Hélène Touzet

Alignments of RNA structures (2009)

Guillaume Blin, Alain Denise, Serge Dulucq, Claire Herrbach, Hélène Touzet

Abstract — We describe a theoretical unifying framework to express comparison of RNA structures, which we call alignment hierarchy. This framework relies on the definition of common supersequences...

Does Hybridization Increase Evolutionary Rate? Data from the 28S-rDNA D8 Domain in Echinoderms (2009)

Hélène Touzet, A. Chenuil, H. Touzet

Abstract The divergent domain D8 of the large ribosomal RNA is very variable and extended in vertebrates compared to other eukaryotes. We provide data from 31 species of echinoderms and present the...

par des (2008)

Aude Liefooghe, Hélène Touzet, Jean-stéphane Varré, Lifl Umr

à grande échelle de motifs nucléiques décrits

Recherche d’éléments régulateurs communs, application aux gènes cibles des facteurs de transcription Rel/NF-κB (2008)

Matthieu Defrance, Hélène Touzet, Karo Gosselin, Corinne Abbadie

Résumé. Le but de ce travail est l’analyse des régions régulatrices pour des ensembles de gènes partageant des mécanismes de régulation transcriptionnelle. Nous présentons une stratégie...

Rapport de Recherche N ° 1451 (2008)

Paris Sud, Claire Herrbach, Alain Denise, Serge Dulucq, Hélène Touzet

Alignment of RNA secondary structures using a full set of operations

Decomposition Algorithms for the Tree Edit (2008)

Distance Problem Serge, Serge Dulucq, Hélène Touzet

We study the behavior of dynamic programming methods for the tree edit distance problem, such as [5,13]. We show that those two algorithms may be described as decomposition strategies. We introduce...

A Fast Algorithm for Analysing Regulatory Regions of Related Genes Matthieu Defrance, Helene Touzet, Stephane Janot (2008)

Umr Cnrs Lifl, Matthieu Defrance, Hélène Touzet, Stéphane Janot

Introduction The first step toward the modelling of a transcriptional genetic network is to understand which are the transcription factors that are involved in the process. It is possible to...

MAGNOLIA: multiple alignment of protein-coding and structural RNA sequences (2008)

Fontaine, Arnaud, De Monte, Antoine, Touzet, Hélène

MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking...

Efficient and accurate P-value computation for Position Weight Matrices (2007)

Touzet, Hélène, Varré, Jean-Stéphane

Abstract Background Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The...

Efficient and accurate P-value computation for Position Weight Matrices (2007)

Touzet, Hélène, Varré, Jean-Stéphane

Background Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The usage of...

Efficient and accurate P-value computation for Position Weight Matrices (2007)

Touzet, Hélène, Varré, Jean-Stéphane

Background Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The usage of...

Algorithms for Molecular Biology Research Efficient and accurate P-value computation for Position Weight Matrices (2007)

Hélène Touzet, Jean-stéphane Varré

Background: Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The usage of...

Predicting transcription factor binding sites using local over-representation and comparative genomics (2006)

Defrance, Matthieu, Touzet, Hélène

Abstract Background Identifying cis -regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented transcription...

How to compare arc-annotated sequences : the alignment hierarchy (2006)

Guillaume Blin, Hélène Touzet

Abstract. We describe a new unifying framework to express comparison of arc-annotated sequences, which we call alignment of arc-annotated sequences. We first prove that this framework encompasses...

Large Scale Matching for Position Weight Matrices (2006)

Aude Liefooghe, Hélène Touzet, Jean-stéphane Varré

Abstract. This paper addresses the problem of multiple pattern matching for motifs encoded by Position Weight Matrices. We first present an algorithm that uses a multi-index table to preprocess the...

How to detect non-coding RNAs ? (2005)

Arnaud Fontaine, Hélène Touzet

Structured non-coding RNAs have a very important functional role in the cell. They are involved in a variety of processes such as transcriptional and post-transcriptional regulation, chromosome...

A Linear Tree Edit Distance Algorithm for Similar Ordered Trees (2005)

Hélène Touzet

We describe a linear algorithm for comparing two similar ordered rooted trees with node labels. The method for comparing trees is the usual tree edit distance. We show that an optimal mapping which...

CARNAC: folding families of related RNAs (2004)

Touzet, Hélène, Perriquet, Olivier

We present a tool for the prediction of conserved secondary structure elements of a family of homologous non-coding RNAs. Our method does not require any prior multiple sequence alignment. Thus, it...

Tree Edit Distance With Gaps (2003)

Helene Touzet Lifl, Hélène Touzet

this paper is to study the definition of edit distances with convex gap weights for trees. In the special case of strings, this problem has yield to the definition of classical solutions: Galil and...

Analysis of tree edit distance algorithms Serge Dulucq (2003)

And Helene Touzet, Serge Dulucq, Hélène Touzet

In this article, we study the behaviour of dynamic programming methods for the tree edit distance problem, such as [4] and [2]. We show that those two algorithms may be described in a more general...

Encoding the Hydra Battle as a rewrite system (1998)

Hélène Touzet

. In rewriting theory, termination of a rewrite system by Kruskal's theorem implies a theoretical upper bound on the complexity of the system. This bound is, however, far from having been...

CARNAC: folding families of related RNAs

Touzet, Hélène, Perriquet, Olivier

We present a tool for the prediction of conserved secondary structure elements of a family of homologous non-coding RNAs. Our method does not require any prior multiple sequence alignment. Thus, it...

CARNAC: folding families of related RNAs

Touzet, Hélène, Perriquet, Olivier

We present a tool for the prediction of conserved secondary structure elements of a family of homologous non-coding RNAs. Our method does not require any prior multiple sequence alignment. Thus, it...

MAGNOLIA: multiple alignment of protein–coding and structural RNA sequences

Fontaine, Arnaud, De Monte, Antoine, Touzet, Hélène

MAGNOLIA is a new software for multiple alignment of nucleic acid sequences, which are recognized to be hard to align. The idea is that the multiple alignment process should be improved by taking...