip, Wei, Kun Xia

The influence of the outer angle, friction conditions and deformation dead zone (DDZ) on inhomogenous behavior during equal channel angular pressing was investigated by a grid experiment and finite...

Defining the mammalian CArGome (2005)

Sun, Qiang, Chen, Guang, Streb, Jeffrey W., Long, Xiaochun, Yang, Yumei, Stoeckert, Christian J., ...

Serum response factor (SRF) binds a 1216-fold degenerate cis element known as the CArG box. CArG boxes are found primarily in muscle- and growth-factor-associated genes although the full spectrum of...

Design and characterization of ESD protection for RFICs / (2003)

Chen, Guang.

Thesis (M.S.)--Illinois Institute of Technology, 2003.

Gauged Q ball in a piecewise parabolic potential (2002)

Li, Xin-zhou, Hao, Jian-gang, Liu, Dao-jun, Chen, Guang

Q ball solutions are considered within the theory of a complex scalar field with a gauged U(1) symmetry and a parabolic-type potential. In the thin-walled limit, we show explicitly that there is a...

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods (2001)

Sofia, Heidi J., Chen, Guang, Hetzler, Beth G., Reyes-Spindola, Jorge F., Miller, Nancy E.

A novel protein superfamily with over 600 members was discovered by iterative profile searches and analyzed with powerful bioinformatics and information visualization methods. Evidence exists that...

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

Sofia, Heidi J., Chen, Guang, Hetzler, Beth G., Reyes-Spindola, Jorge F., Miller, Nancy E.

A novel protein superfamily with over 600 members was discovered by iterative profile searches and analyzed with powerful bioinformatics and information visualization methods. Evidence exists that...

Defining the mammalian CArGome

Sun, Qiang, Chen, Guang, Streb, Jeffrey W., Long, Xiaochun, Yang, Yumei, Stoeckert, Christian J., ...

Serum response factor (SRF) binds a 1,216-fold degenerate cis element known as the CArG box. CArG boxes are found primarily in muscle and growth factor-associated genes though the full spectrum of...

Determination of theophylline concentration in serum by chemiluminescent immunoassay

Zhou, Mei-xia, Guan, Cha-ying, Chen, Guang, Xie, Xin-you, Wu, Sheng-hai

Objective: This study aimed to establish chemiluminescent immunoassay (CLIA) for quantitative determination of theophylline levels in human serum. Methods: To measure the concentration of...

Radical SAM, a novel protein superfamily linking unresolved steps in familiar biosynthetic pathways with radical mechanisms: functional characterization using new analysis and information visualization methods

Sofia, Heidi J., Chen, Guang, Hetzler, Beth G., Reyes-Spindola, Jorge F., Miller, Nancy E.

A novel protein superfamily with over 600 members was discovered by iterative profile searches and analyzed with powerful bioinformatics and information visualization methods. Evidence exists that...

Defining the mammalian CArGome

Sun, Qiang, Chen, Guang, Streb, Jeffrey W., Long, Xiaochun, Yang, Yumei, Stoeckert, Christian J., ...

Serum response factor (SRF) binds a 1,216-fold degenerate cis element known as the CArG box. CArG boxes are found primarily in muscle and growth factor-associated genes though the full spectrum of...

Determination of theophylline concentration in serum by chemiluminescent immunoassay

Zhou, Mei-xia, Guan, Cha-ying, Chen, Guang, Xie, Xin-you, Wu, Sheng-hai

Objective: This study aimed to establish chemiluminescent immunoassay (CLIA) for quantitative determination of theophylline levels in human serum. Methods: To measure the concentration of...

Clustering of genes into regulons using integrated modeling-COGRIM

Chen, Guang, Jensen, Shane T, Stoeckert, Christian J

COGRIM, an implementation that integrates gene expression, ChIP binding and transcription factor motif data, is described and applied to both unicellular and mammalian organisms.

