Dynamical Instabilities (2009)
Thermochemical systems appear in applications as widespread as in combustion engines, in industrial chemical plants and inside biological cells. Science in all these areas is going towards a more...
Computational disease modeling – fact or fiction? (2009)
Tegnér, Jesper N, Compte, Albert, Auffray, Charles, An, Gary, Cedersund, Gunnar, Clermont, Gilles, ...
Abstract Background Biomedical research is changing due to the rapid accumulation of experimental data at an unprecedented scale, revealing increasing degrees of complexity of biological processes....
Computational disease modeling - fact or fiction? (2009)
Tegner, Jesper N, Compte, Albert, Auffray, Charles, An, Gary, Cedersund, Gunnar, Clermont, Gilles, ...
Background: Biomedical research is changing due to the rapid accumulation of experimental data at an unprecedented scale, revealing increasing degrees of complexity of biological processes. Life...
Complexity reduction of biochemical rate expressions (2008)
Schmidt, Henning, Madsen, Mads F., Danø, Sune, Cedersund, Gunnar
Motivation: The current trend in dynamical modelling of biochemical systems is to construct more and more mechanistically detailed and thus complex models. The complexity is reflected in the number...
Jonas Biteus, Gunnar Cedersund, Erik Frisk, Mattias Krys, Lars Nielsen, Lars Nielsen
Language
Model-Based Hypothesis Testing of Key Mechanisms in Initial Phase of Insulin Signaling
Cedersund, Gunnar, Roll, Jacob, Ulfhielm, Erik, Danielsson, Anna, Tidefelt, Henrik, Strålfors, Peter
Type 2 diabetes is characterized by insulin resistance of target organs, which is due to impaired insulin signal transduction. The skeleton of signaling mediators that provide for normal insulin...