Guohua Wang

Genome-wide prediction of cis-acting RNA elements regulating tissue-specific pre-mRNA alternative splicing (2009)

Wang, Xin, Wang, Kejun, Radovich, Milan, Wang, Yue, Wang, Guohua, Feng, Weixing, ...

Abstract Background Human genes undergo various patterns of pre-mRNA splicing across different tissues. Such variation is primarily regulated by trans -acting factors that bind on exonic and intronic...

Reconstruct gene regulatory network using slice pattern model (2009)

Wang, Yadong, Wang, Guohua, Yang, Bo, Tao, Haijun, Yang, Jack Y, Deng, Youping, ...

Abstract Background Gene expression time series array data has become a useful resource for investigating gene functions and the interactions between genes. However, the gene expression arrays are...

miR2Disease: a manually curated database for microRNA deregulation in human disease (2009)

Jiang, Qinghua, Wang, Yadong, Hao, Yangyang, Juan, Liran, Teng, Mingxiang, Zhang, Xinjun, ...

‘miR2Disease’, a manually curated database, aims at providing a comprehensive resource of microRNA deregulation in various human diseases. The current version of miR2Disease documents 1939...

Estradiol-regulated microRNAs control estradiol response in breast cancer cells (2009)

Bhat-Nakshatri, Poornima, Wang, Guohua, Collins, Nikail R., Thomson, Michael J., Geistlinger, Tim R., Carroll, Jason S., ...

Estradiol (E2) regulates gene expression at the transcriptional level by functioning as a ligand for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). E2-inducible proteins c-Myc and...

Transcription factor and microRNA regulation in androgen-dependent and -independent prostate cancer cells (2008)

Wang, Guohua, Wang, Yadong, Feng, Weixing, Wang, Xin, Yang, Jack Y, Zhao, Yuming, ...

Abstract Background Prostate cancer is one of the leading causes of cancer death in men. Androgen ablation, the most commonly-used therapy for progressive prostate cancer, is ineffective once the...

Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome (2008)

Wang, Guohua, Wang, Xin, Wang, Yadong, Yang, Jack Y, Li, Lang, Nephew, Kenneth P, ...

Abstract This is a first report, using our MotifModeler informatics program, to simultaneously identify transcription factor (TF) and microRNA (miRNA) binding sites from gene expression microarray...

Using RNase sequence specificity to refine the identification of RNA-protein binding regions (2008)

Wang, Xin, Wang, Guohua, Shen, Changyu, Li, Lang, Wang, Xinguo, Mooney, Sean D, ...

Abstract Massively parallel pyrosequencing is a high-throughput technology that can sequence hundreds of thousands of DNA/RNA fragments in a single experiment. Combining it with...

MOLECULAR COMPOSITION OF NEEDLE COKE FEEDSTOCKS AND MESOPHASE DEVELOPMENT DURING CARBONIZATION (2008)

Wang, Guohua

This study investigates the molecular composition of fluid catalytic cracking (FCC) decant oil and its derivatives that are used as feedstocks for delayed coking to produce needle coke. Needle coke...

Identification of Differentially Expressed Genes in L02 Human Hepatocyte Induced by Hepatitis C Virus Core Protein (2008)

Xiaoyan Feng, Heqiu Zhang, Xiaoguo Song, Guohua Wang, Kun Chen, Bingshui Xiu, ...

Background and Aims: Hepatitis C virus (HCV) infection represents a major problem of public health with 170 million chronically infected individuals worldwide. It has been reported that HCV core...

Mapping verbal responses to numerical scales in the analytic hierarchy process

Liang, Liang, Wang, Guohua, Hua, Zhongsheng, Zhang, Bin

Using RNase sequence specificity to refine the identification of RNA-protein binding regions

Wang, Xin, Wang, Guohua, Shen, Changyu, Li, Lang, Wang, Xinguo, Mooney, Sean D, ...

Massively parallel pyrosequencing is a high-throughput technology that can sequence hundreds of thousands of DNA/RNA fragments in a single experiment. Combining it with immunoprecipitation-based...

Identification of transcription factor and microRNA binding sites in responsible to fetal alcohol syndrome

Wang, Guohua, Wang, Xin, Wang, Yadong, Yang, Jack Y, Li, Lang, Nephew, Kenneth P, ...

This is a first report, using our MotifModeler informatics program, to simultaneously identify transcription factor (TF) and microRNA (miRNA) binding sites from gene expression microarray data. Based...

Transcription factor and microRNA regulation in androgen-dependent and -independent prostate cancer cells

Wang, Guohua, Wang, Yadong, Feng, Weixing, Wang, Xin, Yang, Jack Y, Zhao, Yuming, ...

miR2Disease: a manually curated database for microRNA deregulation in human disease

Jiang, Qinghua, Wang, Yadong, Hao, Yangyang, Juan, Liran, Teng, Mingxiang, Zhang, Xinjun, ...

‘miR2Disease’, a manually curated database, aims at providing a comprehensive resource of microRNA deregulation in various human diseases. The current version of miR2Disease documents 1939...

AKT Alters Genome-Wide Estrogen Receptor α Binding and Impacts Estrogen Signaling in Breast Cancer▿ †

Bhat-Nakshatri, Poornima, Wang, Guohua, Appaiah, Hitesh, Luktuke, Nikhil, Carroll, Jason S., Geistlinger, Tim R., ...

Estrogen regulates several biological processes through estrogen receptor α (ERα) and ERβ. ERα-estrogen signaling is additionally controlled by extracellular signal activated kinases such as AKT....

Reconstruct gene regulatory network using slice pattern model

Wang, Yadong, Wang, Guohua, Yang, Bo, Tao, Haijun, Yang, Jack Y, Deng, Youping, ...

Genome-wide prediction of cis-acting RNA elements regulating tissue-specific pre-mRNA alternative splicing

Wang, Xin, Wang, Kejun, Radovich, Milan, Wang, Yue, Wang, Guohua, Feng, Weixing, ...

Estradiol-regulated microRNAs control estradiol response in breast cancer cells

Bhat-Nakshatri, Poornima, Wang, Guohua, Collins, Nikail R., Thomson, Michael J., Geistlinger, Tim R., Carroll, Jason S., ...

Estradiol (E2) regulates gene expression at the transcriptional level by functioning as a ligand for estrogen receptor alpha (ERα) and estrogen receptor beta (ERβ). E2-inducible proteins c-Myc and...