Expansion of adult β-cell mass in response to increased metabolic demand is dependent on HNF-4α

Gupta, Rana K., Gao, Nan, Gorski, Regina K., White, Peter, Hardy, Olga T., Rafiq, Kiran, ...

The failure to expand functional pancreatic β-cell mass in response to increased metabolic demand is a hallmark of type 2 diabetes. Lineage tracing studies indicate that replication of existing...

Systems biology-defined NF-κB regulons, interacting signal pathways and networks are implicated in the malignant phenotype of head and neck cancer cell lines differing in p53 status

Yan, Bin, Chen, Guang, Saigal, Kunal, Yang, Xinping, Jensen, Shane T, Van Waes, Carter, ...

Detailed analysis of NFκB regulons in 1,265 genes differentially expressed in head and neck cancer cell lines differing in p53 status revealed a cross talk between NFkB and specific signaling...

NUMERICAL INVESTIGATIONS ON EFFECTS OF IMPACT VELOCITY AND SPRAY ANGLE OF PARTICLE ON ITS DEFORMATION BEHAVIOR IN COLD SPRAYING

XINPING ZHANG, XUEZHENG WANG, YUXUAN LI, GUANG CHEN

The cold spraying process is analyzed by numerical modeling of the impact between a single spherical particle and a substrate; the effects of impact velocity and spray angle of a particle on the...

BAG1 plays a critical role in regulating recovery from both manic-like and depression-like behavioral impairments

Maeng, Sungho, Hunsberger, Joshua G., Pearson, Brandon, Yuan, Peixiong, Wang, Yun, Wei, Yanling, ...

Recent microarray studies with stringent validating criteria identified Bcl-2-associated athanogene (BAG1) as a target for the actions of medications that are mainstays in the treatment of bipolar...

Reverse translational strategies for developing animal models of bipolar disorder

Malkesman, Oz, Austin, Daniel R., Chen, Guang, Manji, Husseini K.

Bipolar disorder (BD) affects a significant portion of the population of the world, yet there has been limited success in developing novel treatments for the disorder. One of the major reasons for...

Berberine reverses free-fatty-acid-induced insulin resistance in 3T3-L1 adipocytes through targeting IKKβ

Yi, Ping, Lu, Fu-Er, Xu, Li-Jun, Chen, Guang, Dong, Hui, Wang, Kai-Fu

AIM: To investigate the effects and molecular mechanisms of berberine on improving insulin resistance induced by free fatty acids (FFAs) in 3T3-L1 adipocytes.

Scaling and Memory Effect in Volatility Return Interval of the Chinese Stock Market

Tian Qiu, Liang Guo, Guang Chen

We investigate the probability distribution of the volatility return intervals $\tau$ for the Chinese stock market. We rescale both the probability distribution $P_{q}(\tau)$ and the volatility...

Characteristics of paraesophageal varices: A study with 64-row multidetector computed tomography portal venography

Zhao, Li-Qin, He, Wen, Chen, Guang

AIM: To identify the characteristics of morphology, location and collateral circulation involved in paraesophageal varices (para-EV) of portal hypertension patients with 64-row multidetector computed...

Computed tomography perfusion in evaluating the therapeutic effect of transarterial chemoembolization for hepatocellular carcinoma

Chen, Guang, Ma, Da-Qing, He, Wen, Zhang, Bao-Feng, Zhao, Li-Qin

AIM: To prospectively assess the changes in parameters of computed tomography (CT) perfusion pre- and post-transarterial chemoembolization (TACE) of hepatocellular carcinoma (HCC) in different...

Facilitating effects of berberine on rat pancreatic islets through modulating hepatic nuclear factor 4 alpha expression and glucokinase activity

Wang, Zhi-Quan, Lu, Fu-Er, Leng, San-Hua, Fang, Xin-Sheng, Chen, Guang, Wang, Zeng-Si, ...

AIM: To observe the effect of berberine on insulin secretion in rat pancreatic islets and to explore its possible molecular mechanism.